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Tag Content
UUCD2 ID IUUC-Oga-088297
UUCD1 version UUC-OtG-00765
Ensembl Protein ID ENSOGAP00000003526.2
UniProt Accession H0WNV0; H0WNV0_OTOGA
Genbank Protein ID ENSOGAP00000003526
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAQR03163964
Gene Name USP19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000003957.2 ENSOGAT00000003963.2 ENSOGAP00000003526.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.50e-115 384.4 596 1313
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl NlgNtC+mNSv+Q+Lsn++elr+++++ +++ ++n +np ++ g+l+  ++ l+++lwk++++a++p++l+++++++a++f+g
   Q: 596  TGLVNLGNTCFMNSVIQSLSNTRELRDFFHDrSFEAEINYNNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTG 682
           7*****************************999****************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d   ++de     a++++k++n+s+i+dlFqgq+ks+++c+ c++vs +++p
   Q: 683  YAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSD--GRPDEvvaeeAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDP 767
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           fl+l++p+p+k++  +                                                                       
   Q: 768  FLYLPVPLPQKQKVLPVfyfarephskpikflvsvskenssasevldslsqsvhvkpenlrlaeviknrfhrvflpshsldtvspsd 854
           ************87666********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 855  tllcfellspelakervvvlevqqrpqvpsipiskcaacqrkqqsedeklkrctrcyrvgycnqlcqkthwpdhkglcrpenigypf 941
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 942  lvsvpasrltyarlaqllegyarysvsvfqppfqpgrialesqgpgcttllstnsleagdserdsiqppelqlvtpvaegdtgvprv 1028
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1029 waapdrgpgpstsgisseiltsgpielgslaacervsrpeaavpgyqhpseamnahtpqffiykidasnreqrledkgetplelgdd 1115
           *************************************************************************************** PP
   S: 186  ..........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevL 230
                                                     +l++cL+ ft++e l  e+++yc++ck+++ea+k+l l++lP+vL
   Q: 1116 cslalvwrnnerlpefvlvaskelecaedpgsageaaraghfTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVL 1202
           *************************************************************************************** PP
   S: 231  ilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk........Wll 308
           i++LkRfsf++  +++ kin+ vefp + Ldls+fc+ ++e+q    +Y+L+av++H+G++ +GHY+a+++  +++        W l
   Q: 1203 IVQLKRFSFRSFIWRD-KINDLVEFPVRnLDLSKFCIGQKEEQ--LPSYDLYAVINHYGGMIGGHYTACARLPNDRssqrsdvgWRL 1286
           ************8886.**********9**********99888..9**************************544445566777*** PP
   S: 309  fdDskVtevkeeevleetgstaYvlfYkrr 338
           fdDs+Vt+v+e++v++   + aYvlfY+rr
   Q: 1287 FDDSTVTTVDESQVVT---RYAYVLFYRRR 1313
           ****************...********996 PP
   
Organism Otolemur garnettii
Protein Sequence
(Fasta)
MSGGASATGQ RRGPPGLEEG TCKKKQKDRA NQESKDGDPR KGGSNFLDSL ASALKSGYLT 60
EIQKMIDGVM GSWTLSPIVV SLFFPSSSGS VSTPREEQNK EGACDLFATP PTELLLDWRQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oga-088297|DUB,USP|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCTGGTG GGGCCAGTGC CACAGGCCAG AGGAGAGGGC CCCCAGGACT GGAGGAGGGT 60
ACTTGTAAAA AGAAACAGAA GGATCGAGCA AACCAGGAGA GCAAGGATGG AGATCCTAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oga-088297|DUB,USP|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR007052--CS_dom
IPR008978--HSP20-like_chaperone
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND
PROSITE

PS51203--CS
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2
Pfam

PF04969--CS
PF00443--UCH
PF01753--zf-MYND
Gene Ontology

GO:0005829--C:cytosol
GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0046872--F:metal ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1901799--P:negative regulation of proteasomal protein catabolic process
GO:0048642--P:negative regulation of skeletal muscle tissue development
GO:0050821--P:protein stabilization
GO:1900037--P:regulation of cellular response to hypoxia
GO:1904292--P:regulation of ERAD pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001999 Ailuropoda melanoleuca 90.38 0.00e+00 2305.00
IUUC-Apl-003368 Anas platyrhynchos 67.00 0.00e+00 1703.00
IUUC-Aca-004267 Anolis carolinensis 67.50 0.00e+00 1628.00
IUUC-Ame-010970 Astyanax mexicanus 69.65 0.00e+00 1335.00
IUUC-Bta-012905 Bos taurus 89.18 0.00e+00 2297.00
IUUC-Cel-018257 Caenorhabditis elegans 43.48 3.00e-91 330.00
IUUC-Cja-018789 Callithrix jacchus 90.79 0.00e+00 2422.00
IUUC-Cfa-021004 Canis familiaris 90.10 0.00e+00 2306.00
IUUC-Cpo-021529 Cavia porcellus 86.76 0.00e+00 2327.00
IUUC-Csa-024035 Chlorocebus sabaeus 93.20 0.00e+00 2257.00
IUUC-Cho-025036 Choloepus hoffmanni 80.62 0.00e+00 1222.00
IUUC-Cin-025451 Ciona intestinalis 43.93 1.00e-86 315.00
IUUC-Csv-025931 Ciona savignyi 36.44 3.00e-110 392.00
IUUC-Dre-028556 Danio rerio 68.72 0.00e+00 1317.00
IUUC-Dno-029240 Dasypus novemcinctus 89.55 0.00e+00 2118.00
IUUC-Dor-030495 Dipodomys ordii 95.11 0.00e+00 1244.00
IUUC-Ete-032741 Echinops telfairi 91.90 0.00e+00 1860.00
IUUC-Eca-033661 Equus caballus 90.61 0.00e+00 2390.00
IUUC-Eeu-034648 Erinaceus europaeus 91.24 0.00e+00 825.00
IUUC-Fca-035646 Felis catus 89.87 0.00e+00 2280.00
IUUC-Fal-037094 Ficedula albicollis 68.76 0.00e+00 1740.00
IUUC-Gmo-038869 Gadus morhua 72.04 0.00e+00 842.00
IUUC-Gga-041170 Gallus gallus 65.87 0.00e+00 1695.00
IUUC-Gac-041901 Gasterosteus aculeatus 66.43 0.00e+00 1326.00
IUUC-Ggo-044708 Gorilla gorilla 91.29 0.00e+00 2439.00
IUUC-Hsa-046791 Homo sapiens 95.11 0.00e+00 2062.00
IUUC-Itr-048892 Ictidomys tridecemlineatus 89.30 0.00e+00 2333.00
IUUC-Lch-050456 Latimeria chalumnae 51.02 0.00e+00 1180.00
IUUC-Loc-052861 Lepisosteus oculatus 62.36 0.00e+00 1139.00
IUUC-Laf-053788 Loxodonta africana 88.45 0.00e+00 2294.00
IUUC-Mcc-055693 Macaca mulatta 89.92 0.00e+00 2365.00
IUUC-Meu-055921 Macropus eugenii 78.91 0.00e+00 1524.00
IUUC-Mga-059879 Meleagris gallopavo 65.66 0.00e+00 1744.00
IUUC-Mmr-060802 Microcebus murinus 94.28 0.00e+00 2524.00
IUUC-Mdo-061856 Monodelphis domestica 79.18 0.00e+00 1620.00
IUUC-Mmu-063874 Mus musculus 87.47 0.00e+00 2326.00
IUUC-Mpu-066166 Mustela putorius furo 91.05 0.00e+00 2318.00
IUUC-Nle-070161 Nomascus leucogenys 91.22 0.00e+00 2483.00
IUUC-Opr-071015 Ochotona princeps 92.82 0.00e+00 1934.00
IUUC-Ont-072308 Oreochromis niloticus 69.31 0.00e+00 1363.00
IUUC-Oan-072723 Ornithorhynchus anatinus 66.47 0.00e+00 1594.00
IUUC-Ocu-073938 Oryctolagus cuniculus 90.69 0.00e+00 2290.00
IUUC-Ola-086375 Oryzias latipes 69.65 0.00e+00 1333.00
IUUC-Oar-089675 Ovis aries 94.80 0.00e+00 1647.00
IUUC-Ptr-091621 Pan troglodytes 94.76 0.00e+00 2057.00
IUUC-Pan-092118 Papio anubis 90.67 0.00e+00 2370.00
IUUC-Pma-094154 Petromyzon marinus 51.78 5.00e-114 405.00
IUUC-Pfo-097246 Poecilia formosa 60.27 0.00e+00 1397.00
IUUC-Pab-098551 Pongo abelii 94.13 0.00e+00 2035.00
IUUC-Pca-100158 Procavia capensis 84.64 0.00e+00 2264.00
IUUC-Pva-103160 Pteropus vampyrus 89.58 0.00e+00 2321.00
IUUC-Rno-105355 Rattus norvegicus 87.65 0.00e+00 2343.00
IUUC-Sha-107057 Sarcophilus harrisii 72.42 0.00e+00 1841.00
IUUC-Sar-113011 Sorex araneus 90.11 0.00e+00 1511.00
IUUC-Ssc-115761 Sus scrofa 89.63 0.00e+00 2341.00
IUUC-Tgu-116956 Taeniopygia guttata 61.24 0.00e+00 832.00
IUUC-Tru-118739 Takifugu rubripes 69.46 0.00e+00 1352.00
IUUC-Tsy-118827 Tarsius syrichta 81.39 0.00e+00 1247.00
IUUC-Tni-119921 Tetraodon nigroviridis 61.09 0.00e+00 1391.00
IUUC-Tbe-128017 Tupaia belangeri 91.85 0.00e+00 1974.00
IUUC-Ttr-128869 Tursiops truncatus 88.16 0.00e+00 2300.00
IUUC-Vpa-130427 Vicugna pacos 95.30 0.00e+00 924.00
IUUC-Xtr-132734 Xenopus tropicalis 61.34 0.00e+00 1560.00
Created Date 25-Jun-2017

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