iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012377

Ensembl Protein ID

ENSBTAP00000020113.4

UniProt Accession

A3KMV2; RD23A_BOVIN

Genbank Protein ID

AAI33283.1

Protein Name

UV excision repair protein RAD23 homolog A

Genbank Nucleotide ID

BC133282

Gene Name

RAD23A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000015116.5	ENSBTAT00000020113.4	ENSBTAP00000020113.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	7.00e-21	73.8	162	201
ULD/UDP/UBQ/UBQ_PIM	2.90e-26	91.4	3	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLldg 41
           e+e +l ++++MG++re+++ aLra++nn+ +AveyLl+g
   Q: 162  EYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTG 201
           7899**********************************97 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesg...vppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +++t+ktl++++f++++++d+tv+ lKeki++e+g   +p++ qkLIyaGkiL+Dd +++++ i+++++v+++v+k+k
   Q: 3    VTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGrdaFPVAGQKLIYAGKILSDDVPIRDYRIDEKNFVVVMVTKAK 80
           68*************************************************************************987 PP

Organism

Bos taurus

Functional Description
(View)

Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, XPC:RAD23A dimer has NER activity. Can stabilize XPC (By similarity).

Protein Sequence
(Fasta)

MAVTITLKTL QQQTFKIRME PDETVKVLKE KIEAEKGRDA FPVAGQKLIY AGKILSDDVP 60
IRDYRIDEKN FVVVMVTKAK TSPGTSVPSE ASPTATPESS TSFPSAPASG MSHPPPTARE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCATGTCGT GTGAGGATTC CGGGGCCGCT GTGTCGCTCG GGTCCCACCA TGGCCGTCAC 60
GATCACGCTC AAAACACTGC AGCAGCAGAC CTTCAAGATC CGCATGGAGC CTGATGAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0832--Ubl conjugation

Interpro

IPR004806--Rad23
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR015360--XPC-bd

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin
PF09280--XPC-binding

PRINTS

PR01839--RAD23PROTEIN

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005654--C:nucleoplasm
GO:0000502--C:proteasome complex
GO:0003684--F:damaged DNA binding
GO:0006289--P:nucleotide-excision repair
GO:0045070--P:positive regulation of viral genome replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process

KEGG

bta:540564

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001515	Ailuropoda melanoleuca	93.31	2.00e-146	511.00
IUUC-Aca-004704	Anolis carolinensis	79.20	7.00e-111	393.00
IUUC-Ago-007830	Ashbya gossypii	28.57	3.00e-16	79.70
IUUC-Acl-008212	Aspergillus clavatus	35.80	6.00e-25	108.00
IUUC-Afl-008605	Aspergillus flavus	34.88	1.00e-24	107.00
IUUC-Ani-009460	Aspergillus nidulans	38.40	3.00e-29	122.00
IUUC-Aor-010032	Aspergillus oryzae	34.88	3.00e-24	106.00
IUUC-Ame-011107	Astyanax mexicanus	69.31	5.00e-33	135.00
IUUC-Bgr-012056	Blumeria graminis	33.96	1.00e-21	97.40
IUUC-Bra-016970	Brassica rapa	33.94	2.00e-49	189.00
IUUC-Cel-018364	Caenorhabditis elegans	31.61	1.00e-26	114.00
IUUC-Cja-018946	Callithrix jacchus	94.77	2.00e-142	498.00
IUUC-Cfa-020577	Canis familiaris	97.79	8.00e-160	556.00
IUUC-Cpo-021850	Cavia porcellus	90.88	5.00e-164	570.00
IUUC-Csa-023183	Chlorocebus sabaeus	95.87	3.00e-151	527.00
IUUC-Cgl-026495	Colletotrichum gloeosporioides	32.51	6.00e-22	98.20
IUUC-Cme-027260	Cyanidioschyzon merolae	27.51	4.00e-25	108.00
IUUC-Dno-030017	Dasypus novemcinctus	90.93	6.00e-131	460.00
IUUC-Dor-030358	Dipodomys ordii	82.42	1.00e-123	436.00
IUUC-Dme-032027	Drosophila melanogaster	41.53	4.00e-65	241.00
IUUC-Eca-033599	Equus caballus	93.22	2.00e-136	478.00
IUUC-Fca-036051	Felis catus	96.96	2.00e-157	548.00
IUUC-Fso-038107	Fusarium solani	36.11	5.00e-24	105.00
IUUC-Gga-040133	Gallus gallus	87.38	2.00e-75	275.00
IUUC-Gac-042298	Gasterosteus aculeatus	59.77	9.00e-86	310.00
IUUC-Ggo-045084	Gorilla gorilla	96.14	2.00e-151	528.00
IUUC-Hsa-046614	Homo sapiens	96.14	5.00e-152	530.00
IUUC-Itr-047875	Ictidomys tridecemlineatus	95.59	4.00e-170	590.00
IUUC-Lch-050563	Latimeria chalumnae	62.16	5.00e-106	377.00
IUUC-Lpe-051168	Leersia perrieri	39.57	1.00e-35	143.00
IUUC-Loc-051758	Lepisosteus oculatus	63.24	3.00e-87	315.00
IUUC-Laf-054589	Loxodonta africana	95.59	5.00e-146	510.00
IUUC-Mcc-055860	Macaca mulatta	95.87	3.00e-151	527.00
IUUC-Meu-056459	Macropus eugenii	93.02	7.00e-103	367.00
IUUC-Mtr-058239	Medicago truncatula	32.35	3.00e-47	182.00
IUUC-Mmr-060819	Microcebus murinus	96.13	7.00e-166	576.00
IUUC-Mdo-062742	Monodelphis domestica	84.38	3.00e-143	501.00
IUUC-Mmu-063929	Mus musculus	92.84	7.00e-159	553.00
IUUC-Mac-064724	Musa acuminata	34.05	5.00e-47	181.00
IUUC-Mpu-066684	Mustela putorius furo	97.52	2.00e-159	554.00
IUUC-Mlu-067787	Myotis lucifugus	95.59	8.00e-153	533.00
IUUC-Nle-069846	Nomascus leucogenys	84.97	2.00e-132	465.00
IUUC-Ont-072271	Oreochromis niloticus	55.95	2.00e-88	319.00
IUUC-Oan-073572	Ornithorhynchus anatinus	79.83	5.00e-131	460.00
IUUC-Ocu-074968	Oryctolagus cuniculus	93.60	5.00e-105	375.00
IUUC-Obr-076909	Oryza brachyantha	34.43	5.00e-44	171.00
IUUC-Oga-089075	Otolemur garnettii	95.03	1.00e-147	515.00
IUUC-Oar-090387	Ovis aries	98.62	6.00e-149	520.00
IUUC-Ptr-090912	Pan troglodytes	92.56	3.00e-141	494.00
IUUC-Pan-092140	Papio anubis	95.87	1.00e-150	525.00
IUUC-Psi-093347	Pelodiscus sinensis	86.39	4.00e-62	231.00
IUUC-Pno-095064	Phaeosphaeria nodorum	35.82	2.00e-17	83.60
IUUC-Pfo-096607	Poecilia formosa	64.57	1.00e-96	346.00
IUUC-Pab-097738	Pongo abelii	92.29	1.00e-143	502.00
IUUC-Pop-099642	Populus trichocarpa	35.24	4.00e-50	191.00
IUUC-Pca-100348	Procavia capensis	92.86	4.00e-142	497.00
IUUC-Ppe-101522	Prunus persica	34.40	1.00e-50	193.00
IUUC-Pva-102412	Pteropus vampyrus	96.97	2.00e-157	548.00
IUUC-Pgr-103618	Puccinia graminis	36.29	2.00e-24	106.00
IUUC-Rno-105569	Rattus norvegicus	93.09	6.00e-150	523.00
IUUC-Sha-106918	Sarcophilus harrisii	83.92	2.00e-130	458.00
IUUC-Sja-107851	Schizosaccharomyces japonicus	35.04	2.00e-44	172.00
IUUC-Smo-109129	Selaginella moellendorffii	38.40	5.00e-33	135.00
IUUC-Sit-109813	Setaria italica	36.20	6.00e-48	184.00
IUUC-Stu-112027	Solanum tuberosum	36.68	5.00e-54	204.00
IUUC-Sbi-114459	Sorghum bicolor	33.94	6.00e-47	181.00
IUUC-Ssc-115460	Sus scrofa	96.97	8.00e-156	543.00
IUUC-Tru-118651	Takifugu rubripes	49.88	1.00e-82	299.00
IUUC-Tsy-119385	Tarsius syrichta	79.04	2.00e-69	254.00
IUUC-Tni-120493	Tetraodon nigroviridis	59.89	5.00e-93	334.00
IUUC-Tca-121594	Theobroma cacao	36.80	2.00e-51	196.00
IUUC-Tre-121911	Trichoderma reesei	31.33	2.00e-28	119.00
IUUC-Tme-127092	Tuber melanosporum	38.12	1.00e-26	113.00
IUUC-Tbe-127603	Tupaia belangeri	83.94	1.00e-54	206.00
IUUC-Ttr-129232	Tursiops truncatus	86.50	6.00e-145	506.00
IUUC-Vda-129946	Verticillium dahliae	32.86	1.00e-20	94.40

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence