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Tag Content
UUCD2 ID IUUC-Xtr-132719
UUCD1 version UUC-XeT-00158
Ensembl Protein ID ENSXETP00000050867.3
UniProt Accession F6RXA4; F6RXA4_XENTR
Genbank Protein ID ENSXETP00000050867
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAMC01063326
Gene Name herc4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000023570.3 ENSXETT00000050867.3 ENSXETP00000050867.3
ENSXETG00000023570.3 ENSXETT00000065255.1 ENSXETP00000061733.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.80e-101 340.0 720 1043
Active Site
Position(s) Description Evidence
1012 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           d kk ++v f gEe++d+gGv +ef+ l+++el +p++g+f+y e+++  ++ +++      e  +lF+++G+++g+a+++  +++l
   Q: 720  DYKKPMRVIFFGEEAIDAGGVRKEFFLLIMRELLDPKYGMFRYYEESRLIWFSDKTF-----EDSDLFHLIGVVCGLAIYNFTIIEL 801
           789999**********************************************98877.....689********************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklv 177
           +++ ++yk+ll+kk sledl+e++p + +s+++++++ e+diee+ ++l+f+++ e++g+t+++eL+p+G++ipV+ +N++++v+++
   Q: 802  HFPLALYKKLLKKKPSLEDLKELMPIIGRSMQQLLDYTEDDIEET-FCLNFTITVENFGTTEVRELIPNGAEIPVNRKNRQDFVDAY 887
           **************************************9999998.***************************************** PP
   S: 178  veyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
           v+y++++++++ + af++Gf++v+  ++l+lF+++el+ ++ G++ +d+++l+k t+ykg+y +d+p+i++Fwe+++++  e++k+f
   Q: 888  VDYIFNQSVASLFSAFSAGFHKVCGSKVLELFQPNELQAMVIGNTAYDWKELEKSTEYKGEYWADHPTIKMFWEIFHALPLEKKKQF 974
           *************************************************************************************** PP
   S: 265  LqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           L F+Tgs+r+P+ G+++lk    vi+   + ++ lP ++TCfn+L+LP+Ys+ke+l++kL+ Ai++ +gF+l
   Q: 975  LLFLTGSDRIPILGMKSLK---LVIQPtGGGEQFLPVAHTCFNLLDLPKYSKKETLRSKLIQAIDHYEGFSL 1043
           *******************...6666658899**************************************97 PP
   
Organism Xenopus tropicalis
Protein Sequence
(Fasta)
MLCWGNTSFG QLGLGGIDEE VVLEPRRCDF FINKNVRDVG CGSSTHSFFT LGSKLLNCIV 60
SLLSTVQFNS LSFYAEQVGA LDAQIIVAVS CGEAHTLALN DKGQVFSWGH AVYGQIGLST 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Xtr-132719|E3,HECT|Xenopus tropicalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTTATGCT GGGGAAATAC ATCTTTTGGA CAGCTGGGAT TAGGGGGGAT TGATGAGGAG 60
GTTGTTTTAG AACCGAGAAG ATGTGACTTT TTCATCAATA AAAATGTCCG TGATGTCGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-132719|E3,HECT|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3
Pfam

PF00632--HECT
PF00415--RCC1
PRINTS

PR00633--RCCNDNSATION
SMART

SM00119--HECTc
Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001666 Ailuropoda melanoleuca 70.70 0.00e+00 1397.00
IUUC-Apl-003295 Anas platyrhynchos 71.21 0.00e+00 1431.00
IUUC-Aca-004336 Anolis carolinensis 70.55 0.00e+00 1429.00
IUUC-Ame-010768 Astyanax mexicanus 63.59 0.00e+00 1293.00
IUUC-Bta-013279 Bos taurus 70.79 0.00e+00 1392.00
IUUC-Cja-019023 Callithrix jacchus 71.32 0.00e+00 1398.00
IUUC-Cfa-021074 Canis familiaris 70.60 0.00e+00 1394.00
IUUC-Cpo-021461 Cavia porcellus 70.66 0.00e+00 1390.00
IUUC-Csa-024261 Chlorocebus sabaeus 71.20 0.00e+00 1395.00
IUUC-Cin-025232 Ciona intestinalis 39.44 0.00e+00 687.00
IUUC-Dre-028829 Danio rerio 65.38 0.00e+00 1287.00
IUUC-Dno-029445 Dasypus novemcinctus 71.48 0.00e+00 1173.00
IUUC-Dor-030158 Dipodomys ordii 81.98 0.00e+00 756.00
IUUC-Dme-032103 Drosophila melanogaster 41.26 0.00e+00 758.00
IUUC-Ete-033072 Echinops telfairi 64.28 0.00e+00 1228.00
IUUC-Eca-033317 Equus caballus 69.85 0.00e+00 1377.00
IUUC-Fca-035682 Felis catus 71.24 0.00e+00 1404.00
IUUC-Fal-036969 Ficedula albicollis 69.87 0.00e+00 1419.00
IUUC-Gmo-038671 Gadus morhua 64.01 0.00e+00 1283.00
IUUC-Gga-041174 Gallus gallus 70.81 0.00e+00 1428.00
IUUC-Gac-042600 Gasterosteus aculeatus 63.64 0.00e+00 1235.00
IUUC-Ggo-044589 Gorilla gorilla 70.60 0.00e+00 1404.00
IUUC-Hsa-046772 Homo sapiens 70.60 0.00e+00 1399.00
IUUC-Lch-050147 Latimeria chalumnae 66.70 0.00e+00 1105.00
IUUC-Loc-052684 Lepisosteus oculatus 67.30 0.00e+00 1335.00
IUUC-Laf-053844 Loxodonta africana 70.32 0.00e+00 1386.00
IUUC-Mcc-055531 Macaca mulatta 69.59 0.00e+00 1384.00
IUUC-Mga-060151 Meleagris gallopavo 67.11 0.00e+00 1112.00
IUUC-Mmr-060954 Microcebus murinus 70.70 0.00e+00 1393.00
IUUC-Mdo-062246 Monodelphis domestica 72.72 0.00e+00 1342.00
IUUC-Mmu-063369 Mus musculus 70.95 0.00e+00 1418.00
IUUC-Mpu-065936 Mustela putorius furo 72.23 0.00e+00 1327.00
IUUC-Mlu-067326 Myotis lucifugus 70.60 0.00e+00 1363.00
IUUC-Nle-069453 Nomascus leucogenys 71.24 0.00e+00 1400.00
IUUC-Opr-071135 Ochotona princeps 68.95 0.00e+00 667.00
IUUC-Ont-071720 Oreochromis niloticus 65.28 0.00e+00 1285.00
IUUC-Oan-073464 Ornithorhynchus anatinus 71.72 0.00e+00 1327.00
IUUC-Ocu-074207 Oryctolagus cuniculus 70.26 0.00e+00 1311.00
IUUC-Ola-086762 Oryzias latipes 65.27 0.00e+00 1276.00
IUUC-Oga-088435 Otolemur garnettii 70.98 0.00e+00 1398.00
IUUC-Oar-089233 Ovis aries 70.60 0.00e+00 1390.00
IUUC-Ptr-091368 Pan troglodytes 70.79 0.00e+00 1404.00
IUUC-Pan-092300 Papio anubis 71.20 0.00e+00 1395.00
IUUC-Psi-093406 Pelodiscus sinensis 71.43 0.00e+00 1438.00
IUUC-Pma-094113 Petromyzon marinus 64.13 0.00e+00 934.00
IUUC-Ppa-095354 Physcomitrella patens 30.11 5.00e-126 445.00
IUUC-Pfo-097021 Poecilia formosa 64.08 0.00e+00 1303.00
IUUC-Pab-098327 Pongo abelii 70.79 0.00e+00 1407.00
IUUC-Pca-101075 Procavia capensis 75.87 1.00e-169 590.00
IUUC-Pva-102909 Pteropus vampyrus 62.29 0.00e+00 1174.00
IUUC-Rno-105457 Rattus norvegicus 70.23 0.00e+00 1406.00
IUUC-Sha-106632 Sarcophilus harrisii 71.14 0.00e+00 1418.00
IUUC-Sar-113679 Sorex araneus 61.84 0.00e+00 771.00
IUUC-Tgu-116849 Taeniopygia guttata 66.29 0.00e+00 1307.00
IUUC-Tru-118206 Takifugu rubripes 63.54 0.00e+00 1205.00
IUUC-Tsy-119521 Tarsius syrichta 58.88 0.00e+00 1107.00
IUUC-Tni-120233 Tetraodon nigroviridis 63.95 0.00e+00 1232.00
IUUC-Tbe-127941 Tupaia belangeri 71.81 0.00e+00 872.00
IUUC-Vpa-130448 Vicugna pacos 70.51 0.00e+00 1385.00
IUUC-Xma-133389 Xiphophorus maculatus 64.16 0.00e+00 1305.00
Created Date 25-Jun-2017

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