iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007748

Ensembl Protein ID

AAS51640

UniProt Accession

Q75BG8; Q75BG8_ASHGO

Genbank Protein ID

AAS51640.1

Protein Name

ADL280Wp

Genbank Nucleotide ID

AE016817

Gene Name

AGOS_ADL280W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_ADL280W	AAS51640	AAS51640

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.70e-89	296.0	599	933

Active Site

Position(s)	Description	Evidence
901	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg....EegldlgGvtreflallskelqnpd.lglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyk 98
           +d+k +l v+f +    E+g+d gG+t+efl+ +s+e +n+d + lf  ++n+ ++l+p+ ++   +p++l++ +flG++lgk+l+++ l+d++++ +f+ 
   Q: 599  EDFKDQLAVTFINefgpEAGIDGGGITKEFLTSVSDEGFNKDkYRLF--KANSVYELYPSDAAT--SPQQLQYLHFLGKVLGKCLYEKVLIDVHFADFFLH 695
           68999********999999*********************9989999..788899999999887..68********************************* PP
   S: 99   lllgk....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafre 195
           +ll++     +s+++l+++d+ely++l+++ ++  ++++ l+l +++  +    +++k +eL+pgG++ipVt +N ++Y  +v++yr++++ ++ +  f+ 
   Q: 696  KLLSTsknmACSFDNLPSFDRELYDNLNKLFDMSTAELQLLDLRMEIV-D---ENTMKIVELVPGGSQIPVTTTNVRQYALAVASYRMNSQLARATFYFQT 792
           ***997666699*******************99777777765555554.3...368999****************************************** PP
   S: 196  GfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd 295
           G+  +ip++++++F+ +el+ li+G  ++id+ dl+++ +y ggy e++p+iq +w+ l ef+ e+r++f++F+T+ +r+Pl Gf+ l+p+ f ir++++d
   Q: 793  GMAVIIPPHWIAIFSSSELSKLISGGgRDIDLADLRANVTY-GGYVESDPTIQHLWQLLLEFTPEQRCKFIKFATSVPRAPLLGFQMLNPK-FGIRNAGTD 891
           **************************9**************.78*********************************************88.999**9999 PP
   S: 296  .drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
            +rlP+++TC+n+LkLP+Y+ k+ l+ekLlyAi+++++F+ls
   Q: 892  yNRLPTASTCVNLLKLPDYQDKDLLREKLLYAINSEARFDLS 933
           9**************************************985 PP

Organism

Ashbya gossypii

Protein Sequence
(Fasta)

MLNFSGSTKR RNVNLGSSKK INKSELIEKA RLERERRAQE KRIQESTLCI QRCARRWTAR 60
RRVLGSLDGV AAREYGTQIL VAFGAGILHY ARGDAVAAVV EACSVDSATA YWRCTELLEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGAACT TCTCGGGGAG CACCAAGCGG CGGAATGTGA ATCTGGGGTC TTCAAAGAAG 60
ATTAACAAGA GCGAGTTGAT AGAGAAGGCG CGGTTGGAGC GGGAGAGGCG AGCACAGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0000502--C:proteasome complex
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0010994--P:free ubiquitin chain polymerization
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

ago:AGOS_ADL280W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	38.30	5.00e-71	261.00
IUUC-Aml-001355	Ailuropoda melanoleuca	42.08	2.00e-77	282.00
IUUC-Atr-003017	Amborella trichopoda	40.65	8.00e-78	283.00
IUUC-Apl-003731	Anas platyrhynchos	41.43	2.00e-80	291.00
IUUC-Aca-005248	Anolis carolinensis	41.19	3.00e-79	288.00
IUUC-Aly-005768	Arabidopsis lyrata	41.09	3.00e-75	275.00
IUUC-Ath-007269	Arabidopsis thaliana	38.59	8.00e-77	280.00
IUUC-Acl-008158	Aspergillus clavatus	37.61	1.00e-75	276.00
IUUC-Afl-008398	Aspergillus flavus	39.32	3.00e-80	291.00
IUUC-Afu-008937	Aspergillus fumigatus	38.46	4.00e-79	288.00
IUUC-Ani-009252	Aspergillus nidulans	38.17	5.00e-79	287.00
IUUC-Ang-009773	Aspergillus niger	36.97	1.00e-76	280.00
IUUC-Aor-009940	Aspergillus oryzae	39.32	3.00e-80	291.00
IUUC-Ate-010395	Aspergillus terreus	38.46	2.00e-80	292.00
IUUC-Ame-010769	Astyanax mexicanus	37.93	3.00e-60	224.00
IUUC-Bgr-012269	Blumeria graminis	39.39	2.00e-75	273.00
IUUC-Bta-012841	Bos taurus	42.08	1.00e-78	286.00
IUUC-Bci-013743	Botrytis cinerea	40.13	4.00e-84	304.00
IUUC-Bdi-014502	Brachypodium distachyon	39.01	6.00e-74	270.00
IUUC-Bol-015093	Brassica oleracea	38.77	1.00e-77	282.00
IUUC-Bra-016722	Brassica rapa	38.53	5.00e-77	280.00
IUUC-Cel-018447	Caenorhabditis elegans	31.19	1.00e-57	216.00
IUUC-Cja-019743	Callithrix jacchus	41.20	9.00e-76	276.00
IUUC-Cfa-021031	Canis familiaris	42.08	4.00e-78	284.00
IUUC-Cpo-022401	Cavia porcellus	41.67	9.00e-78	283.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	38.97	1.00e-69	254.00
IUUC-Csa-024107	Chlorocebus sabaeus	41.90	6.00e-78	283.00
IUUC-Cho-024750	Choloepus hoffmanni	43.19	2.00e-66	245.00
IUUC-Cin-025750	Ciona intestinalis	36.47	2.00e-64	238.00
IUUC-Csv-026016	Ciona savignyi	36.44	2.00e-66	244.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	37.86	4.00e-80	291.00
IUUC-Cne-026841	Cryptococcus neoformans	38.02	8.00e-70	256.00
IUUC-Cme-027265	Cyanidioschyzon merolae	41.11	2.00e-78	285.00
IUUC-Dre-028196	Danio rerio	41.90	7.00e-80	290.00
IUUC-Dno-029024	Dasypus novemcinctus	41.67	3.00e-78	284.00
IUUC-Dor-030938	Dipodomys ordii	38.60	2.00e-65	242.00
IUUC-Dse-031416	Dothistroma septosporum	38.09	2.00e-77	282.00
IUUC-Dme-031946	Drosophila melanogaster	37.35	9.00e-70	256.00
IUUC-Ete-033041	Echinops telfairi	37.03	1.00e-42	166.00
IUUC-Eca-033828	Equus caballus	41.67	1.00e-77	282.00
IUUC-Eeu-035201	Erinaceus europaeus	38.06	2.00e-43	168.00
IUUC-Fca-035907	Felis catus	41.90	4.00e-78	284.00
IUUC-Fal-037389	Ficedula albicollis	41.43	8.00e-80	290.00
IUUC-Fox-037788	Fusarium oxysporum	38.14	3.00e-76	278.00
IUUC-Fso-038088	Fusarium solani	39.02	8.00e-81	293.00
IUUC-Gmo-039412	Gadus morhua	36.38	3.00e-64	238.00
IUUC-Ggr-039941	Gaeumannomyces graminis	37.20	4.00e-82	297.00
IUUC-Gga-040310	Gallus gallus	41.19	2.00e-80	291.00
IUUC-Gac-042088	Gasterosteus aculeatus	35.17	2.00e-64	238.00
IUUC-Gma-043839	Glycine max	39.48	6.00e-75	273.00
IUUC-Ggo-045031	Gorilla gorilla	41.67	1.00e-77	282.00
IUUC-Hsa-045880	Homo sapiens	41.67	1.00e-77	282.00
IUUC-Hvu-047770	Hordeum vulgare	40.98	3.00e-75	274.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	39.30	2.00e-66	243.00
IUUC-Kpa-049307	Komagataella pastoris	36.77	5.00e-87	313.00
IUUC-Lch-050664	Latimeria chalumnae	33.60	2.00e-67	249.00
IUUC-Lpe-050755	Leersia perrieri	39.29	1.00e-72	265.00
IUUC-Loc-052218	Lepisosteus oculatus	41.90	4.00e-79	287.00
IUUC-Lma-053096	Leptosphaeria maculans	40.60	5.00e-87	314.00
IUUC-Laf-053902	Loxodonta africana	38.39	3.00e-68	251.00
IUUC-Mcc-055127	Macaca mulatta	41.67	2.00e-77	282.00
IUUC-Meu-056527	Macropus eugenii	41.40	8.00e-54	203.00
IUUC-Mor-057021	Magnaporthe oryzae	35.87	2.00e-69	255.00
IUUC-Mpo-057570	Magnaporthe poae	38.43	2.00e-82	298.00
IUUC-Mtr-058154	Medicago truncatula	40.71	1.00e-69	256.00
IUUC-Mla-059124	Melampsora laricipopulina	40.98	2.00e-73	267.00
IUUC-Mga-059581	Meleagris gallopavo	41.43	1.00e-80	292.00
IUUC-Mvi-060445	Microbotryum violaceum	35.17	3.00e-84	304.00
IUUC-Mmr-061360	Microcebus murinus	41.84	2.00e-77	282.00
IUUC-Mdo-062194	Monodelphis domestica	41.61	1.00e-78	286.00
IUUC-Mmu-064189	Mus musculus	41.67	7.00e-77	280.00
IUUC-Mac-065275	Musa acuminata	40.42	2.00e-76	278.00
IUUC-Mpu-066439	Mustela putorius furo	41.90	2.00e-78	285.00
IUUC-Mlu-068228	Myotis lucifugus	41.90	1.00e-78	286.00
IUUC-Nfi-068280	Neosartorya fischeri	38.46	4.00e-79	287.00
IUUC-Ncr-068869	Neurospora crassa	34.63	4.00e-75	274.00
IUUC-Nle-069687	Nomascus leucogenys	41.27	8.00e-77	280.00
IUUC-Opr-070554	Ochotona princeps	35.71	1.00e-66	246.00
IUUC-Ont-071836	Oreochromis niloticus	43.10	2.00e-81	295.00
IUUC-Oan-072800	Ornithorhynchus anatinus	41.43	1.00e-79	289.00
IUUC-Ocu-074587	Oryctolagus cuniculus	41.84	1.00e-77	282.00
IUUC-Oba-075006	Oryza barthii	41.31	4.00e-78	284.00
IUUC-Obr-076133	Oryza brachyantha	41.31	1.00e-77	283.00
IUUC-Ogl-077003	Oryza glaberrima	41.31	5.00e-78	283.00
IUUC-Ogu-078947	Oryza glumaepatula	39.87	2.00e-78	285.00
IUUC-Oin-080058	Oryza indica	39.34	2.00e-73	268.00
IUUC-Olo-080475	Oryza longistaminata	41.55	5.00e-78	283.00
IUUC-Ome-081741	Oryza meridionalis	38.12	9.00e-67	246.00
IUUC-Oni-082385	Oryza nivara	39.87	2.00e-78	285.00
IUUC-Opu-083176	Oryza punctata	41.55	1.00e-77	282.00
IUUC-Oru-084554	Oryza rufipogon	39.05	1.00e-66	246.00
IUUC-Osa-085355	Oryza sativa	41.55	7.00e-78	283.00
IUUC-Ola-087209	Oryzias latipes	41.43	5.00e-79	287.00
IUUC-Olu-087699	Ostreococcus lucimarinus	38.77	9.00e-63	231.00
IUUC-Oga-088776	Otolemur garnettii	41.67	2.00e-77	281.00
IUUC-Oar-089441	Ovis aries	42.08	9.00e-79	286.00
IUUC-Ptr-091273	Pan troglodytes	41.67	1.00e-77	282.00
IUUC-Pan-091981	Papio anubis	41.67	2.00e-77	282.00
IUUC-Psi-093251	Pelodiscus sinensis	33.21	2.00e-56	211.00
IUUC-Pma-094738	Petromyzon marinus	39.52	6.00e-73	267.00
IUUC-Pno-095132	Phaeosphaeria nodorum	32.83	5.00e-53	200.00
IUUC-Ppa-095682	Physcomitrella patens	39.48	1.00e-75	276.00
IUUC-Pfo-097511	Poecilia formosa	42.62	2.00e-80	291.00
IUUC-Pab-098570	Pongo abelii	38.62	1.00e-68	252.00
IUUC-Pop-098928	Populus trichocarpa	40.52	1.00e-67	249.00
IUUC-Pca-100987	Procavia capensis	41.85	2.00e-72	265.00
IUUC-Ppe-101281	Prunus persica	38.41	1.00e-75	276.00
IUUC-Pva-102887	Pteropus vampyrus	38.39	6.00e-69	253.00
IUUC-Pgr-103513	Puccinia graminis	38.00	2.00e-77	281.00
IUUC-Ptt-103967	Puccinia triticina	36.63	2.00e-68	251.00
IUUC-Pte-104105	Pyrenophora teres	39.39	2.00e-82	298.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	39.18	1.00e-81	296.00
IUUC-Rno-106028	Rattus norvegicus	34.83	5.00e-50	191.00
IUUC-Sce-106446	Saccharomyces cerevisiae	45.66	3.00e-128	450.00
IUUC-Sha-107108	Sarcophilus harrisii	39.81	4.00e-74	270.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	39.71	2.00e-77	281.00
IUUC-Spo-108097	Schizosaccharomyces pombe	35.93	8.00e-74	270.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	38.84	5.00e-80	290.00
IUUC-Smo-108853	Selaginella moellendorffii	39.81	2.00e-74	272.00
IUUC-Sit-110457	Setaria italica	39.58	3.00e-68	251.00
IUUC-Sly-111362	Solanum lycopersicum	39.81	2.00e-67	248.00
IUUC-Sbi-113882	Sorghum bicolor	39.11	1.00e-66	246.00
IUUC-Sre-115038	Sporisorium reilianum	42.42	1.00e-83	302.00
IUUC-Ssc-116103	Sus scrofa	33.71	3.00e-68	251.00
IUUC-Tgu-116729	Taeniopygia guttata	41.19	3.00e-78	284.00
IUUC-Tru-118068	Takifugu rubripes	41.67	5.00e-80	290.00
IUUC-Tsy-118942	Tarsius syrichta	44.02	7.00e-52	197.00
IUUC-Tni-120732	Tetraodon nigroviridis	40.95	3.00e-75	274.00
IUUC-Tca-121770	Theobroma cacao	40.09	1.00e-79	289.00
IUUC-Tre-121892	Trichoderma reesei	39.60	3.00e-79	288.00
IUUC-Tvi-122354	Trichoderma virens	39.38	1.00e-81	295.00
IUUC-Tae-125580	Triticum aestivum	40.98	3.00e-75	274.00
IUUC-Tur-126086	Triticum urartu	38.30	7.00e-71	260.00
IUUC-Tme-127102	Tuber melanosporum	39.66	5.00e-81	293.00
IUUC-Tbe-127351	Tupaia belangeri	38.96	8.00e-58	216.00
IUUC-Ttr-129061	Tursiops truncatus	41.85	8.00e-73	266.00
IUUC-Uma-129343	Ustilago maydis	42.89	5.00e-87	313.00
IUUC-Vda-129748	Verticillium dahliae	38.24	2.00e-76	278.00
IUUC-Vvi-131524	Vitis vinifera	39.59	2.00e-77	282.00
IUUC-Xtr-132094	Xenopus tropicalis	40.71	4.00e-76	277.00
IUUC-Xma-133923	Xiphophorus maculatus	42.62	2.00e-80	291.00
IUUC-Yli-134496	Yarrowia lipolytica	37.79	8.00e-88	316.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence