iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033469

Ensembl Protein ID

ENSECAP00000011417.1

UniProt Accession

F7BIS4; F7BIS4_HORSE

Protein Name

Uncharacterized protein

Gene Name

ITSN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000012054.1	ENSECAT00000014296.1	ENSECAP00000011417.1
ENSECAG00000012054.1	ENSECAT00000014380.1	ENSECAP00000011494.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.20e-67	221.6	1156	1207

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+ +ydy+aqnddeL ++kG ++ v+  +++d +W+kg  e +g+ GlfP+n+v+
   Q: 1156 QVIGMYDYTAQNDDELAFNKGQIINVL--NKEDPDWWKG--EVNGQVGLFPSNYVK 1207
           46678**********************..8889******..9*************8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAQFPTPFGG NLDIWTITAE RAKHDQQAPY LEPVCGFLKC DQARNFFFQS GLPQPVLAQI 60
WALADMNNDG RMDQVEFSIA MKLIKLKLQG YQLPSALPPV MKQQPVAISS APAFGIGGIA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCAGT TTCCAACACC TTTTGGTGGT AAGTTTGTAA AGATTTTCCT TTTTTAATGT 60
ACTTTGAAAC CATATTTTAA AAAGCTCAGT ATTATGGCAA ATTTCAAATA CACACGTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	41.67	3.00e-14	74.70
IUUC-Aml-001218	Ailuropoda melanoleuca	95.95	0.00e+00	2424.00
IUUC-Apl-003335	Anas platyrhynchos	91.67	0.00e+00	2263.00
IUUC-Aca-005130	Anolis carolinensis	89.59	0.00e+00	2239.00
IUUC-Ago-007935	Ashbya gossypii	34.59	2.00e-14	73.90
IUUC-Ani-009403	Aspergillus nidulans	39.66	4.00e-15	73.20
IUUC-Ang-009722	Aspergillus niger	31.45	1.00e-16	82.00
IUUC-Aor-010021	Aspergillus oryzae	30.06	5.00e-18	86.70
IUUC-Ate-010587	Aspergillus terreus	33.55	5.00e-17	83.20
IUUC-Ame-011878	Astyanax mexicanus	76.21	0.00e+00	1941.00
IUUC-Bta-012863	Bos taurus	95.87	0.00e+00	2372.00
IUUC-Bdi-014016	Brachypodium distachyon	40.00	5.00e-14	73.60
IUUC-Cja-019012	Callithrix jacchus	96.66	0.00e+00	2399.00
IUUC-Cfa-020272	Canis familiaris	96.19	0.00e+00	2438.00
IUUC-Cpo-021352	Cavia porcellus	87.42	0.00e+00	2825.00
IUUC-Cho-024969	Choloepus hoffmanni	84.64	0.00e+00	1910.00
IUUC-Cin-025435	Ciona intestinalis	45.62	0.00e+00	977.00
IUUC-Csv-026290	Ciona savignyi	57.89	0.00e+00	781.00
IUUC-Dre-028623	Danio rerio	76.67	0.00e+00	1951.00
IUUC-Dno-030044	Dasypus novemcinctus	95.49	0.00e+00	2395.00
IUUC-Dor-030272	Dipodomys ordii	88.60	0.00e+00	2089.00
IUUC-Ete-032927	Echinops telfairi	98.20	0.00e+00	1034.00
IUUC-Eeu-034977	Erinaceus europaeus	91.63	0.00e+00	1127.00
IUUC-Fca-036419	Felis catus	95.79	0.00e+00	2377.00
IUUC-Fal-037236	Ficedula albicollis	89.78	0.00e+00	2256.00
IUUC-Gmo-039632	Gadus morhua	70.42	0.00e+00	1684.00
IUUC-Gga-040835	Gallus gallus	89.75	0.00e+00	2239.00
IUUC-Gac-041948	Gasterosteus aculeatus	72.13	0.00e+00	1806.00
IUUC-Hsa-045699	Homo sapiens	97.06	0.00e+00	2460.00
IUUC-Hvu-047530	Hordeum vulgare	33.14	1.00e-14	75.10
IUUC-Itr-048773	Ictidomys tridecemlineatus	92.72	0.00e+00	2343.00
IUUC-Lch-050502	Latimeria chalumnae	78.57	0.00e+00	1636.00
IUUC-Lpe-051250	Leersia perrieri	41.67	2.00e-14	74.70
IUUC-Loc-052613	Lepisosteus oculatus	81.04	0.00e+00	1972.00
IUUC-Laf-053608	Loxodonta africana	94.11	0.00e+00	2396.00
IUUC-Mcc-055720	Macaca mulatta	96.58	0.00e+00	2413.00
IUUC-Meu-056445	Macropus eugenii	84.99	0.00e+00	1707.00
IUUC-Mla-059128	Melampsora laricipopulina	29.35	5.00e-40	160.00
IUUC-Mvi-060268	Microbotryum violaceum	29.67	2.00e-43	171.00
IUUC-Mmr-061258	Microcebus murinus	96.66	0.00e+00	2398.00
IUUC-Mdo-062019	Monodelphis domestica	92.06	0.00e+00	2243.00
IUUC-Mmu-063885	Mus musculus	94.12	0.00e+00	2410.00
IUUC-Mlu-067025	Myotis lucifugus	66.54	0.00e+00	1473.00
IUUC-Nle-069448	Nomascus leucogenys	86.28	0.00e+00	1228.00
IUUC-Opr-070441	Ochotona princeps	90.11	0.00e+00	2088.00
IUUC-Ont-071752	Oreochromis niloticus	70.71	0.00e+00	1722.00
IUUC-Oan-073390	Ornithorhynchus anatinus	87.79	0.00e+00	2166.00
IUUC-Ocu-073753	Oryctolagus cuniculus	92.73	0.00e+00	2980.00
IUUC-Obr-076390	Oryza brachyantha	36.14	5.00e-09	55.10
IUUC-Ogu-078849	Oryza glumaepatula	41.67	3.00e-14	74.30
IUUC-Olo-080259	Oryza longistaminata	41.67	2.00e-14	75.10
IUUC-Ome-081199	Oryza meridionalis	41.67	2.00e-14	74.70
IUUC-Oni-082167	Oryza nivara	41.67	5.00e-14	73.60
IUUC-Oru-084541	Oryza rufipogon	41.67	5.00e-14	73.60
IUUC-Ola-087489	Oryzias latipes	44.63	0.00e+00	1322.00
IUUC-Olu-087698	Ostreococcus lucimarinus	27.52	1.00e-15	78.20
IUUC-Oga-088602	Otolemur garnettii	96.35	0.00e+00	2388.00
IUUC-Oar-090195	Ovis aries	95.88	0.00e+00	2375.00
IUUC-Ptr-091363	Pan troglodytes	97.14	0.00e+00	2461.00
IUUC-Pan-092385	Papio anubis	96.36	0.00e+00	2414.00
IUUC-Pfo-097486	Poecilia formosa	74.41	0.00e+00	1840.00
IUUC-Pab-098281	Pongo abelii	85.56	0.00e+00	2071.00
IUUC-Pop-098963	Populus trichocarpa	40.24	3.00e-11	64.70
IUUC-Pca-100270	Procavia capensis	79.17	0.00e+00	1337.00
IUUC-Pva-102335	Pteropus vampyrus	93.65	0.00e+00	2360.00
IUUC-Ptt-103973	Puccinia triticina	24.54	3.00e-26	115.00
IUUC-Rno-106122	Rattus norvegicus	92.72	0.00e+00	2360.00
IUUC-Sha-106851	Sarcophilus harrisii	92.31	0.00e+00	2260.00
IUUC-Sja-107863	Schizosaccharomyces japonicus	31.85	2.00e-15	77.80
IUUC-Spo-108101	Schizosaccharomyces pombe	43.56	7.00e-16	79.30
IUUC-Sit-110414	Setaria italica	40.48	3.00e-14	74.30
IUUC-Sbi-114170	Sorghum bicolor	38.89	3.00e-14	74.70
IUUC-Tgu-117028	Taeniopygia guttata	90.73	0.00e+00	2291.00
IUUC-Tru-117789	Takifugu rubripes	76.37	0.00e+00	1868.00
IUUC-Tsy-119039	Tarsius syrichta	93.99	0.00e+00	1400.00
IUUC-Tni-119952	Tetraodon nigroviridis	74.04	0.00e+00	1731.00
IUUC-Tae-123242	Triticum aestivum	41.67	4.00e-14	73.90
IUUC-Tur-126623	Triticum urartu	40.00	3.00e-14	73.90
IUUC-Tbe-127754	Tupaia belangeri	84.34	0.00e+00	1708.00
IUUC-Ttr-129178	Tursiops truncatus	96.66	0.00e+00	2399.00
IUUC-Vpa-130687	Vicugna pacos	91.50	0.00e+00	1198.00
IUUC-Xtr-132905	Xenopus tropicalis	86.14	0.00e+00	2166.00
IUUC-Xma-134144	Xiphophorus maculatus	75.68	0.00e+00	1836.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence