iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066431

Ensembl Protein ID

ENSMPUP00000013895.1

UniProt Accession

M3YRD6; M3YRD6_MUSPF

Genbank Protein ID

ENSMPUP00000013895

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01019143

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000014000.1	ENSMPUT00000014115.1	ENSMPUP00000013895.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-59	198.1	1118	1170

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy a+n+deL++ kG  + v+  ++ d +W++g  e +g  GlfP+n+v+ 
   Q: 1118 QVIAMYDYVANNEDELNFSKGQLINVL--NKDDPDWWQG--EINGVTGLFPSNYVKM 1170
           6899***********************..8889******..9*************85 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MMAQFPTAMN GGPNMWAITS EERTKHDKQF DNLKPSGGYI TGDQARTFFL QSGLPAPVLA 60
EIWALSDLNK DGKMDQQEFS IAMKLIKLKL QGQQLPVVLP PIMKQPPMFS PLISARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATGTTCAG CTTCTGCAGA CCGGGTGGTG GGATTTGGGG AGAGATGAAC ATCTCATTGC 60
TCGGGAGAGT TTATGGGGTG GATGCTCTCC CAACCGGAGG CGGGCCCCTA CCTTGTTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	97.22	0.00e+00	2244.00
IUUC-Apl-004205	Anas platyrhynchos	79.34	0.00e+00	2412.00
IUUC-Aca-004287	Anolis carolinensis	79.84	0.00e+00	1665.00
IUUC-Ago-007935	Ashbya gossypii	32.03	4.00e-12	66.60
IUUC-Ame-011759	Astyanax mexicanus	64.57	0.00e+00	1241.00
IUUC-Bta-013248	Bos taurus	93.23	0.00e+00	2116.00
IUUC-Cel-018490	Caenorhabditis elegans	25.30	3.00e-51	197.00
IUUC-Cja-019012	Callithrix jacchus	57.32	0.00e+00	1408.00
IUUC-Cfa-020628	Canis familiaris	95.92	0.00e+00	2241.00
IUUC-Cpo-022427	Cavia porcellus	80.39	0.00e+00	2585.00
IUUC-Csa-023122	Chlorocebus sabaeus	94.31	0.00e+00	2164.00
IUUC-Cho-024969	Choloepus hoffmanni	53.29	0.00e+00	1134.00
IUUC-Cin-025435	Ciona intestinalis	44.46	0.00e+00	908.00
IUUC-Csv-026290	Ciona savignyi	53.90	0.00e+00	717.00
IUUC-Cne-026918	Cryptococcus neoformans	35.64	5.00e-38	154.00
IUUC-Cme-027247	Cyanidioschyzon merolae	28.32	4.00e-10	59.70
IUUC-Dre-027849	Danio rerio	65.06	0.00e+00	1212.00
IUUC-Dno-029419	Dasypus novemcinctus	94.80	0.00e+00	2203.00
IUUC-Dor-030504	Dipodomys ordii	78.12	0.00e+00	1742.00
IUUC-Dme-032099	Drosophila melanogaster	33.19	8.00e-56	212.00
IUUC-Ete-032927	Echinops telfairi	76.00	0.00e+00	822.00
IUUC-Eca-034196	Equus caballus	92.16	0.00e+00	2083.00
IUUC-Eeu-034972	Erinaceus europaeus	68.66	0.00e+00	638.00
IUUC-Fca-035757	Felis catus	95.26	0.00e+00	2231.00
IUUC-Fal-037531	Ficedula albicollis	87.21	0.00e+00	1714.00
IUUC-Gmo-039632	Gadus morhua	53.03	0.00e+00	1228.00
IUUC-Gga-041012	Gallus gallus	78.68	0.00e+00	1877.00
IUUC-Gac-041320	Gasterosteus aculeatus	53.97	0.00e+00	1278.00
IUUC-Ggo-045405	Gorilla gorilla	90.55	0.00e+00	2660.00
IUUC-Hsa-046833	Homo sapiens	93.39	0.00e+00	2141.00
IUUC-Itr-048773	Ictidomys tridecemlineatus	55.36	0.00e+00	1330.00
IUUC-Kpa-049215	Komagataella pastoris	36.17	1.00e-14	75.10
IUUC-Lch-050094	Latimeria chalumnae	72.62	0.00e+00	1691.00
IUUC-Loc-052646	Lepisosteus oculatus	71.12	0.00e+00	1424.00
IUUC-Laf-053798	Loxodonta africana	88.03	0.00e+00	1428.00
IUUC-Mcc-054709	Macaca mulatta	93.47	0.00e+00	2169.00
IUUC-Meu-056396	Macropus eugenii	80.44	0.00e+00	1532.00
IUUC-Mla-059128	Melampsora laricipopulina	34.44	6.00e-40	160.00
IUUC-Mga-059997	Meleagris gallopavo	82.73	0.00e+00	2002.00
IUUC-Mvi-060268	Microbotryum violaceum	30.85	4.00e-47	184.00
IUUC-Mmr-060891	Microcebus murinus	95.21	0.00e+00	2185.00
IUUC-Mdo-062019	Monodelphis domestica	57.71	0.00e+00	1385.00
IUUC-Mmu-064226	Mus musculus	87.52	0.00e+00	2146.00
IUUC-Mlu-068190	Myotis lucifugus	93.14	0.00e+00	2178.00
IUUC-Nle-070116	Nomascus leucogenys	90.78	0.00e+00	1694.00
IUUC-Opr-070815	Ochotona princeps	78.70	0.00e+00	1746.00
IUUC-Ont-072464	Oreochromis niloticus	64.56	0.00e+00	1223.00
IUUC-Oan-073390	Ornithorhynchus anatinus	55.73	0.00e+00	1322.00
IUUC-Ocu-073856	Oryctolagus cuniculus	78.94	0.00e+00	1888.00
IUUC-Ola-086482	Oryzias latipes	61.23	0.00e+00	1227.00
IUUC-Oga-088449	Otolemur garnettii	91.58	0.00e+00	2098.00
IUUC-Oar-090275	Ovis aries	93.64	0.00e+00	2157.00
IUUC-Ptr-091667	Pan troglodytes	92.98	0.00e+00	2127.00
IUUC-Pan-091723	Papio anubis	91.54	0.00e+00	1850.00
IUUC-Psi-093136	Pelodiscus sinensis	81.96	0.00e+00	1932.00
IUUC-Pfo-097486	Poecilia formosa	67.84	0.00e+00	1201.00
IUUC-Pab-098755	Pongo abelii	90.62	0.00e+00	2061.00
IUUC-Pca-101134	Procavia capensis	85.93	0.00e+00	1486.00
IUUC-Pva-102433	Pteropus vampyrus	86.68	0.00e+00	1949.00
IUUC-Pgr-103473	Puccinia graminis	30.27	1.00e-38	156.00
IUUC-Ptt-103973	Puccinia triticina	25.64	3.00e-27	119.00
IUUC-Rno-105691	Rattus norvegicus	92.07	0.00e+00	2201.00
IUUC-Sha-106851	Sarcophilus harrisii	64.97	0.00e+00	1311.00
IUUC-Sar-112978	Sorex araneus	90.08	0.00e+00	1412.00
IUUC-Sre-115028	Sporisorium reilianum	33.60	1.00e-33	139.00
IUUC-Ssc-115562	Sus scrofa	85.22	0.00e+00	1964.00
IUUC-Tgu-116758	Taeniopygia guttata	82.89	0.00e+00	2007.00
IUUC-Tru-117789	Takifugu rubripes	62.30	0.00e+00	1248.00
IUUC-Tsy-119039	Tarsius syrichta	70.07	0.00e+00	1067.00
IUUC-Tni-119958	Tetraodon nigroviridis	56.07	0.00e+00	1689.00
IUUC-Tbe-127477	Tupaia belangeri	90.48	0.00e+00	744.00
IUUC-Ttr-129196	Tursiops truncatus	90.48	0.00e+00	2071.00
IUUC-Uma-129456	Ustilago maydis	33.60	6.00e-32	134.00
IUUC-Vpa-130035	Vicugna pacos	80.69	0.00e+00	629.00
IUUC-Xtr-132905	Xenopus tropicalis	59.54	0.00e+00	1437.00
IUUC-Xma-133300	Xiphophorus maculatus	58.55	0.00e+00	1320.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence