iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000005525.1	ENSPSIT00000006147.1	ENSPSIP00000006110.1
ENSPSIG00000005525.1	ENSPSIT00000006151.1	ENSPSIP00000006114.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.00e-15	55.0	755	806

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ yd+ a +  eL+l kGdvv++   +   +gW++g  e +g+ G fP+ +ve+
   Q: 755  IARYDFCARDMRELSLVKGDVVKIY-TKMSANGWWRG--EVNGRMGWFPSTYVEE 806
           578*********************9.999999*****..9*************86 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

FLCLKNIRTF LSACCEIFGM KKSELFEAFD LFDVRDFGKV IETLSKLSRT PIALVTGIRP 60
FPTEESVNDE DIYKGLPDLL DENGVDEDEE LYDCVYGEDE GGEVYEDLMK DEAPHQPKCI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCTCTGCT TGAAGAATAT AAGAACATTC CTTTCAGCAT GCTGTGAGAT ATTTGGGATG 60
AAGAAAAGTG AACTTTTTGA AGCATTTGAT TTGTTTGACG TGCGGGATTT TGGAAAGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR017868--Filamin/ABP280_repeat-like
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50194--FILAMIN_REPEAT
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00307--CH
PF00630--Filamin
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0046872--F:metal ion binding
GO:0030676--F:Rac guanyl-nucleotide exchange factor activity
GO:0050853--P:B cell receptor signaling pathway
GO:0006974--P:cellular response to DNA damage stimulus
GO:0007229--P:integrin-mediated signaling pathway
GO:0030032--P:lamellipodium assembly
GO:0030593--P:neutrophil chemotaxis
GO:0030890--P:positive regulation of B cell proliferation
GO:0045785--P:positive regulation of cell adhesion
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0008361--P:regulation of cell size
GO:0035023--P:regulation of Rho protein signal transduction
GO:0042493--P:response to drug
GO:0007264--P:small GTPase mediated signal transduction
GO:0006906--P:vesicle fusion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001362	Ailuropoda melanoleuca	81.44	0.00e+00	1279.00
IUUC-Apl-003734	Anas platyrhynchos	86.01	0.00e+00	1370.00
IUUC-Aca-004477	Anolis carolinensis	86.51	0.00e+00	1362.00
IUUC-Ath-007340	Arabidopsis thaliana	50.00	1.30e-02	33.90
IUUC-Ame-011279	Astyanax mexicanus	62.22	0.00e+00	959.00
IUUC-Bta-012722	Bos taurus	80.69	0.00e+00	1264.00
IUUC-Cja-018941	Callithrix jacchus	80.94	0.00e+00	1272.00
IUUC-Cfa-020266	Canis familiaris	81.37	0.00e+00	1242.00
IUUC-Cpo-021966	Cavia porcellus	79.95	0.00e+00	1195.00
IUUC-Csa-023892	Chlorocebus sabaeus	80.57	0.00e+00	1273.00
IUUC-Dre-028199	Danio rerio	65.31	0.00e+00	1019.00
IUUC-Dno-029474	Dasypus novemcinctus	81.31	0.00e+00	1280.00
IUUC-Eca-033961	Equus caballus	81.12	0.00e+00	1263.00
IUUC-Eeu-034719	Erinaceus europaeus	55.82	0.00e+00	792.00
IUUC-Fca-036572	Felis catus	80.69	0.00e+00	1260.00
IUUC-Fal-036802	Ficedula albicollis	89.85	0.00e+00	1449.00
IUUC-Gmo-039409	Gadus morhua	65.47	0.00e+00	1026.00
IUUC-Gga-040884	Gallus gallus	85.15	0.00e+00	1353.00
IUUC-Gac-041395	Gasterosteus aculeatus	67.61	0.00e+00	1086.00
IUUC-Ggo-044460	Gorilla gorilla	79.27	0.00e+00	1208.00
IUUC-Hsa-046099	Homo sapiens	84.65	0.00e+00	1355.00
IUUC-Itr-048144	Ictidomys tridecemlineatus	84.33	0.00e+00	1311.00
IUUC-Lch-049650	Latimeria chalumnae	71.67	4.00e-101	360.00
IUUC-Loc-052487	Lepisosteus oculatus	69.02	0.00e+00	1095.00
IUUC-Laf-054564	Loxodonta africana	80.82	0.00e+00	1264.00
IUUC-Mcc-054622	Macaca mulatta	84.03	0.00e+00	1348.00
IUUC-Meu-056680	Macropus eugenii	73.39	0.00e+00	1134.00
IUUC-Mga-060013	Meleagris gallopavo	83.03	0.00e+00	1306.00
IUUC-Mmr-061251	Microcebus murinus	83.31	0.00e+00	1376.00
IUUC-Mdo-061875	Monodelphis domestica	80.32	0.00e+00	1269.00
IUUC-Mmu-063735	Mus musculus	80.20	0.00e+00	1286.00
IUUC-Mpu-065856	Mustela putorius furo	81.56	0.00e+00	1282.00
IUUC-Mlu-068108	Myotis lucifugus	82.67	0.00e+00	1247.00
IUUC-Nle-069863	Nomascus leucogenys	84.03	0.00e+00	1343.00
IUUC-Opr-070372	Ochotona princeps	70.93	0.00e+00	778.00
IUUC-Ont-072286	Oreochromis niloticus	68.39	0.00e+00	1085.00
IUUC-Ocu-074194	Oryctolagus cuniculus	80.94	0.00e+00	1276.00
IUUC-Ola-086336	Oryzias latipes	67.24	0.00e+00	1092.00
IUUC-Olu-087747	Ostreococcus lucimarinus	41.46	3.50e-01	28.90
IUUC-Oar-089272	Ovis aries	80.57	0.00e+00	1304.00
IUUC-Ptr-090652	Pan troglodytes	78.89	0.00e+00	1258.00
IUUC-Pan-092550	Papio anubis	83.90	0.00e+00	1310.00
IUUC-Pfo-097308	Poecilia formosa	71.39	0.00e+00	1153.00
IUUC-Pab-098698	Pongo abelii	78.71	0.00e+00	1257.00
IUUC-Pva-102262	Pteropus vampyrus	80.63	0.00e+00	1215.00
IUUC-Rno-105421	Rattus norvegicus	79.83	0.00e+00	1286.00
IUUC-Sha-107325	Sarcophilus harrisii	80.57	0.00e+00	1290.00
IUUC-Sar-113456	Sorex araneus	75.50	0.00e+00	1199.00
IUUC-Tgu-116595	Taeniopygia guttata	82.90	0.00e+00	1299.00
IUUC-Tru-118577	Takifugu rubripes	68.11	0.00e+00	1113.00
IUUC-Tsy-119429	Tarsius syrichta	74.88	0.00e+00	1155.00
IUUC-Tni-119951	Tetraodon nigroviridis	64.79	0.00e+00	986.00
IUUC-Tbe-127995	Tupaia belangeri	76.35	3.00e-138	485.00
IUUC-Ttr-128281	Tursiops truncatus	81.06	0.00e+00	1269.00
IUUC-Xtr-132427	Xenopus tropicalis	67.40	0.00e+00	1117.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence