iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020247

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03016752

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000009800.3	ENSCAFT00000015560.3	ENSCAFP00000014398.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.10e-88	298.2	704	1025

Active Site

Position(s)	Description	Evidence
995	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrll 88
           ++dl+++l+v+f+gE g+d gGv+ ef+++l++e+ +p++g+f+y e+ +++++p   ++    e+ ++F f+G+l+g++l++ ++ 
   Q: 704  NEDLRRELMVSFSGEIGHDSGGVKVEFFHCLFEEMTRPEYGMFTYPEDASYMWFPVTPKF----EKKRYF-FFGVLCGLSLFNFNVA 785
           6899*****************************************************999....567888.99************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
           ++p++ +++k+ll++  sledl+e+ p l ksl+ +++ + +d  e  + + f    ++  + ++++L+p+G+ i V ++Nk++Yv+
   Q: 786  NIPFPLALFKKLLDQTPSLEDLKELSPVLGKSLQTLLDDEGDDFGEV-FLIYF----NVHWDKNDVDLIPNGSGIIVDQTNKRDYVS 867
           *************************************8855555554.55555....5666889999******************** PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           ++v+y+++ ++k  +e+f++Gf++v+++++++ F++eel+ ++ G++++d+e+++k++ y++gy +++p+i +Fw++l++++ ee+k
   Q: 868  KYVNYIFNISVKAVYEEFQRGFYKVCDKDIIEFFHPEELKDVVIGNTDYDWETFEKNAHYEEGYDNSHPTIVMFWKALHKLTLEEKK 954
           *************************************************************************************** PP
   S: 263  afLqFvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           +fL F+Tg++r+ ++G++++k   f+++++ ++++ ++++TC+++L LP+Ys++e ++e L++Ai++++gF+
   Q: 955  KFLVFLTGTDRIQVKGLKNMK-ITFCCPENVNEKDPIRAQTCISVLYLPKYSTMERVEEALQVAINNSRGFG 1025
           *********************.77999999****************************************96 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MERRPPRRAR GGARPAPGPR PAPRRPAEPP GTQLWLFPSA AGLRRALPPR AEATIDVICS 60
LLHQAFLCRR LTDFVLQSSP RSKPKKCIKL GKKMKIHSVD QGAEHMLILS SDGKPFEYNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCGCA GGCCCCCCAG GAGAGCTCGG GGCGGCGCGC GCCCGGCGCC CGGGCCGCGC 60
CCCGCGCCCC GACGCCCCGC GGAGCCGCCG GGCACCCAGC TCTGGCTCTT CCCCAGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001676	Ailuropoda melanoleuca	90.85	0.00e+00	1883.00
IUUC-Cja-018751	Callithrix jacchus	75.70	0.00e+00	1512.00
IUUC-Csa-023204	Chlorocebus sabaeus	78.00	0.00e+00	1401.00
IUUC-Cho-025101	Choloepus hoffmanni	66.40	0.00e+00	674.00
IUUC-Dno-029795	Dasypus novemcinctus	72.83	0.00e+00	1169.00
IUUC-Dor-030862	Dipodomys ordii	67.40	0.00e+00	1287.00
IUUC-Ete-032585	Echinops telfairi	61.50	0.00e+00	858.00
IUUC-Eca-034358	Equus caballus	83.19	0.00e+00	1613.00
IUUC-Eeu-035282	Erinaceus europaeus	72.87	0.00e+00	835.00
IUUC-Fca-036505	Felis catus	91.59	0.00e+00	1807.00
IUUC-Ggo-045445	Gorilla gorilla	74.10	0.00e+00	1402.00
IUUC-Hsa-046342	Homo sapiens	76.60	0.00e+00	1481.00
IUUC-Itr-049004	Ictidomys tridecemlineatus	73.20	0.00e+00	1459.00
IUUC-Laf-053921	Loxodonta africana	74.53	0.00e+00	1502.00
IUUC-Mcc-054850	Macaca mulatta	78.00	0.00e+00	1405.00
IUUC-Mmr-060783	Microcebus murinus	67.91	0.00e+00	1227.00
IUUC-Mpu-066123	Mustela putorius furo	89.69	0.00e+00	1831.00
IUUC-Mlu-067914	Myotis lucifugus	82.87	0.00e+00	1545.00
IUUC-Nle-069986	Nomascus leucogenys	76.13	0.00e+00	1503.00
IUUC-Opr-070513	Ochotona princeps	70.22	0.00e+00	1038.00
IUUC-Ocu-074305	Oryctolagus cuniculus	74.63	0.00e+00	1448.00
IUUC-Oar-089456	Ovis aries	82.98	0.00e+00	1627.00
IUUC-Ptr-091216	Pan troglodytes	71.08	0.00e+00	1364.00
IUUC-Pan-091706	Papio anubis	75.85	0.00e+00	1448.00
IUUC-Pca-100320	Procavia capensis	68.53	0.00e+00	1362.00
IUUC-Pva-102646	Pteropus vampyrus	86.59	0.00e+00	1736.00
IUUC-Sar-113605	Sorex araneus	79.76	3.00e-158	552.00
IUUC-Ssc-116076	Sus scrofa	83.75	0.00e+00	647.00
IUUC-Tsy-119240	Tarsius syrichta	65.03	0.00e+00	1225.00
IUUC-Tbe-127787	Tupaia belangeri	73.99	0.00e+00	1405.00
IUUC-Ttr-128191	Tursiops truncatus	80.60	0.00e+00	1587.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence