iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037107

Ensembl Protein ID

ENSFALP00000011030.1

UniProt Accession

U3K7M6; U3K7M6_FICAL

Genbank Protein ID

ENSFALP00000011030

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01012131

Gene Name

HCLS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000010574.1	ENSFALT00000011075.1	ENSFALP00000011030.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.60e-12	45.1	445	496

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +lydy++  dde ++   d++  i  e  degW++g    +g+ GlfP+n+v+ l
   Q: 445  VALYDYQGDGDDEISFDPEDTISHI--EMVDEGWWRG--WCRGRVGLFPANYVKLL 496
           58***********************..9*********..8*************977 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MWKAVVGHNV SVKVEPQGDD WDTDPDFVND ISEREQRWGA KTIEGSGHAG HIDIHQLRNK 60
VSEEHEVIKK KELETGPKSS YGYGGKFGTE QDRMDKCAVG HEYVAHVEKH SSQTDAAQGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTACAGGCC CAAAGCTCTC GCTGGCAGCA GGTGCCTGAG CAAATAGCAG CGAGTTTCTC 60
AGCAGGAACT TGTGAGCCTT TAAAGGTAAG AAAACTTGGG GGAGTTTTGG GAGCGAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

KEGG

fab:101805706

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004103	Anas platyrhynchos	59.32	1.00e-168	586.00
IUUC-Ame-011504	Astyanax mexicanus	61.80	6.00e-98	351.00
IUUC-Bta-012591	Bos taurus	57.33	1.00e-108	386.00
IUUC-Cja-019982	Callithrix jacchus	55.87	1.00e-106	379.00
IUUC-Cpo-021362	Cavia porcellus	67.61	3.00e-108	385.00
IUUC-Csa-023911	Chlorocebus sabaeus	57.22	7.00e-110	390.00
IUUC-Dor-030437	Dipodomys ordii	45.94	7.00e-83	300.00
IUUC-Ete-033160	Echinops telfairi	42.88	8.00e-91	327.00
IUUC-Eeu-035032	Erinaceus europaeus	39.01	2.00e-57	216.00
IUUC-Fca-035999	Felis catus	55.33	3.00e-108	385.00
IUUC-Gga-040335	Gallus gallus	89.82	4.00e-144	504.00
IUUC-Ggo-044505	Gorilla gorilla	54.90	8.00e-109	387.00
IUUC-Itr-048592	Ictidomys tridecemlineatus	60.24	6.00e-103	367.00
IUUC-Laf-054202	Loxodonta africana	67.26	3.00e-106	378.00
IUUC-Mcc-055824	Macaca mulatta	57.73	6.00e-111	394.00
IUUC-Mdo-062515	Monodelphis domestica	49.62	1.00e-118	419.00
IUUC-Nle-069436	Nomascus leucogenys	57.22	3.00e-110	392.00
IUUC-Opr-070288	Ochotona princeps	59.79	2.00e-81	296.00
IUUC-Ocu-074686	Oryctolagus cuniculus	67.97	1.00e-107	383.00
IUUC-Ola-086894	Oryzias latipes	64.81	5.00e-98	351.00
IUUC-Oar-089686	Ovis aries	52.53	1.00e-131	463.00
IUUC-Ptr-090461	Pan troglodytes	57.47	4.00e-110	391.00
IUUC-Pan-091887	Papio anubis	57.22	5.00e-110	390.00
IUUC-Psi-093785	Pelodiscus sinensis	62.66	7.00e-174	603.00
IUUC-Pab-098222	Pongo abelii	56.19	2.00e-108	385.00
IUUC-Pca-100668	Procavia capensis	51.69	3.00e-128	451.00
IUUC-Pva-102767	Pteropus vampyrus	55.16	6.00e-82	297.00
IUUC-Rno-106001	Rattus norvegicus	52.69	5.00e-129	454.00
IUUC-Sar-113338	Sorex araneus	58.43	4.00e-78	285.00
IUUC-Ssc-116027	Sus scrofa	51.76	2.00e-127	448.00
IUUC-Tgu-117472	Taeniopygia guttata	68.34	0.00e+00	667.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence