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Tag Content
UUCD2 ID IUUC-Pab-098249
UUCD1 version UUC-PoA-00628
Ensembl Protein ID ENSPPYP00000024689.1
UniProt Accession H2PDW2; H2PDW2_PONAB
Genbank Protein ID ENSPPYP00000016667
Protein Name Uncharacterized protein
Genbank Nucleotide ID ABGA01271104
Gene Name HERC3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000014927.2 ENSPPYT00000033953.1 ENSPPYP00000024689.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.10e-94 317.7 726 1049
Active Site
Position(s) Description Evidence
1018 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           dlkk l+v f gEe++d+gGvt+ef+ ll+kel np +g+f+y ++++  ++ +         + ++F+++G+ +g+a++++ ++dl
   Q: 726  DLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFV-----EHNWFHLIGITCGLAIYNSTVVDL 807
           899******************************************9999999776554.....579********************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklv 177
           +++ ++yk+ll++k  ledl+e+ p+  +sl+e++++  +d+ee+ ++l+f++  e++g +++++L+pgG+n+ V  +N++e+v+++
   Q: 808  HFPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEET-FCLNFTICRESYGVIEQKKLIPGGDNVTVCRDNRQEFVDAY 893
           *************************************99999997.******99********************************* PP
   S: 178  veyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
           v+y ++ +++e ++af++Gf +v+  ++l+lF+++el+ ++ G++++++e+l++++ ykg+y++++p+++ Fwe+++ef  e++k+f
   Q: 894  VNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKF 980
           *************************************************************************************** PP
   S: 265  LqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           L F+Tgs+r+P+ G+a+l+   +vi+  ++ ++ lP ++TC+n+L+LP+Ysskeil  +L+ A ++ +gF+l
   Q: 981  LLFLTGSDRIPIYGMASLQ---IVIQStASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFSL 1049
           *******************...8888867788**************************************97 PP
   
Organism Pongo abelii
Protein Sequence
(Fasta)
MLCWGYWSLG QPGISTNLQG IVAEPQVCGF ISDRSVKEVA CGGNHSVFLL EDGEVYTCGL 60
NTKGQLGHER EGNKPEQIGA LADQHIIHVA CGESHSLALS DRGQLFSWGA GSDGQLGLMT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-098249|E3,HECT|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGAAACTTC CTTATTATTG TGACGCCGAA AACGGAGAAA CCCCGGGTCC GGCGAGAGGG 60
GCTGTGACAG TCGGAGTCCC AAGCTGCGGT TCGGCTGCTG CCGAGGTGCG CAGGGCGGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-098249|E3,HECT|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3
Pfam

PF00632--HECT
PF00415--RCC1
PRINTS

PR00633--RCCNDNSATION
SMART

SM00119--HECTc
Gene Ontology

GO:0005829--C:cytosol
GO:0004842--F:ubiquitin-protein transferase activity
KEGG pon:100434637
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001673 Ailuropoda melanoleuca 98.67 0.00e+00 2094.00
IUUC-Apl-003535 Anas platyrhynchos 88.00 0.00e+00 1878.00
IUUC-Aca-005223 Anolis carolinensis 85.24 0.00e+00 1826.00
IUUC-Ame-010816 Astyanax mexicanus 66.03 0.00e+00 1164.00
IUUC-Bta-013373 Bos taurus 97.62 0.00e+00 2080.00
IUUC-Cel-018150 Caenorhabditis elegans 33.21 2.00e-154 540.00
IUUC-Cja-019609 Callithrix jacchus 99.05 0.00e+00 2096.00
IUUC-Cfa-021071 Canis familiaris 98.48 0.00e+00 2089.00
IUUC-Cpo-021548 Cavia porcellus 97.62 0.00e+00 2072.00
IUUC-Csa-023987 Chlorocebus sabaeus 99.52 0.00e+00 2105.00
IUUC-Cho-024325 Choloepus hoffmanni 98.25 0.00e+00 1205.00
IUUC-Dre-027472 Danio rerio 66.35 0.00e+00 1399.00
IUUC-Dno-029241 Dasypus novemcinctus 97.15 0.00e+00 2061.00
IUUC-Dor-030672 Dipodomys ordii 92.37 0.00e+00 1132.00
IUUC-Ete-032642 Echinops telfairi 92.00 0.00e+00 1895.00
IUUC-Eca-033646 Equus caballus 98.29 0.00e+00 2084.00
IUUC-Eeu-035098 Erinaceus europaeus 84.77 0.00e+00 1376.00
IUUC-Fal-036952 Ficedula albicollis 87.71 0.00e+00 1870.00
IUUC-Gmo-039297 Gadus morhua 64.10 0.00e+00 1317.00
IUUC-Gga-040591 Gallus gallus 86.96 0.00e+00 1854.00
IUUC-Gac-041741 Gasterosteus aculeatus 65.09 0.00e+00 1380.00
IUUC-Gma-043616 Glycine max 38.11 1.00e-52 200.00
IUUC-Ggo-044769 Gorilla gorilla 99.62 0.00e+00 2106.00
IUUC-Hsa-046066 Homo sapiens 99.71 0.00e+00 2110.00
IUUC-Itr-048311 Ictidomys tridecemlineatus 98.48 0.00e+00 2081.00
IUUC-Lch-050301 Latimeria chalumnae 73.24 0.00e+00 1613.00
IUUC-Loc-052803 Lepisosteus oculatus 67.35 0.00e+00 1459.00
IUUC-Laf-053364 Loxodonta africana 98.48 0.00e+00 2087.00
IUUC-Mcc-054930 Macaca mulatta 99.43 0.00e+00 2105.00
IUUC-Meu-056274 Macropus eugenii 79.08 0.00e+00 872.00
IUUC-Mga-059563 Meleagris gallopavo 87.43 0.00e+00 1869.00
IUUC-Mmr-060792 Microcebus murinus 96.29 0.00e+00 2028.00
IUUC-Mdo-062195 Monodelphis domestica 91.53 0.00e+00 1957.00
IUUC-Mmu-063855 Mus musculus 95.05 0.00e+00 2037.00
IUUC-Mpu-066308 Mustela putorius furo 98.76 0.00e+00 2096.00
IUUC-Mlu-066927 Myotis lucifugus 97.62 0.00e+00 2069.00
IUUC-Nle-070090 Nomascus leucogenys 99.52 0.00e+00 2105.00
IUUC-Opr-070891 Ochotona princeps 85.90 0.00e+00 1769.00
IUUC-Ont-072201 Oreochromis niloticus 63.89 0.00e+00 1338.00
IUUC-Ocu-074770 Oryctolagus cuniculus 97.81 0.00e+00 2081.00
IUUC-Ola-086550 Oryzias latipes 65.15 0.00e+00 1389.00
IUUC-Olu-087836 Ostreococcus lucimarinus 35.05 2.00e-43 169.00
IUUC-Oga-088831 Otolemur garnettii 98.48 0.00e+00 2084.00
IUUC-Oar-090449 Ovis aries 97.52 0.00e+00 2074.00
IUUC-Pan-092135 Papio anubis 99.43 0.00e+00 2100.00
IUUC-Psi-093832 Pelodiscus sinensis 85.35 0.00e+00 1870.00
IUUC-Pfo-097268 Poecilia formosa 65.43 0.00e+00 1384.00
IUUC-Pca-100855 Procavia capensis 93.58 0.00e+00 1426.00
IUUC-Pva-102506 Pteropus vampyrus 89.53 0.00e+00 1836.00
IUUC-Rno-105242 Rattus norvegicus 95.33 0.00e+00 2078.00
IUUC-Sha-107186 Sarcophilus harrisii 89.24 0.00e+00 1200.00
IUUC-Sar-113612 Sorex araneus 95.40 0.00e+00 746.00
IUUC-Ssc-115473 Sus scrofa 97.43 0.00e+00 2071.00
IUUC-Tgu-116974 Taeniopygia guttata 87.92 0.00e+00 1851.00
IUUC-Tru-118077 Takifugu rubripes 63.46 0.00e+00 1317.00
IUUC-Tsy-119619 Tarsius syrichta 86.95 0.00e+00 1852.00
IUUC-Tni-120807 Tetraodon nigroviridis 63.64 0.00e+00 1340.00
IUUC-Tbe-127640 Tupaia belangeri 94.48 0.00e+00 1951.00
IUUC-Ttr-129172 Tursiops truncatus 97.14 0.00e+00 2060.00
IUUC-Vpa-130442 Vicugna pacos 82.77 0.00e+00 1699.00
IUUC-Xtr-132194 Xenopus tropicalis 71.36 0.00e+00 1439.00
Created Date 25-Jun-2017

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