iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097823

Ensembl Protein ID

ENSPPYP00000008754.2

UniProt Accession

H2NS47; H2NS47_PONAB

Genbank Protein ID

ENSPPYP00000008754

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01345144

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000007770.2	ENSPPYT00000009112.2	ENSPPYP00000008754.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-13	50.1	134	189

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 134  AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 189
           689*************************..6999******9.5**************98 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS VSENSRVSHY 60
IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL LEFYKIHYLD TTTLIEPVSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTCATTTC CGGTGGGGAA GGCCCGCGGC TGCCGCCGCC ATTTCGGGCG CTGCTGTGAA 60
GCTGAAACCG GAGCCGGTCC GCTGGGCGGC GGGCGCCGGG GGCCGGAGGG GCGCGCGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	99.49	4.00e-97	347.00
IUUC-Apl-003225	Anas platyrhynchos	87.90	9.00e-62	229.00
IUUC-Ame-011721	Astyanax mexicanus	71.50	9.00e-79	286.00
IUUC-Bta-012320	Bos taurus	100.00	2.00e-100	358.00
IUUC-Cel-018307	Caenorhabditis elegans	33.16	7.00e-20	90.90
IUUC-Cja-019935	Callithrix jacchus	94.58	1.00e-104	372.00
IUUC-Cfa-021221	Canis familiaris	99.51	2.00e-100	359.00
IUUC-Cpo-021592	Cavia porcellus	80.00	2.00e-76	278.00
IUUC-Csa-024128	Chlorocebus sabaeus	100.00	4.00e-101	359.00
IUUC-Cho-024775	Choloepus hoffmanni	96.55	3.00e-99	354.00
IUUC-Dre-027390	Danio rerio	72.14	2.00e-79	288.00
IUUC-Dno-029847	Dasypus novemcinctus	100.00	2.00e-100	358.00
IUUC-Dor-030360	Dipodomys ordii	85.22	2.00e-95	342.00
IUUC-Ete-032604	Echinops telfairi	97.54	5.00e-66	243.00
IUUC-Eca-033233	Equus caballus	97.54	1.00e-99	355.00
IUUC-Eeu-034642	Erinaceus europaeus	95.08	1.00e-65	242.00
IUUC-Fca-035955	Felis catus	99.19	1.00e-68	252.00
IUUC-Fal-037152	Ficedula albicollis	82.78	2.00e-80	292.00
IUUC-Gmo-038849	Gadus morhua	70.92	1.00e-78	286.00
IUUC-Gga-040861	Gallus gallus	78.43	3.00e-89	321.00
IUUC-Gac-041627	Gasterosteus aculeatus	67.63	8.00e-80	290.00
IUUC-Ggo-045475	Gorilla gorilla	100.00	2.00e-100	358.00
IUUC-Hsa-046008	Homo sapiens	100.00	2.00e-100	358.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	99.51	3.00e-99	354.00
IUUC-Lch-050509	Latimeria chalumnae	77.51	1.00e-88	319.00
IUUC-Loc-052229	Lepisosteus oculatus	68.75	4.00e-83	300.00
IUUC-Laf-053896	Loxodonta africana	92.72	6.00e-104	370.00
IUUC-Mcc-055280	Macaca mulatta	100.00	2.00e-100	358.00
IUUC-Meu-056783	Macropus eugenii	96.72	5.00e-66	243.00
IUUC-Mdo-062691	Monodelphis domestica	84.06	4.00e-93	334.00
IUUC-Mmu-063691	Mus musculus	99.51	4.00e-100	357.00
IUUC-Mpu-065737	Mustela putorius furo	99.51	2.00e-100	358.00
IUUC-Mlu-067005	Myotis lucifugus	95.57	3.00e-96	344.00
IUUC-Nle-070154	Nomascus leucogenys	99.19	2.00e-68	251.00
IUUC-Opr-071114	Ochotona princeps	98.03	2.00e-113	401.00
IUUC-Ont-071696	Oreochromis niloticus	72.36	4.00e-77	281.00
IUUC-Oan-072967	Ornithorhynchus anatinus	92.61	3.00e-99	354.00
IUUC-Ocu-074025	Oryctolagus cuniculus	99.02	5.00e-100	356.00
IUUC-Ola-087265	Oryzias latipes	71.72	9.00e-78	283.00
IUUC-Oga-088266	Otolemur garnettii	98.03	2.00e-99	355.00
IUUC-Oar-089221	Ovis aries	97.55	6.00e-96	343.00
IUUC-Ptr-091463	Pan troglodytes	93.10	1.00e-88	319.00
IUUC-Pan-092242	Papio anubis	99.51	2.00e-100	358.00
IUUC-Psi-093287	Pelodiscus sinensis	92.68	3.00e-65	241.00
IUUC-Pfo-097378	Poecilia formosa	67.35	3.00e-72	264.00
IUUC-Pca-101068	Procavia capensis	100.00	2.00e-100	358.00
IUUC-Rno-105288	Rattus norvegicus	100.00	2.00e-100	358.00
IUUC-Sar-113453	Sorex araneus	76.85	3.00e-84	304.00
IUUC-Tgu-116926	Taeniopygia guttata	82.84	4.00e-89	321.00
IUUC-Tru-117806	Takifugu rubripes	72.12	4.00e-78	284.00
IUUC-Tni-120497	Tetraodon nigroviridis	71.50	4.00e-75	274.00
IUUC-Tbe-127436	Tupaia belangeri	98.99	2.00e-95	341.00
IUUC-Ttr-129109	Tursiops truncatus	100.00	1.00e-67	249.00
IUUC-Vpa-130527	Vicugna pacos	100.00	2.00e-100	358.00
IUUC-Xtr-131808	Xenopus tropicalis	79.41	5.00e-90	323.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence