iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037119

Ensembl Protein ID

ENSFALP00000008443.1

UniProt Accession

U3K089; U3K089_FICAL

Genbank Protein ID

ENSFALP00000008443

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01011544

Gene Name

KLHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000008105.1	ENSFALT00000008481.1	ENSFALP00000008443.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.20e-21	76.5	18	84
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.00e-09	37.5	117	148

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv++v + +e +ah++vLaa+S++F a+f+++++esk  +++eikdv+ + +r l++++Yt +++ +
   Q: 18   CDVVIVAETVEMEAHRVVLAACSPYFCAMFTGDMSESK-AKKIEIKDVDGQTLRKLIDYIYTAEIEVT 84
           8*************************************.************************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclgi++fAd + c +L ++a+ ++++hF+
   Q: 117  PTNCLGIRAFADVHACAELLQQANAYAEQHFP 148
           78*****************************6 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MRKAFKVMNE LRSKRLLCDV VIVAETVEME AHRVVLAACS PYFCAMFTGD MSESKAKKIE 60
IKDVDGQTLR KLIDYIYTAE IEVTEENVQV LLPAASLLQL MDVRKNCCDF LQSQLHPTNC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTTAAGCAG AGCTCGCGTT CCTCTGAGGC AGCTGAAGAT GAAAAGGACC AGCGTACAGT 60
GACAGTCAAT CCCTCTCACA TGAGAAAGGC TTTCAAGGTC ATGAATGAAT TACGGAGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0072156--P:distal tubule morphogenesis
GO:0050801--P:ion homeostasis
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0070294--P:renal sodium ion absorption

KEGG

fab:101819966

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001632	Ailuropoda melanoleuca	96.23	0.00e+00	1092.00
IUUC-Apl-003965	Anas platyrhynchos	99.28	0.00e+00	1101.00
IUUC-Aca-004912	Anolis carolinensis	96.22	0.00e+00	1068.00
IUUC-Ame-010670	Astyanax mexicanus	82.16	0.00e+00	933.00
IUUC-Bta-013354	Bos taurus	96.23	0.00e+00	1093.00
IUUC-Bol-016582	Brassica oleracea	30.28	4.00e-13	70.10
IUUC-Bra-017771	Brassica rapa	30.73	1.00e-13	71.60
IUUC-Cel-018136	Caenorhabditis elegans	43.08	3.00e-129	455.00
IUUC-Cja-019183	Callithrix jacchus	90.83	0.00e+00	994.00
IUUC-Cfa-020465	Canis familiaris	95.13	0.00e+00	1078.00
IUUC-Cpo-022115	Cavia porcellus	96.04	0.00e+00	1092.00
IUUC-Csa-024219	Chlorocebus sabaeus	96.22	0.00e+00	1095.00
IUUC-Csv-026032	Ciona savignyi	60.77	0.00e+00	706.00
IUUC-Cgl-026620	Colletotrichum gloeosporioides	30.10	8.00e-24	103.00
IUUC-Dre-028524	Danio rerio	76.38	0.00e+00	935.00
IUUC-Dno-029075	Dasypus novemcinctus	96.58	0.00e+00	1098.00
IUUC-Dor-030156	Dipodomys ordii	79.64	0.00e+00	881.00
IUUC-Ete-033064	Echinops telfairi	80.92	0.00e+00	785.00
IUUC-Eca-033887	Equus caballus	95.50	0.00e+00	1085.00
IUUC-Eeu-035244	Erinaceus europaeus	75.68	0.00e+00	844.00
IUUC-Fca-035375	Felis catus	95.87	0.00e+00	1089.00
IUUC-Gga-041094	Gallus gallus	99.10	0.00e+00	1097.00
IUUC-Gac-042585	Gasterosteus aculeatus	79.21	0.00e+00	907.00
IUUC-Ggo-045485	Gorilla gorilla	95.70	0.00e+00	1085.00
IUUC-Hsa-046717	Homo sapiens	96.22	0.00e+00	1094.00
IUUC-Itr-048605	Ictidomys tridecemlineatus	96.40	0.00e+00	1095.00
IUUC-Kpa-049336	Komagataella pastoris	43.48	1.30e+00	27.30
IUUC-Lch-050246	Latimeria chalumnae	88.87	0.00e+00	983.00
IUUC-Laf-053700	Loxodonta africana	95.99	0.00e+00	1074.00
IUUC-Mcc-054732	Macaca mulatta	96.83	0.00e+00	1000.00
IUUC-Mga-059994	Meleagris gallopavo	99.40	0.00e+00	986.00
IUUC-Mdo-062923	Monodelphis domestica	96.58	0.00e+00	1098.00
IUUC-Mmu-063842	Mus musculus	96.22	0.00e+00	1090.00
IUUC-Mpu-066380	Mustela putorius furo	96.22	0.00e+00	1095.00
IUUC-Mlu-067922	Myotis lucifugus	96.17	0.00e+00	1078.00
IUUC-Nle-069761	Nomascus leucogenys	96.22	0.00e+00	1094.00
IUUC-Opr-070287	Ochotona princeps	87.75	0.00e+00	976.00
IUUC-Ont-071654	Oreochromis niloticus	81.44	0.00e+00	946.00
IUUC-Ocu-074957	Oryctolagus cuniculus	95.33	0.00e+00	1076.00
IUUC-Ola-086853	Oryzias latipes	80.72	0.00e+00	903.00
IUUC-Oga-088559	Otolemur garnettii	95.69	0.00e+00	1087.00
IUUC-Oar-089925	Ovis aries	96.23	0.00e+00	1094.00
IUUC-Ptr-091487	Pan troglodytes	96.22	0.00e+00	1094.00
IUUC-Pan-091705	Papio anubis	96.22	0.00e+00	1095.00
IUUC-Psi-093478	Pelodiscus sinensis	93.45	0.00e+00	1019.00
IUUC-Pfo-097450	Poecilia formosa	81.80	0.00e+00	889.00
IUUC-Pab-097618	Pongo abelii	96.04	0.00e+00	1091.00
IUUC-Pca-100739	Procavia capensis	87.47	0.00e+00	648.00
IUUC-Sha-106935	Sarcophilus harrisii	97.60	0.00e+00	746.00
IUUC-Ssc-115599	Sus scrofa	96.58	0.00e+00	1096.00
IUUC-Tgu-117001	Taeniopygia guttata	99.27	0.00e+00	1085.00
IUUC-Tru-118078	Takifugu rubripes	80.00	0.00e+00	934.00
IUUC-Tsy-119161	Tarsius syrichta	84.14	0.00e+00	833.00
IUUC-Tni-120888	Tetraodon nigroviridis	77.70	0.00e+00	877.00
IUUC-Tbe-127285	Tupaia belangeri	81.28	1.00e-177	615.00
IUUC-Ttr-128574	Tursiops truncatus	69.91	0.00e+00	775.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence