iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012563

Ensembl Protein ID

ENSBTAP00000001976.5

UniProt Accession

G5E517; G5E517_BOVIN

Genbank Protein ID

ENSBTAP00000001976

Protein Name

E3 ubiquitin-protein ligase SH3RF1

Genbank Nucleotide ID

DAAA02021747

Gene Name

SH3RF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000001508.5	ENSBTAT00000001976.5	ENSBTAP00000001976.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.30e-48	160.2	313	367

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
             ++y+y++ ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+v+ +
   Q: 313  YVAIYPYTPRKEDELELRKGEMFLVF-ERC-QDGWFKGTSMHTSKIGVFPGNYVAPV 367
           579**********************9.555.569********************988 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

GIPQLPCAKA LYNYEGKEPG DLKFSKGDII VLRRQVDENW YHGEVGGVHG FFPTNFVQII 60
KPLPQPPPQC KALYDFEVKD KEADKDCLPF AKDDVLTVIR RVDENWAEGM LADKIGIFPI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAATACCTC AGTTACCATG TGCCAAAGCA TTATACAACT ACGAAGGCAA GGAGCCCGGG 60
GACCTTAAGT TCAGCAAAGG CGACATCATT GTCCTGCGGC GACAGGTGGA TGAGAACTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028502--SH3RF1

PROSITE

PS50002--SH3

Pfam

PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	72.57	0.00e+00	850.00
IUUC-Apl-003961	Anas platyrhynchos	69.49	0.00e+00	828.00
IUUC-Aca-004386	Anolis carolinensis	65.69	0.00e+00	820.00
IUUC-Ame-010659	Astyanax mexicanus	61.16	2.00e-156	546.00
IUUC-Cja-019730	Callithrix jacchus	71.30	0.00e+00	853.00
IUUC-Cfa-020992	Canis familiaris	74.43	0.00e+00	878.00
IUUC-Cpo-021304	Cavia porcellus	72.16	0.00e+00	893.00
IUUC-Csa-023925	Chlorocebus sabaeus	72.54	0.00e+00	850.00
IUUC-Cho-024630	Choloepus hoffmanni	67.08	0.00e+00	684.00
IUUC-Dre-028290	Danio rerio	62.62	6.00e-163	568.00
IUUC-Dno-029083	Dasypus novemcinctus	81.76	0.00e+00	676.00
IUUC-Dor-030388	Dipodomys ordii	88.00	3.00e-111	396.00
IUUC-Ete-032809	Echinops telfairi	68.64	0.00e+00	694.00
IUUC-Eca-034185	Equus caballus	73.77	0.00e+00	881.00
IUUC-Eeu-034816	Erinaceus europaeus	61.08	1.00e-147	516.00
IUUC-Fca-036439	Felis catus	72.27	0.00e+00	894.00
IUUC-Fal-037074	Ficedula albicollis	68.90	0.00e+00	811.00
IUUC-Gmo-039443	Gadus morhua	60.21	8.00e-121	427.00
IUUC-Gga-040749	Gallus gallus	75.63	0.00e+00	663.00
IUUC-Gac-041420	Gasterosteus aculeatus	76.82	5.00e-103	369.00
IUUC-Ggo-045215	Gorilla gorilla	72.62	0.00e+00	855.00
IUUC-Hsa-046315	Homo sapiens	72.52	0.00e+00	855.00
IUUC-Lch-049453	Latimeria chalumnae	64.85	0.00e+00	796.00
IUUC-Loc-052248	Lepisosteus oculatus	38.37	2.00e-74	273.00
IUUC-Laf-053651	Loxodonta africana	70.57	0.00e+00	855.00
IUUC-Mcc-054688	Macaca mulatta	72.60	0.00e+00	865.00
IUUC-Meu-056291	Macropus eugenii	63.84	7.00e-172	597.00
IUUC-Mga-059944	Meleagris gallopavo	68.86	0.00e+00	677.00
IUUC-Mmr-061553	Microcebus murinus	71.88	0.00e+00	844.00
IUUC-Mdo-062313	Monodelphis domestica	65.60	0.00e+00	751.00
IUUC-Mmu-063516	Mus musculus	73.46	0.00e+00	904.00
IUUC-Mpu-066064	Mustela putorius furo	74.10	0.00e+00	850.00
IUUC-Mlu-067312	Myotis lucifugus	81.28	0.00e+00	680.00
IUUC-Nle-069035	Nomascus leucogenys	72.22	0.00e+00	854.00
IUUC-Opr-070690	Ochotona princeps	64.49	3.00e-127	449.00
IUUC-Ont-071484	Oreochromis niloticus	60.04	1.00e-155	543.00
IUUC-Oan-073305	Ornithorhynchus anatinus	79.71	0.00e+00	697.00
IUUC-Ocu-074936	Oryctolagus cuniculus	80.98	0.00e+00	711.00
IUUC-Ola-086675	Oryzias latipes	59.83	5.00e-127	448.00
IUUC-Oga-087933	Otolemur garnettii	71.60	0.00e+00	833.00
IUUC-Oar-090408	Ovis aries	91.97	0.00e+00	915.00
IUUC-Ptr-090865	Pan troglodytes	72.52	0.00e+00	857.00
IUUC-Pan-092362	Papio anubis	72.67	0.00e+00	852.00
IUUC-Psi-093876	Pelodiscus sinensis	68.44	0.00e+00	681.00
IUUC-Pfo-097116	Poecilia formosa	61.97	7.00e-160	557.00
IUUC-Pab-098127	Pongo abelii	72.26	0.00e+00	855.00
IUUC-Pca-100485	Procavia capensis	78.11	0.00e+00	674.00
IUUC-Pva-102661	Pteropus vampyrus	71.66	0.00e+00	842.00
IUUC-Rno-105728	Rattus norvegicus	72.12	0.00e+00	864.00
IUUC-Sha-106515	Sarcophilus harrisii	74.02	2.00e-166	578.00
IUUC-Sar-113161	Sorex araneus	88.00	8.00e-108	384.00
IUUC-Ssc-115314	Sus scrofa	82.32	0.00e+00	884.00
IUUC-Tgu-117012	Taeniopygia guttata	70.52	0.00e+00	692.00
IUUC-Tru-118467	Takifugu rubripes	61.32	5.00e-158	551.00
IUUC-Tsy-119566	Tarsius syrichta	85.99	1.00e-118	421.00
IUUC-Tni-120830	Tetraodon nigroviridis	51.81	9.00e-117	414.00
IUUC-Tbe-128070	Tupaia belangeri	88.89	8.00e-120	424.00
IUUC-Ttr-128161	Tursiops truncatus	75.10	4.00e-142	498.00
IUUC-Xtr-132628	Xenopus tropicalis	74.69	0.00e+00	644.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence