iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088767

Ensembl Protein ID

ENSOGAP00000011434.2

UniProt Accession

H0X7N4; H0X7N4_OTOGA

Genbank Protein ID

ENSOGAP00000011434

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AAQR03038296

Gene Name

ABL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000012757.2	ENSOGAT00000012760.2	ENSOGAP00000011434.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.70e-12	47.1	36	93

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 36   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 93
           67899************************.*********98..788899*********997 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

EALHRPYGCD VEPQALHEAI RWSSKENLLG ATESDPNLFV ALYDFVASGD NTLSITKGEK 60
LRVLGYNQNG EWSEVRSKNG QGWVPSNYIT PVNSLEKHSW YHGPVSRSAA EYLLSSLING 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGCCTTGC ATCGCCCCTA TGGTTGTGAT GTTGAACCCC AGGCACTGCA TGAAGCTATC 60
AGGTGGAGCT CCAAGGAGAA CTTGCTTGGA GCCACTGAGA GTGACCCTAA TCTCTTTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR033221--ABL1
IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005623--C:cell
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0071300--P:cellular response to retinoic acid
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002263	Ailuropoda melanoleuca	90.65	0.00e+00	1834.00
IUUC-Apl-003389	Anas platyrhynchos	79.50	0.00e+00	1585.00
IUUC-Ame-010629	Astyanax mexicanus	56.42	0.00e+00	1029.00
IUUC-Bta-013370	Bos taurus	90.47	0.00e+00	1812.00
IUUC-Cja-018894	Callithrix jacchus	90.63	0.00e+00	1829.00
IUUC-Cfa-020398	Canis familiaris	87.84	0.00e+00	1081.00
IUUC-Cpo-022367	Cavia porcellus	87.00	0.00e+00	1370.00
IUUC-Csa-023386	Chlorocebus sabaeus	91.37	0.00e+00	1846.00
IUUC-Cho-024714	Choloepus hoffmanni	86.06	0.00e+00	1720.00
IUUC-Dre-027741	Danio rerio	62.23	0.00e+00	1218.00
IUUC-Dno-029246	Dasypus novemcinctus	90.47	0.00e+00	1823.00
IUUC-Dor-030416	Dipodomys ordii	86.10	0.00e+00	1156.00
IUUC-Ete-032899	Echinops telfairi	71.25	0.00e+00	736.00
IUUC-Eca-033387	Equus caballus	91.37	0.00e+00	1801.00
IUUC-Eeu-035058	Erinaceus europaeus	82.55	0.00e+00	1704.00
IUUC-Fca-036578	Felis catus	83.99	0.00e+00	1638.00
IUUC-Fal-037491	Ficedula albicollis	82.24	0.00e+00	1713.00
IUUC-Gmo-038509	Gadus morhua	69.07	0.00e+00	965.00
IUUC-Gga-040638	Gallus gallus	81.33	0.00e+00	1660.00
IUUC-Gac-042550	Gasterosteus aculeatus	61.76	0.00e+00	1153.00
IUUC-Ggo-044487	Gorilla gorilla	91.19	0.00e+00	1842.00
IUUC-Hsa-046636	Homo sapiens	91.28	0.00e+00	1843.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	90.29	0.00e+00	1818.00
IUUC-Lch-049530	Latimeria chalumnae	72.35	0.00e+00	1421.00
IUUC-Loc-051933	Lepisosteus oculatus	64.55	0.00e+00	1279.00
IUUC-Laf-053802	Loxodonta africana	90.31	0.00e+00	1847.00
IUUC-Mcc-054836	Macaca mulatta	91.28	0.00e+00	1845.00
IUUC-Mga-059277	Meleagris gallopavo	82.05	0.00e+00	1680.00
IUUC-Mmr-061206	Microcebus murinus	90.74	0.00e+00	1744.00
IUUC-Mdo-062281	Monodelphis domestica	86.55	0.00e+00	1048.00
IUUC-Mmu-063847	Mus musculus	87.88	0.00e+00	1700.00
IUUC-Mpu-066309	Mustela putorius furo	87.52	0.00e+00	1078.00
IUUC-Mlu-068070	Myotis lucifugus	90.47	0.00e+00	1822.00
IUUC-Nle-070062	Nomascus leucogenys	88.17	0.00e+00	1085.00
IUUC-Opr-070534	Ochotona princeps	81.07	0.00e+00	908.00
IUUC-Ont-072440	Oreochromis niloticus	65.38	0.00e+00	1068.00
IUUC-Oan-073526	Ornithorhynchus anatinus	82.87	0.00e+00	1607.00
IUUC-Ocu-074051	Oryctolagus cuniculus	89.13	0.00e+00	1721.00
IUUC-Oar-089800	Ovis aries	90.38	0.00e+00	1816.00
IUUC-Ptr-090857	Pan troglodytes	88.17	0.00e+00	1084.00
IUUC-Pan-092279	Papio anubis	91.28	0.00e+00	1840.00
IUUC-Psi-093573	Pelodiscus sinensis	82.71	0.00e+00	1650.00
IUUC-Pfo-096543	Poecilia formosa	69.23	0.00e+00	976.00
IUUC-Pab-097949	Pongo abelii	91.28	0.00e+00	1805.00
IUUC-Pca-100370	Procavia capensis	86.81	0.00e+00	1309.00
IUUC-Pva-103220	Pteropus vampyrus	88.35	0.00e+00	946.00
IUUC-Rno-105924	Rattus norvegicus	86.42	0.00e+00	1704.00
IUUC-Sha-107114	Sarcophilus harrisii	80.54	0.00e+00	1253.00
IUUC-Ssc-115968	Sus scrofa	89.75	0.00e+00	1861.00
IUUC-Tgu-117301	Taeniopygia guttata	81.87	0.00e+00	1632.00
IUUC-Tru-118410	Takifugu rubripes	62.66	0.00e+00	1196.00
IUUC-Tni-119991	Tetraodon nigroviridis	62.61	0.00e+00	1203.00
IUUC-Tbe-127362	Tupaia belangeri	85.52	0.00e+00	1624.00
IUUC-Ttr-129291	Tursiops truncatus	90.20	0.00e+00	1817.00
IUUC-Vpa-130800	Vicugna pacos	89.44	0.00e+00	1384.00
IUUC-Xtr-132965	Xenopus tropicalis	63.78	0.00e+00	1212.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence