iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004549

Ensembl Protein ID

ENSACAP00000012299.3

UniProt Accession

H9GJ04; H9GJ04_ANOCA

Protein Name

Histone acetyltransferase

Gene Name

KAT6A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000012392.3	ENSACAT00000012551.3	ENSACAP00000012299.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.90e-10	39.1	264	313

Active Site

Position(s)	Description	Evidence
680	Proton donor/acceptor	{ECO:0000256\|PIRSR:PIRSR602717-51}

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           k C  C+++g++ ++++ C+ C++ fH +C  ++  + +p+   wiC+ Cr 
   Q: 264  KTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPP-LTRMPKGM-WICQICRP 313
           68999******99*********************.9*****97.******85 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MVKLANPLYT EWILEAIKKV KKQKQRPSEE RICNAVSSSH GLDRKTVLEQ LELSVKDGTI 60
LKVSNKGLNS YKDPDNPGRL ALPKPRNHGK LDGKPNVDWN KLIKRAVDGL AESSGSSLKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTATATTCCT TCTATTCACT TGTGGGTCTG ATTTGAACAT CAAGATCTGG AGTGAGATGT 60
ATTGAATTCT TTTCACTTAT GTTCTGTACC TATTTACTGG CTGTTTTTGG GATTTATTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR002717--HAT_MYST-type
IPR005818--Histone_H1/H5_H15
IPR031280--KAT6A
IPR015943--WD40/YVTN_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51504--H15
PS51726--MYST_HAT
PS50016--ZF_PHD_2

Pfam

PF01853--MOZ_SAS
PF00628--PHD

SMART

SM00526--H15
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0000786--C:nucleosome
GO:0016605--C:PML body
GO:0003677--F:DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0043966--P:histone H3 acetylation
GO:0030099--P:myeloid cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0006334--P:nucleosome assembly
GO:0045893--P:positive regulation of transcription, DNA-templated

KEGG

acs:100567099

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001219	Ailuropoda melanoleuca	75.52	0.00e+00	1722.00
IUUC-Ame-010711	Astyanax mexicanus	65.31	5.00e-173	602.00
IUUC-Bta-013426	Bos taurus	74.88	0.00e+00	1659.00
IUUC-Cja-019124	Callithrix jacchus	75.57	0.00e+00	1694.00
IUUC-Cfa-021165	Canis familiaris	76.39	0.00e+00	1728.00
IUUC-Cpo-022332	Cavia porcellus	69.10	0.00e+00	1332.00
IUUC-Cne-026801	Cryptococcus neoformans	63.59	2.00e-73	271.00
IUUC-Dre-028624	Danio rerio	76.62	0.00e+00	639.00
IUUC-Dno-029878	Dasypus novemcinctus	67.56	0.00e+00	1243.00
IUUC-Ete-032342	Echinops telfairi	78.47	0.00e+00	1575.00
IUUC-Eca-033925	Equus caballus	75.06	0.00e+00	1692.00
IUUC-Fca-035985	Felis catus	75.90	0.00e+00	1728.00
IUUC-Gmo-039182	Gadus morhua	72.95	0.00e+00	1158.00
IUUC-Gga-041028	Gallus gallus	78.88	0.00e+00	1798.00
IUUC-Gac-042131	Gasterosteus aculeatus	72.19	0.00e+00	1156.00
IUUC-Ggo-044664	Gorilla gorilla	75.81	0.00e+00	1672.00
IUUC-Hsa-046832	Homo sapiens	75.89	0.00e+00	1678.00
IUUC-Loc-052537	Lepisosteus oculatus	75.31	0.00e+00	1209.00
IUUC-Laf-053686	Loxodonta africana	76.03	0.00e+00	1711.00
IUUC-Mcc-055429	Macaca mulatta	76.13	0.00e+00	1682.00
IUUC-Mvi-060531	Microbotryum violaceum	55.80	8.00e-73	268.00
IUUC-Mmr-061249	Microcebus murinus	73.05	0.00e+00	1667.00
IUUC-Mdo-062826	Monodelphis domestica	89.21	0.00e+00	674.00
IUUC-Mmu-063474	Mus musculus	74.24	0.00e+00	1705.00
IUUC-Mpu-066585	Mustela putorius furo	76.09	0.00e+00	1711.00
IUUC-Mlu-066965	Myotis lucifugus	75.16	0.00e+00	1664.00
IUUC-Nle-069270	Nomascus leucogenys	75.89	0.00e+00	1674.00
IUUC-Opr-070963	Ochotona princeps	74.05	0.00e+00	1281.00
IUUC-Ont-071466	Oreochromis niloticus	69.21	2.00e-176	613.00
IUUC-Oan-073367	Ornithorhynchus anatinus	76.83	0.00e+00	1747.00
IUUC-Ocu-074100	Oryctolagus cuniculus	69.86	0.00e+00	1511.00
IUUC-Ola-087293	Oryzias latipes	72.19	0.00e+00	1157.00
IUUC-Oga-089052	Otolemur garnettii	86.91	0.00e+00	785.00
IUUC-Oar-089692	Ovis aries	84.44	0.00e+00	1508.00
IUUC-Ptr-091107	Pan troglodytes	75.99	0.00e+00	1668.00
IUUC-Pan-092524	Papio anubis	76.15	0.00e+00	1680.00
IUUC-Pfo-096641	Poecilia formosa	69.27	0.00e+00	1145.00
IUUC-Pab-098311	Pongo abelii	76.60	0.00e+00	1689.00
IUUC-Pca-100810	Procavia capensis	71.94	0.00e+00	1446.00
IUUC-Pgr-103522	Puccinia graminis	50.00	1.00e-68	254.00
IUUC-Pyt-104594	Pyrenophora triticirepentis	37.04	1.00e-46	181.00
IUUC-Rno-104990	Rattus norvegicus	74.30	0.00e+00	1636.00
IUUC-Sha-106816	Sarcophilus harrisii	76.39	0.00e+00	1739.00
IUUC-Sre-115066	Sporisorium reilianum	55.56	3.00e-78	286.00
IUUC-Tgu-116639	Taeniopygia guttata	77.91	0.00e+00	1791.00
IUUC-Tru-118571	Takifugu rubripes	71.82	0.00e+00	1175.00
IUUC-Tni-119936	Tetraodon nigroviridis	73.63	0.00e+00	1201.00
IUUC-Tbe-127928	Tupaia belangeri	91.92	0.00e+00	1497.00
IUUC-Uma-129445	Ustilago maydis	56.84	6.00e-80	292.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence