iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003567

Ensembl Protein ID

ENSAPLP00000004164.1

UniProt Accession

U3IA93; U3IA93_ANAPL

Genbank Protein ID

ENSAPLP00000004164

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01136496

Gene Name

OTUD7B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000004627.1	ENSAPLT00000004773.1	ENSAPLP00000004164.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.90e-37	128.5	169	350

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++ l++ + + +++++ k+++++++++++k           ++e++++ kl+++e    
   Q: 169  LPLATTGDGNCLLHAASLGMWGFHDRDLmLRKSLYTLMDKGVEREALKRRWRWQQTQQNKesglvyteeewQKEWNELIKLASSEprvh 257
           6899*********************************************************************************8877 PP
   S: 75   ..akg.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYda 134
             + g                 ee+h+f+La++L+rpi+vv++++l++         ++ggi+lpl++p++k +++p+vL+Y+++H++a
   Q: 258  ygTNGgncggvesseepvyeslEEFHVFVLAHVLKRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPANKcHRSPLVLAYDQAHFSA 346
           7522367788******************************************************************************* PP
   S: 135  Lval 138
           Lv++
   Q: 347  LVSM 350
           *986 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

TALAMDIVLS DFVRSTGAEP GLARDLLEGK NWDLSAALSD FEQLRQVHAG NLPPSFNEGR 60
SYKPPEKEAX PLQRQDDIVQ EKRLSRGISH ASSTIVSLAR SHVSSNGSSE HLLEMPISTF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGGCCTTGG CTATGGACAT CGTCCTGTCG GATTTTGTTC GCTCAACGGG GGCAGAGCCG 60
GGACTGGCCA GAGACCTGCT GGAAGGTAAA TAAAGCNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0002385--P:mucosal immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032717--P:negative regulation of interleukin-8 production
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035871--P:protein K11-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002119	Ailuropoda melanoleuca	68.32	0.00e+00	981.00
IUUC-Ani-009320	Aspergillus nidulans	50.00	6.60e-02	32.30
IUUC-Bta-013398	Bos taurus	66.78	0.00e+00	951.00
IUUC-Cel-018468	Caenorhabditis elegans	50.17	3.00e-85	308.00
IUUC-Cja-019965	Callithrix jacchus	68.28	0.00e+00	1007.00
IUUC-Cfa-020191	Canis familiaris	68.70	0.00e+00	981.00
IUUC-Cpo-022232	Cavia porcellus	67.38	0.00e+00	925.00
IUUC-Csa-023593	Chlorocebus sabaeus	68.55	0.00e+00	1041.00
IUUC-Csv-026177	Ciona savignyi	33.90	2.00e-03	35.40
IUUC-Dno-029900	Dasypus novemcinctus	66.94	0.00e+00	948.00
IUUC-Dor-031121	Dipodomys ordii	74.54	1.00e-176	612.00
IUUC-Ete-032473	Echinops telfairi	70.85	0.00e+00	832.00
IUUC-Eca-033946	Equus caballus	75.56	0.00e+00	855.00
IUUC-Eeu-034670	Erinaceus europaeus	66.87	0.00e+00	945.00
IUUC-Fca-035871	Felis catus	66.55	0.00e+00	949.00
IUUC-Gmo-039373	Gadus morhua	81.82	0.00e+00	710.00
IUUC-Gga-041105	Gallus gallus	86.89	0.00e+00	1300.00
IUUC-Gac-041806	Gasterosteus aculeatus	60.90	0.00e+00	855.00
IUUC-Ggo-045472	Gorilla gorilla	67.63	0.00e+00	1002.00
IUUC-Hsa-046473	Homo sapiens	67.63	0.00e+00	1009.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	68.76	0.00e+00	984.00
IUUC-Lch-050432	Latimeria chalumnae	70.08	0.00e+00	1077.00
IUUC-Mcc-055261	Macaca mulatta	68.47	0.00e+00	1040.00
IUUC-Meu-056477	Macropus eugenii	66.98	0.00e+00	798.00
IUUC-Mga-059533	Meleagris gallopavo	83.76	0.00e+00	1229.00
IUUC-Mdo-062847	Monodelphis domestica	69.62	0.00e+00	996.00
IUUC-Mmu-064260	Mus musculus	66.51	0.00e+00	900.00
IUUC-Mpu-066876	Mustela putorius furo	64.43	0.00e+00	887.00
IUUC-Mlu-068039	Myotis lucifugus	67.01	0.00e+00	982.00
IUUC-Nle-069260	Nomascus leucogenys	67.43	0.00e+00	1011.00
IUUC-Opr-070564	Ochotona princeps	80.68	0.00e+00	685.00
IUUC-Ocu-073824	Oryctolagus cuniculus	81.09	0.00e+00	827.00
IUUC-Ola-086490	Oryzias latipes	56.50	0.00e+00	844.00
IUUC-Oga-088124	Otolemur garnettii	66.43	0.00e+00	961.00
IUUC-Oar-090086	Ovis aries	67.30	0.00e+00	955.00
IUUC-Ptr-091622	Pan troglodytes	75.54	0.00e+00	907.00
IUUC-Pan-092724	Papio anubis	68.70	0.00e+00	1033.00
IUUC-Psi-093333	Pelodiscus sinensis	77.77	0.00e+00	1176.00
IUUC-Pab-098667	Pongo abelii	67.81	0.00e+00	1001.00
IUUC-Pva-102136	Pteropus vampyrus	67.54	0.00e+00	954.00
IUUC-Rno-105546	Rattus norvegicus	67.17	0.00e+00	924.00
IUUC-Sha-106732	Sarcophilus harrisii	67.58	0.00e+00	899.00
IUUC-Sar-113562	Sorex araneus	60.34	0.00e+00	773.00
IUUC-Ssc-116191	Sus scrofa	67.26	0.00e+00	974.00
IUUC-Tgu-116942	Taeniopygia guttata	91.39	0.00e+00	965.00
IUUC-Tru-117911	Takifugu rubripes	79.78	0.00e+00	741.00
IUUC-Tsy-119343	Tarsius syrichta	69.30	0.00e+00	874.00
IUUC-Tbe-127283	Tupaia belangeri	81.68	0.00e+00	692.00
IUUC-Ttr-128692	Tursiops truncatus	63.39	0.00e+00	857.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence