iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033213

UUCD1 version

UUC-EqC-00796

Ensembl Protein ID

ENSECAP00000015871.1

UniProt Accession

F7CI74; F7CI74_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL23

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018323.1	ENSECAT00000019394.1	ENSECAP00000015871.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.70e-16	59.8	36	102
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.10e-08	31.4	137	166

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +D++l++  g  f++h++vLaa+S +F+a+f+ +++e+  k++++i+++ ++ ++ l+++ Yt+++++
   Q: 36   TDITLQCPsGIIFHCHRAVLAACSNYFKAMFTADMKEKF-KNKIKISGIHHDILEGLVNYAYTSQIEI 102
           6999*9999*****************************9.************************9976 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           +Nc+g+ +fA+ + cp+L +  ++ +++ F
   Q: 137  DNCIGMHSFAEFHVCPELEKESRRILCSRF 166
           8******************99988777666 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MALKGQEDYI YLFKDSAHPV DFLDAFRTFY LDGLFTDITL QCPSGIIFHC HRAVLAACSN 60
YFKAMFTADM KEKFKNKIKI SGIHHDILEG LVNYAYTSQI EITKRNVQSL LEAADLLQFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTGTTCCCC AATATAGAGT AGGAGCATTG TTGGCTAGAA ACTGGCTGGT GTTTAAAACT 60
GAAGGTTGTC AGGACTGTTT AACCTAAGCT GTATGCTGAA GTAAGATTAA TTGTCTTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

ecb:100052649

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001639	Ailuropoda melanoleuca	99.46	0.00e+00	1157.00
IUUC-Apl-003948	Anas platyrhynchos	77.06	0.00e+00	856.00
IUUC-Aca-005045	Anolis carolinensis	77.42	0.00e+00	934.00
IUUC-Ame-011013	Astyanax mexicanus	62.57	0.00e+00	769.00
IUUC-Bta-013159	Bos taurus	98.39	0.00e+00	1151.00
IUUC-Cja-018886	Callithrix jacchus	98.03	0.00e+00	1150.00
IUUC-Cfa-020205	Canis familiaris	99.64	0.00e+00	1162.00
IUUC-Cpo-022295	Cavia porcellus	97.49	0.00e+00	1137.00
IUUC-Cho-025089	Choloepus hoffmanni	97.36	0.00e+00	931.00
IUUC-Dre-027681	Danio rerio	59.82	0.00e+00	740.00
IUUC-Dno-029078	Dasypus novemcinctus	97.14	0.00e+00	929.00
IUUC-Ete-033011	Echinops telfairi	86.05	0.00e+00	969.00
IUUC-Fca-035884	Felis catus	99.10	0.00e+00	1156.00
IUUC-Fal-036897	Ficedula albicollis	77.44	0.00e+00	927.00
IUUC-Gmo-038594	Gadus morhua	57.19	0.00e+00	699.00
IUUC-Gga-040791	Gallus gallus	75.27	0.00e+00	927.00
IUUC-Gac-042512	Gasterosteus aculeatus	60.32	0.00e+00	739.00
IUUC-Ggo-044837	Gorilla gorilla	98.39	0.00e+00	1151.00
IUUC-Hsa-046231	Homo sapiens	98.75	0.00e+00	1156.00
IUUC-Itr-048084	Ictidomys tridecemlineatus	98.92	0.00e+00	1155.00
IUUC-Lch-050412	Latimeria chalumnae	72.60	0.00e+00	895.00
IUUC-Loc-052033	Lepisosteus oculatus	68.26	0.00e+00	832.00
IUUC-Laf-053908	Loxodonta africana	98.57	0.00e+00	1155.00
IUUC-Mcc-054734	Macaca mulatta	98.57	0.00e+00	1154.00
IUUC-Meu-055982	Macropus eugenii	89.43	0.00e+00	1066.00
IUUC-Mga-059670	Meleagris gallopavo	74.60	0.00e+00	916.00
IUUC-Mmr-060692	Microcebus murinus	98.39	0.00e+00	1153.00
IUUC-Mdo-062419	Monodelphis domestica	89.96	0.00e+00	1072.00
IUUC-Mmu-063752	Mus musculus	97.13	0.00e+00	1143.00
IUUC-Mpu-066515	Mustela putorius furo	99.46	0.00e+00	1160.00
IUUC-Mlu-068004	Myotis lucifugus	95.51	0.00e+00	1111.00
IUUC-Nle-069163	Nomascus leucogenys	98.75	0.00e+00	1156.00
IUUC-Opr-070823	Ochotona princeps	97.36	0.00e+00	926.00
IUUC-Ont-071629	Oreochromis niloticus	61.74	0.00e+00	749.00
IUUC-Oan-072841	Ornithorhynchus anatinus	84.95	0.00e+00	1020.00
IUUC-Ocu-074300	Oryctolagus cuniculus	99.28	0.00e+00	1159.00
IUUC-Ola-087025	Oryzias latipes	57.83	0.00e+00	716.00
IUUC-Oga-088442	Otolemur garnettii	97.07	0.00e+00	1102.00
IUUC-Oar-089237	Ovis aries	98.39	0.00e+00	1148.00
IUUC-Ptr-091541	Pan troglodytes	98.57	0.00e+00	1154.00
IUUC-Psi-093748	Pelodiscus sinensis	77.96	0.00e+00	945.00
IUUC-Pma-094302	Petromyzon marinus	44.86	3.00e-100	358.00
IUUC-Pfo-097039	Poecilia formosa	61.15	0.00e+00	729.00
IUUC-Pab-098280	Pongo abelii	98.21	0.00e+00	1148.00
IUUC-Pca-100840	Procavia capensis	89.25	0.00e+00	1025.00
IUUC-Pva-102152	Pteropus vampyrus	98.57	0.00e+00	1149.00
IUUC-Rno-105710	Rattus norvegicus	97.30	0.00e+00	1140.00
IUUC-Sha-106991	Sarcophilus harrisii	89.43	0.00e+00	1067.00
IUUC-Sar-112931	Sorex araneus	98.03	0.00e+00	1151.00
IUUC-Ssc-116016	Sus scrofa	98.21	0.00e+00	1144.00
IUUC-Tgu-116999	Taeniopygia guttata	77.24	0.00e+00	932.00
IUUC-Tsy-119071	Tarsius syrichta	98.03	0.00e+00	1147.00
IUUC-Tni-120149	Tetraodon nigroviridis	55.78	0.00e+00	653.00
IUUC-Tbe-127651	Tupaia belangeri	99.46	0.00e+00	1159.00
IUUC-Ttr-128402	Tursiops truncatus	98.75	0.00e+00	1156.00
IUUC-Vpa-130186	Vicugna pacos	97.85	0.00e+00	1140.00
IUUC-Xtr-132379	Xenopus tropicalis	70.97	0.00e+00	879.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence