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Tag Content
UUCD2 ID IUUC-Dre-028556
UUCD1 version UUC-DaR-01445
Ensembl Protein ID ENSDARP00000116060.1
UniProt Accession B7ZDA8; B7ZDA8_DANRE
Genbank Protein ID ENSDARP00000116060
Protein Name Ubiquitin-specific peptidase 19
Genbank Nucleotide ID AL953864
Gene Name usp19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000004132.10 ENSDART00000147778.1 ENSDARP00000116060.1
ENSDARG00000004132.10 ENSDART00000112840.3 ENSDARP00000100933.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 3.50e-107 359.4 638 1355
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl NlgNtC+mNSv+Q+Lsn++elr+++++  +++++n +np ++ g+l+  ++ l+++lwk++++a++p++l+++++++a++f+g
   Q: 638  TGLVNLGNTCFMNSVIQSLSNTRELRDYFHDrGFESEINCNNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTG 724
           7******************************889***************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d   ++de     a++++k++n+s+i+dlFqgq+ks+++       s +++p
   Q: 725  YAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSD--GRQDEvvaeeAWQRHKMRNDSFIVDLFQGQYKSKLV-------SITFDP 802
           ********************************9998..5555556777**********************9885.......79**** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           fl+l++p+p+k++  +                                                                       
   Q: 803  FLYLPVPLPQKQKVLTVfyfakephkkpvkflvsvskessstaevlesisrsvrikpenlrltevvkgrfhrifspsqsldtvsssd 889
           ************87555********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 890  llfcfemlskdlikervvllkvqqrpqipsipitkcagclkppasddeklkrctrcyrvgycnqtcqknhwpshktmcrsnvenigq 976
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 977  pflisvpesrlsytrltqllegysrysvnvfqppfqsgrtspesslsrvdltsmassvpecqekdlpsagdpenpaeqdesvtasqt 1063
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1064 esaadggdtlsthttdsgccelassshdslleketscekavkpeavvtgyqqpsesasggasqfyitildssqkedkkleekgdavl 1150
           *************************************************************************************** PP
   S: 186  ...............................................slqdcLesftkeeelegenkyycekckkkqeaekklklkk 225
                                                          +l++cL+ ftk+e l  e+++yc+kc++++ea+k+l l++
   Q: 1151 elpdectlelvwknnerqkeyvlvrskdlefdedpgsatetsraghfTLEQCLNLFTKPEVLAPEEAWYCPKCQQHREASKQLLLWR 1237
           *************************************************************************************** PP
   S: 226  lPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk...... 305
           lP+vLi++LkRfsf++  +++ kin+ v+fp + Ldls+fc+  + + +++ +Y+L+av++H+G++ +GHY+ay++  ++k      
   Q: 1238 LPNVLIIQLKRFSFRSFIWRD-KINDMVDFPVRnLDLSKFCIGHKGDIQQPPIYDLYAVINHYGGMIGGHYTAYARLPSDKnsqlsd 1323
           *****************8886.**********9*******************************************95444456777 PP
   S: 306  ..WllfdDskVtevkeeevleetgstaYvlfYkrr 338
             W lfdDs+Vt+v+e++v++   + aYvlfY+rr
   Q: 1324 vgWRLFDDSTVTTVEESQVVT---RYAYVLFYRRR 1355
           78*******************...********996 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MASSSTGSSE SGRRRGQRGP DDTVSTSKKK QKDRANQESK EAKRVATSTE TKKDLFLDWK 60
QNAYEVIVRL NCGGAGELRV EDIEYDFSNS ACHIRLPDGR EWSCHLHEEI EASCSKLNYK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028556|DUB,USP|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGTTTGGGCA GGCAGGCAGG TTGGCGTGAT CTCCGTCTCT ACCCGGTTTG TTTTGTTCTC 60
TAACAAAGTG CGAGTGACGG AGCGGCGCTC GGCTCATCGG GTAGAGCACG GACAGCGTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028556|DUB,USP|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR007052--CS_dom
IPR008978--HSP20-like_chaperone
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND
PROSITE

PS51203--CS
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2
Pfam

PF04969--CS
PF00443--UCH
PF01753--zf-MYND
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0046872--F:metal ion binding
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001999 Ailuropoda melanoleuca 68.93 0.00e+00 1360.00
IUUC-Apl-003368 Anas platyrhynchos 70.69 0.00e+00 1379.00
IUUC-Aca-004267 Anolis carolinensis 71.27 0.00e+00 1387.00
IUUC-Ame-010970 Astyanax mexicanus 72.22 0.00e+00 1906.00
IUUC-Bta-012905 Bos taurus 68.92 0.00e+00 1342.00
IUUC-Cel-018257 Caenorhabditis elegans 42.48 5.00e-91 329.00
IUUC-Cja-018789 Callithrix jacchus 68.42 0.00e+00 1357.00
IUUC-Cfa-021004 Canis familiaris 68.82 0.00e+00 1340.00
IUUC-Cpo-021529 Cavia porcellus 69.62 0.00e+00 1322.00
IUUC-Csa-024035 Chlorocebus sabaeus 69.49 0.00e+00 1373.00
IUUC-Cho-025036 Choloepus hoffmanni 70.56 0.00e+00 634.00
IUUC-Cin-025451 Ciona intestinalis 38.66 6.00e-81 296.00
IUUC-Csv-025931 Ciona savignyi 42.15 5.00e-54 206.00
IUUC-Dno-029240 Dasypus novemcinctus 66.44 0.00e+00 1280.00
IUUC-Dor-030495 Dipodomys ordii 68.42 0.00e+00 828.00
IUUC-Ete-032741 Echinops telfairi 68.62 0.00e+00 1326.00
IUUC-Eca-033661 Equus caballus 68.82 0.00e+00 1361.00
IUUC-Eeu-034648 Erinaceus europaeus 74.63 5.00e-171 595.00
IUUC-Fca-035646 Felis catus 68.69 0.00e+00 1345.00
IUUC-Fal-037094 Ficedula albicollis 67.81 0.00e+00 1462.00
IUUC-Gmo-038869 Gadus morhua 72.24 0.00e+00 1434.00
IUUC-Gga-041170 Gallus gallus 68.08 0.00e+00 1427.00
IUUC-Gac-041901 Gasterosteus aculeatus 72.91 0.00e+00 1519.00
IUUC-Ggo-044708 Gorilla gorilla 70.04 0.00e+00 1355.00
IUUC-Hsa-046791 Homo sapiens 70.04 0.00e+00 1351.00
IUUC-Itr-048892 Ictidomys tridecemlineatus 69.60 0.00e+00 1288.00
IUUC-Lch-050456 Latimeria chalumnae 62.87 0.00e+00 1118.00
IUUC-Loc-052861 Lepisosteus oculatus 58.84 0.00e+00 1452.00
IUUC-Laf-053788 Loxodonta africana 69.78 0.00e+00 1342.00
IUUC-Mcc-055693 Macaca mulatta 69.32 0.00e+00 1366.00
IUUC-Meu-055921 Macropus eugenii 70.70 0.00e+00 1164.00
IUUC-Mga-059879 Meleagris gallopavo 67.57 0.00e+00 1417.00
IUUC-Mmr-060802 Microcebus murinus 67.66 0.00e+00 1365.00
IUUC-Mdo-061856 Monodelphis domestica 66.82 0.00e+00 1341.00
IUUC-Mmu-063874 Mus musculus 64.22 0.00e+00 1355.00
IUUC-Mpu-066166 Mustela putorius furo 67.94 0.00e+00 1336.00
IUUC-Nle-070161 Nomascus leucogenys 69.26 0.00e+00 1356.00
IUUC-Opr-071015 Ochotona princeps 68.98 0.00e+00 1320.00
IUUC-Ont-072308 Oreochromis niloticus 64.60 0.00e+00 1736.00
IUUC-Oan-072723 Ornithorhynchus anatinus 64.99 0.00e+00 1335.00
IUUC-Ocu-073938 Oryctolagus cuniculus 70.23 0.00e+00 1338.00
IUUC-Ola-086375 Oryzias latipes 76.97 0.00e+00 1537.00
IUUC-Oga-088297 Otolemur garnettii 67.40 0.00e+00 1350.00
IUUC-Oar-089675 Ovis aries 69.22 0.00e+00 1191.00
IUUC-Ptr-091621 Pan troglodytes 69.83 0.00e+00 1349.00
IUUC-Pan-092118 Papio anubis 69.49 0.00e+00 1373.00
IUUC-Pfo-097246 Poecilia formosa 68.31 0.00e+00 1533.00
IUUC-Pab-098551 Pongo abelii 69.11 0.00e+00 1333.00
IUUC-Pca-100158 Procavia capensis 63.09 0.00e+00 1294.00
IUUC-Pva-103160 Pteropus vampyrus 68.74 0.00e+00 1325.00
IUUC-Rno-105355 Rattus norvegicus 65.02 0.00e+00 1343.00
IUUC-Sha-107057 Sarcophilus harrisii 71.30 0.00e+00 1346.00
IUUC-Sar-113011 Sorex araneus 64.34 0.00e+00 972.00
IUUC-Ssc-115761 Sus scrofa 67.72 0.00e+00 1348.00
IUUC-Tgu-116956 Taeniopygia guttata 56.74 0.00e+00 775.00
IUUC-Tru-118739 Takifugu rubripes 74.06 0.00e+00 1509.00
IUUC-Tsy-118827 Tarsius syrichta 76.96 0.00e+00 681.00
IUUC-Tni-119921 Tetraodon nigroviridis 71.79 0.00e+00 1484.00
IUUC-Tbe-128017 Tupaia belangeri 66.93 0.00e+00 1306.00
IUUC-Ttr-128869 Tursiops truncatus 65.71 0.00e+00 1346.00
IUUC-Vpa-130427 Vicugna pacos 62.08 1.00e-174 607.00
IUUC-Xtr-132734 Xenopus tropicalis 73.28 0.00e+00 1399.00
Created Date 25-Jun-2017

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