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Tag Content
UUCD2 ID IUUC-Ocu-074194
UUCD1 version UUC-OrC-00746
Ensembl Protein ID ENSOCUP00000000153.2
UniProt Accession G1SCR8; G1SCR8_RABIT
Genbank Protein ID ENSOCUP00000000153
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAGW02001010
Gene Name VAV3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOCUG00000000172.4 ENSOCUT00000000172.3 ENSOCUP00000000153.2
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.20e-14 54.0 794 845
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ yd+ a +  eL+l kGdvv++   +   +gW++g  e +g+ G fP+ +ve+
   Q: 794  IARYDFCARDMRELSLLKGDVVKIY-TKMSANGWWRG--EVNGRVGWFPSTYVEE 845
           688*********************9.999999*****..9*************86 PP
   
Organism Oryctolagus cuniculus
Protein Sequence
(Fasta)
MEPWRQCAQW LIHCKVLPAN HRVTWDSAQV FDLAQTLRDG VLLCQLLNNL RAHSINLKEI 60
NLRPQMSQFL CLKNIRTFLT ACCETFGMRK SELFEAFDLF DVRDFGKVIE TLSRLSRTPI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ocu-074194|UBD,SH3|Oryctolagus cuniculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCGCGAGTC GGAAGCCTGT GCGCGGCAGC CGCTGCCGCC GAGCCGGCCG GGGCGCACGG 60
AGAGCGCGCG GGACTCGCTG CAGCGGCGGC CGGGCCGCGG CGGACCGGGG CCGGGGCCGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ocu-074194|UBD,SH3|Oryctolagus cuniculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc
Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain
IPR003096--SM22_calponin
PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2
Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2
PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00888--SM22CALPONIN
SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3
Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0046872--F:metal ion binding
GO:0030676--F:Rac guanyl-nucleotide exchange factor activity
GO:0050853--P:B cell receptor signaling pathway
GO:0006974--P:cellular response to DNA damage stimulus
GO:0007229--P:integrin-mediated signaling pathway
GO:0030032--P:lamellipodium assembly
GO:0030593--P:neutrophil chemotaxis
GO:0030890--P:positive regulation of B cell proliferation
GO:0045785--P:positive regulation of cell adhesion
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0008361--P:regulation of cell size
GO:0035023--P:regulation of Rho protein signal transduction
GO:0042493--P:response to drug
GO:0007264--P:small GTPase mediated signal transduction
GO:0006906--P:vesicle fusion
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001362 Ailuropoda melanoleuca 96.69 0.00e+00 1615.00
IUUC-Apl-003734 Anas platyrhynchos 86.91 0.00e+00 1360.00
IUUC-Aca-004477 Anolis carolinensis 82.63 0.00e+00 1405.00
IUUC-Ame-011279 Astyanax mexicanus 66.43 0.00e+00 1115.00
IUUC-Bta-012722 Bos taurus 95.63 0.00e+00 1599.00
IUUC-Cel-018578 Caenorhabditis elegans 29.05 5.00e-73 269.00
IUUC-Cja-018941 Callithrix jacchus 97.74 0.00e+00 1610.00
IUUC-Cfa-020266 Canis familiaris 96.97 0.00e+00 1441.00
IUUC-Cpo-021966 Cavia porcellus 95.99 0.00e+00 1393.00
IUUC-Csa-023892 Chlorocebus sabaeus 96.93 0.00e+00 1483.00
IUUC-Cin-025115 Ciona intestinalis 36.87 2.00e-135 476.00
IUUC-Csv-025995 Ciona savignyi 35.69 4.00e-148 518.00
IUUC-Dre-028199 Danio rerio 66.25 0.00e+00 1113.00
IUUC-Dno-029474 Dasypus novemcinctus 96.69 0.00e+00 1619.00
IUUC-Dor-031014 Dipodomys ordii 45.09 0.00e+00 630.00
IUUC-Eca-033961 Equus caballus 96.97 0.00e+00 1466.00
IUUC-Eeu-034719 Erinaceus europaeus 69.78 0.00e+00 1088.00
IUUC-Fca-036572 Felis catus 96.41 0.00e+00 1576.00
IUUC-Fal-036802 Ficedula albicollis 85.14 0.00e+00 1490.00
IUUC-Gmo-039409 Gadus morhua 69.57 0.00e+00 1165.00
IUUC-Gga-040884 Gallus gallus 85.95 0.00e+00 1475.00
IUUC-Gac-041395 Gasterosteus aculeatus 71.56 0.00e+00 1242.00
IUUC-Ggo-044460 Gorilla gorilla 95.01 0.00e+00 1405.00
IUUC-Hsa-046099 Homo sapiens 94.29 0.00e+00 1610.00
IUUC-Itr-048144 Ictidomys tridecemlineatus 93.00 0.00e+00 1405.00
IUUC-Lch-049650 Latimeria chalumnae 82.16 2.00e-109 387.00
IUUC-Loc-052487 Lepisosteus oculatus 73.51 0.00e+00 1247.00
IUUC-Laf-054564 Loxodonta africana 95.28 0.00e+00 1595.00
IUUC-Mcc-054622 Macaca mulatta 93.94 0.00e+00 1605.00
IUUC-Meu-056680 Macropus eugenii 85.83 0.00e+00 1423.00
IUUC-Mga-060013 Meleagris gallopavo 82.15 0.00e+00 1393.00
IUUC-Mmr-061251 Microcebus murinus 92.62 0.00e+00 1627.00
IUUC-Mdo-061875 Monodelphis domestica 93.51 0.00e+00 1575.00
IUUC-Mmu-063735 Mus musculus 95.99 0.00e+00 1626.00
IUUC-Mpu-065856 Mustela putorius furo 96.81 0.00e+00 1614.00
IUUC-Mlu-068108 Myotis lucifugus 91.31 0.00e+00 1531.00
IUUC-Nle-069863 Nomascus leucogenys 93.10 0.00e+00 1573.00
IUUC-Opr-070372 Ochotona princeps 85.89 0.00e+00 1072.00
IUUC-Ont-072286 Oreochromis niloticus 71.99 0.00e+00 1235.00
IUUC-Oan-073384 Ornithorhynchus anatinus 49.04 0.00e+00 654.00
IUUC-Ola-086336 Oryzias latipes 70.47 0.00e+00 1217.00
IUUC-Oar-089272 Ovis aries 95.51 0.00e+00 1635.00
IUUC-Ptr-090652 Pan troglodytes 95.29 0.00e+00 1611.00
IUUC-Pan-092550 Papio anubis 93.27 0.00e+00 1417.00
IUUC-Psi-093784 Pelodiscus sinensis 80.94 0.00e+00 1270.00
IUUC-Pma-094372 Petromyzon marinus 50.07 0.00e+00 647.00
IUUC-Ppa-095161 Physcomitrella patens 43.64 3.00e-09 56.20
IUUC-Pfo-097308 Poecilia formosa 69.44 0.00e+00 1221.00
IUUC-Pab-098698 Pongo abelii 95.28 0.00e+00 1611.00
IUUC-Pca-100295 Procavia capensis 51.08 0.00e+00 785.00
IUUC-Pva-102262 Pteropus vampyrus 96.64 0.00e+00 1551.00
IUUC-Rno-105421 Rattus norvegicus 95.28 0.00e+00 1630.00
IUUC-Sha-107325 Sarcophilus harrisii 93.51 0.00e+00 1592.00
IUUC-Sar-113456 Sorex araneus 90.91 0.00e+00 1533.00
IUUC-Tgu-116595 Taeniopygia guttata 83.53 0.00e+00 1396.00
IUUC-Tru-117884 Takifugu rubripes 66.63 0.00e+00 1196.00
IUUC-Tsy-119429 Tarsius syrichta 88.58 0.00e+00 1333.00
IUUC-Tni-119951 Tetraodon nigroviridis 69.01 0.00e+00 1154.00
IUUC-Tbe-127995 Tupaia belangeri 85.00 5.00e-178 618.00
IUUC-Ttr-128281 Tursiops truncatus 95.99 0.00e+00 1600.00
IUUC-Xtr-132427 Xenopus tropicalis 72.86 0.00e+00 1291.00
Created Date 25-Jun-2017

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