iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cgl-026642

Ensembl Protein ID

ELA35440

UniProt Accession

L2GAN2; L2GAN2_COLGN

Genbank Protein ID

ELA35440.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

KB020568

Gene Name

CGGC5_4839

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CGGC5_4839	ELA35440	ELA35440

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.40e-125	418.8	483	815

Active Site

Position(s)	Description	Evidence
784	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllg 102
           + dlkkrl+++f gE+gld+gG++ref++lls+e++np ++lf+ys+ d++tlq+np+sg+ npehl++F+f+Gr++g+a++++r+ld+++  ++yk++lg
   Q: 483  ATDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGI-NPEHLNYFKFIGRVVGLAIFHRRFLDAFFIGALYKMILG 582
           579*********************************************************9.89************************************* PP
   S: 103  kklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnevipl 203
           k++ l d+e vd+++++sl+++++n   di+   l+ tfs+++e +g +++e+L+p+G+ni+VtneNk+eYv+l+v++r++++i+eq++af++Gf+e+ip+
   Q: 583  KSVVLADMEGVDADFHRSLQWMLDN---DISGGILEQTFSTEDERFGVMTVEDLIPNGRNIDVTNENKKEYVDLMVKWRIEKRIAEQFQAFKDGFHELIPQ 680
           ***********************99...9************************************************************************ PP
   S: 204  ellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirkdasddrlPs 300
           +l+++F+e+elelli G +eidv+d+kk+t y+g yte++++iq+Fw+++++++ e+++++LqF+Tg+sr+P++Gf++l+    pr+f+i+k+++ ++lP+
   Q: 681  DLINVFDERELELLIGGIAEIDVDDWKKHTDYRG-YTESDEVIQFFWQTIRSWDGEQKSRLLQFATGTSRIPVNGFKDLQgsdgPRRFTIEKAGEINNLPK 780
           ********************************76.*********************************************************9999***** PP
   S: 301  snTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           ++TCfn+L+LP+Y+s e l++kL++A+eet gF++
   Q: 781  AHTCFNRLDLPPYKSLEMLQQKLTIAVEETMGFGQ 815
           *********************************96 PP

Organism

Colletotrichum gloeosporioides

Protein Sequence
(Fasta)

MSSSRNDAGQ PNRKPNLRVT IIAADGLYKR DVFRFPDPFA VITVNGDQTK TTTAQKRTLN 60
PYWNESFDLH VNEDTILAVQ VFDQKKFKKK DQGFLGVINV RIGDVIELAP DADDQMLTRD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTTCCT CCCGCAATGA TGCCGGGCAA CCCAAGTAAG TTCGCTCCTG CTTGGCCGGA 60
CCCATCTTCA TGGACTCTGG TCATTCCGAT GTCATCAAAG CCGGGAAGCA TAACGATAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR024928--E3_ub_ligase_SMURF1
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001314	Ailuropoda melanoleuca	47.51	1.00e-151	528.00
IUUC-Apl-003752	Anas platyrhynchos	49.40	3.00e-158	550.00
IUUC-Aca-005338	Anolis carolinensis	47.51	7.00e-156	542.00
IUUC-Ago-007742	Ashbya gossypii	64.63	0.00e+00	989.00
IUUC-Acl-008273	Aspergillus clavatus	73.06	0.00e+00	1107.00
IUUC-Afl-008713	Aspergillus flavus	71.98	0.00e+00	1117.00
IUUC-Afu-009103	Aspergillus fumigatus	71.22	0.00e+00	1087.00
IUUC-Ani-009259	Aspergillus nidulans	70.94	0.00e+00	1117.00
IUUC-Ang-009738	Aspergillus niger	71.72	0.00e+00	1135.00
IUUC-Aor-010053	Aspergillus oryzae	77.33	2.00e-141	493.00
IUUC-Ate-010529	Aspergillus terreus	73.67	0.00e+00	1120.00
IUUC-Ame-011081	Astyanax mexicanus	47.08	1.00e-153	535.00
IUUC-Bgr-012148	Blumeria graminis	76.22	0.00e+00	1178.00
IUUC-Bta-012679	Bos taurus	47.51	9.00e-152	529.00
IUUC-Bci-013785	Botrytis cinerea	78.21	0.00e+00	1246.00
IUUC-Cel-018299	Caenorhabditis elegans	43.59	7.00e-144	502.00
IUUC-Cja-018732	Callithrix jacchus	47.34	4.00e-151	526.00
IUUC-Cfa-021226	Canis familiaris	47.51	7.00e-152	529.00
IUUC-Cpo-021671	Cavia porcellus	47.51	7.00e-152	529.00
IUUC-Csa-023252	Chlorocebus sabaeus	47.71	8.00e-157	545.00
IUUC-Cho-024695	Choloepus hoffmanni	48.71	3.00e-158	550.00
IUUC-Cin-025212	Ciona intestinalis	45.36	8.00e-147	512.00
IUUC-Csv-026256	Ciona savignyi	44.06	2.00e-141	494.00
IUUC-Cne-026849	Cryptococcus neoformans	59.33	0.00e+00	967.00
IUUC-Dre-028245	Danio rerio	47.16	2.00e-153	534.00
IUUC-Dno-029466	Dasypus novemcinctus	47.51	6.00e-152	530.00
IUUC-Dor-030138	Dipodomys ordii	46.84	6.00e-147	513.00
IUUC-Dse-031241	Dothistroma septosporum	72.85	0.00e+00	1154.00
IUUC-Dme-032041	Drosophila melanogaster	43.79	1.00e-138	486.00
IUUC-Ete-032779	Echinops telfairi	44.17	8.00e-138	483.00
IUUC-Eca-033445	Equus caballus	47.51	2.00e-151	528.00
IUUC-Eeu-035247	Erinaceus europaeus	46.51	3.00e-150	524.00
IUUC-Fca-035605	Felis catus	48.05	1.00e-156	545.00
IUUC-Fal-037126	Ficedula albicollis	47.88	3.00e-156	543.00
IUUC-Fox-037774	Fusarium oxysporum	87.64	0.00e+00	1375.00
IUUC-Fso-038393	Fusarium solani	86.06	0.00e+00	1348.00
IUUC-Gmo-039674	Gadus morhua	46.58	5.00e-144	503.00
IUUC-Ggr-040107	Gaeumannomyces graminis	85.18	0.00e+00	1366.00
IUUC-Gga-040832	Gallus gallus	48.05	5.00e-157	546.00
IUUC-Gac-042020	Gasterosteus aculeatus	46.66	2.00e-146	511.00
IUUC-Ggo-045332	Gorilla gorilla	47.51	2.00e-151	528.00
IUUC-Hsa-045968	Homo sapiens	47.51	1.00e-151	528.00
IUUC-Itr-048918	Ictidomys tridecemlineatus	47.88	2.00e-156	545.00
IUUC-Kpa-049273	Komagataella pastoris	66.17	0.00e+00	1037.00
IUUC-Lch-050443	Latimeria chalumnae	47.34	7.00e-151	526.00
IUUC-Loc-052645	Lepisosteus oculatus	46.67	6.00e-151	526.00
IUUC-Lma-052980	Leptosphaeria maculans	70.24	0.00e+00	682.00
IUUC-Laf-054383	Loxodonta africana	48.05	3.00e-157	547.00
IUUC-Mcc-055821	Macaca mulatta	47.51	1.00e-151	528.00
IUUC-Meu-055953	Macropus eugenii	40.30	2.00e-115	408.00
IUUC-Mor-057097	Magnaporthe oryzae	86.92	0.00e+00	1405.00
IUUC-Mpo-057442	Magnaporthe poae	81.55	0.00e+00	1228.00
IUUC-Mla-058996	Melampsora laricipopulina	61.25	0.00e+00	998.00
IUUC-Mga-059661	Meleagris gallopavo	48.05	6.00e-157	546.00
IUUC-Mvi-060395	Microbotryum violaceum	77.23	0.00e+00	806.00
IUUC-Mmr-061135	Microcebus murinus	48.05	6.00e-157	546.00
IUUC-Mdo-062505	Monodelphis domestica	47.88	2.00e-156	544.00
IUUC-Mmu-064136	Mus musculus	47.51	7.00e-152	529.00
IUUC-Mpu-066203	Mustela putorius furo	48.22	3.00e-157	546.00
IUUC-Mlu-067837	Myotis lucifugus	48.22	3.00e-157	547.00
IUUC-Nfi-068427	Neosartorya fischeri	72.52	0.00e+00	1107.00
IUUC-Ncr-068918	Neurospora crassa	82.18	0.00e+00	1261.00
IUUC-Nle-069244	Nomascus leucogenys	48.05	8.00e-157	545.00
IUUC-Opr-071044	Ochotona princeps	46.51	4.00e-150	523.00
IUUC-Ont-072226	Oreochromis niloticus	46.68	1.00e-153	535.00
IUUC-Oan-073497	Ornithorhynchus anatinus	45.53	2.00e-150	524.00
IUUC-Ocu-074160	Oryctolagus cuniculus	46.43	6.00e-150	523.00
IUUC-Ola-087467	Oryzias latipes	46.76	8.00e-146	509.00
IUUC-Oga-088460	Otolemur garnettii	47.51	1.00e-151	528.00
IUUC-Oar-090198	Ovis aries	46.68	2.00e-151	528.00
IUUC-Ptr-090939	Pan troglodytes	47.51	1.00e-151	528.00
IUUC-Pan-092284	Papio anubis	47.51	1.00e-151	528.00
IUUC-Psi-093645	Pelodiscus sinensis	47.17	3.00e-152	531.00
IUUC-Pma-094364	Petromyzon marinus	50.50	2.00e-140	490.00
IUUC-Pno-095118	Phaeosphaeria nodorum	71.90	0.00e+00	1139.00
IUUC-Pfo-097145	Poecilia formosa	46.25	2.00e-143	501.00
IUUC-Pab-098088	Pongo abelii	47.51	2.00e-151	528.00
IUUC-Pca-100596	Procavia capensis	48.15	6.00e-134	469.00
IUUC-Pva-102354	Pteropus vampyrus	47.51	2.00e-151	528.00
IUUC-Pgr-103620	Puccinia graminis	66.72	0.00e+00	842.00
IUUC-Ptt-103806	Puccinia triticina	76.81	0.00e+00	682.00
IUUC-Pte-104016	Pyrenophora teres	72.32	0.00e+00	1150.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	72.32	0.00e+00	1150.00
IUUC-Rno-105318	Rattus norvegicus	47.51	7.00e-152	529.00
IUUC-Sce-106289	Saccharomyces cerevisiae	73.65	0.00e+00	901.00
IUUC-Sha-107175	Sarcophilus harrisii	47.88	1.00e-156	545.00
IUUC-Sja-107941	Schizosaccharomyces japonicus	65.30	0.00e+00	1029.00
IUUC-Spo-108171	Schizosaccharomyces pombe	67.08	0.00e+00	1032.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	78.43	0.00e+00	1244.00
IUUC-Stu-112894	Solanum tuberosum	34.71	4.00e-56	211.00
IUUC-Sar-113761	Sorex araneus	47.88	1.00e-155	541.00
IUUC-Sre-114929	Sporisorium reilianum	71.74	0.00e+00	883.00
IUUC-Ssc-115368	Sus scrofa	45.71	4.00e-149	520.00
IUUC-Tgu-117130	Taeniopygia guttata	47.18	7.00e-150	523.00
IUUC-Tru-118442	Takifugu rubripes	47.68	5.00e-156	543.00
IUUC-Tsy-119492	Tarsius syrichta	47.51	1.00e-150	525.00
IUUC-Tni-119993	Tetraodon nigroviridis	46.39	5.00e-146	509.00
IUUC-Tre-122203	Trichoderma reesei	83.91	0.00e+00	1302.00
IUUC-Tvi-122595	Trichoderma virens	82.77	0.00e+00	1331.00
IUUC-Tme-126897	Tuber melanosporum	69.64	0.00e+00	1059.00
IUUC-Tbe-127793	Tupaia belangeri	47.12	2.00e-129	455.00
IUUC-Ttr-128275	Tursiops truncatus	45.93	2.00e-145	507.00
IUUC-Uma-129332	Ustilago maydis	71.40	0.00e+00	857.00
IUUC-Vda-129753	Verticillium dahliae	87.35	0.00e+00	1353.00
IUUC-Vpa-130503	Vicugna pacos	50.52	2.00e-135	475.00
IUUC-Xtr-132859	Xenopus tropicalis	48.34	7.00e-153	532.00
IUUC-Xma-133797	Xiphophorus maculatus	47.19	3.00e-149	520.00
IUUC-Yli-134668	Yarrowia lipolytica	73.19	0.00e+00	932.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence