iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091415

Ensembl Protein ID

ENSPTRP00000038793.3

UniProt Accession

H2QZC9; H2QZC9_PANTR

Genbank Protein ID

ENSPTRP00000038793

Protein Name

Lysine-specific demethylase 5D

Genbank Nucleotide ID

AC144429

Gene Name

KDM5D

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000022503.5	ENSPTRT00000042025.3	ENSPTRP00000038793.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.70e-14	52.0	316	362

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +g+ed+ +l+ C+ C++++H  Cl ++  +e p+   w CpkC 
   Q: 316  ICQVCSRGDEDD-KLLFCDGCDDNYHIFCLLPP-LPEIPRGI-WRCPKCI 362
           7*********88.6*******************.******97.******5 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MEPGCNEFLP PPECPVFEPS WAEFQDPLGY IAKIRPIAEK SGICKIRPPA DWQPPFAVEV 60
DNFRFTPRIQ RLNELEAQTR VKLNYLDQIA KFWEIQGSSL KIPNVERKIL DLYSLSKIVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATTTTAAAA AAAGATCCGG CCATACTATT TTTATCTTGC TTTTTCGTTC TGTCGCAGTA 60
CTGTTTAATA TGAGTCCAGC GACGGCTCTG TGACTATTTT CCTCTGGTAA AATCGCTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0032453--F:histone demethylase activity (H3-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0008270--F:zinc ion binding
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0002457--P:T cell antigen processing and presentation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001327	Ailuropoda melanoleuca	84.41	0.00e+00	2317.00
IUUC-Aca-004712	Anolis carolinensis	74.43	0.00e+00	1854.00
IUUC-Bta-013099	Bos taurus	88.18	0.00e+00	2337.00
IUUC-Cja-018723	Callithrix jacchus	80.82	0.00e+00	2234.00
IUUC-Cfa-020954	Canis familiaris	86.81	0.00e+00	2311.00
IUUC-Csa-023682	Chlorocebus sabaeus	94.41	0.00e+00	2679.00
IUUC-Dre-028238	Danio rerio	60.34	0.00e+00	1768.00
IUUC-Dno-029435	Dasypus novemcinctus	87.08	0.00e+00	2306.00
IUUC-Dor-030226	Dipodomys ordii	80.53	0.00e+00	1587.00
IUUC-Eca-033834	Equus caballus	87.98	0.00e+00	2353.00
IUUC-Eeu-034692	Erinaceus europaeus	84.15	0.00e+00	1790.00
IUUC-Fca-035766	Felis catus	84.21	0.00e+00	2212.00
IUUC-Gmo-039140	Gadus morhua	61.64	0.00e+00	1704.00
IUUC-Gac-041825	Gasterosteus aculeatus	61.78	0.00e+00	1717.00
IUUC-Ggo-045492	Gorilla gorilla	84.73	0.00e+00	2380.00
IUUC-Hsa-046399	Homo sapiens	97.01	0.00e+00	2745.00
IUUC-Itr-048348	Ictidomys tridecemlineatus	84.71	0.00e+00	2355.00
IUUC-Lch-050517	Latimeria chalumnae	71.73	0.00e+00	1996.00
IUUC-Laf-054098	Loxodonta africana	87.77	0.00e+00	1461.00
IUUC-Mcc-055474	Macaca mulatta	93.43	0.00e+00	2720.00
IUUC-Meu-056643	Macropus eugenii	79.34	0.00e+00	2110.00
IUUC-Mmr-061032	Microcebus murinus	87.71	0.00e+00	2355.00
IUUC-Mdo-062754	Monodelphis domestica	74.40	0.00e+00	2026.00
IUUC-Mmu-063943	Mus musculus	82.96	0.00e+00	2323.00
IUUC-Mpu-066800	Mustela putorius furo	84.89	0.00e+00	2326.00
IUUC-Mlu-067109	Myotis lucifugus	84.54	0.00e+00	2312.00
IUUC-Nle-069569	Nomascus leucogenys	88.03	0.00e+00	2308.00
IUUC-Ont-072274	Oreochromis niloticus	63.53	0.00e+00	1761.00
IUUC-Oan-073160	Ornithorhynchus anatinus	80.43	0.00e+00	2107.00
IUUC-Ocu-074440	Oryctolagus cuniculus	84.54	0.00e+00	2311.00
IUUC-Ola-087059	Oryzias latipes	67.41	0.00e+00	1793.00
IUUC-Oga-088191	Otolemur garnettii	84.77	0.00e+00	2350.00
IUUC-Oar-090027	Ovis aries	88.18	0.00e+00	2338.00
IUUC-Pan-091829	Papio anubis	84.57	0.00e+00	2364.00
IUUC-Pma-094137	Petromyzon marinus	51.78	0.00e+00	1342.00
IUUC-Pfo-096645	Poecilia formosa	63.41	0.00e+00	1727.00
IUUC-Pab-097582	Pongo abelii	86.68	0.00e+00	2159.00
IUUC-Pca-100446	Procavia capensis	83.74	0.00e+00	2272.00
IUUC-Pva-102553	Pteropus vampyrus	83.90	0.00e+00	1452.00
IUUC-Rno-105359	Rattus norvegicus	79.82	0.00e+00	2352.00
IUUC-Sha-106769	Sarcophilus harrisii	82.28	0.00e+00	1974.00
IUUC-Ssc-116354	Sus scrofa	84.55	0.00e+00	2377.00
IUUC-Tru-117667	Takifugu rubripes	63.66	0.00e+00	1618.00
IUUC-Tni-119920	Tetraodon nigroviridis	62.77	0.00e+00	1709.00
IUUC-Tbe-128040	Tupaia belangeri	91.32	0.00e+00	1008.00
IUUC-Ttr-128979	Tursiops truncatus	87.71	0.00e+00	2353.00
IUUC-Vpa-130433	Vicugna pacos	87.83	0.00e+00	1589.00
IUUC-Xtr-132324	Xenopus tropicalis	66.71	0.00e+00	1830.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence