iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033717

UUCD1 version

UUC-EqC-00667

Ensembl Protein ID

ENSECAP00000011833.1

UniProt Accession

F7APX2; F7APX2_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRAF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000013973.1	ENSECAT00000014786.1	ENSECAP00000011833.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	96.83	0.00e+00	1151.00	IUUC-Hsa-046957

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MESSKKMDSP GALQTNPPLK LHPDRSTSTA VFVPEQGGYK ERFVKTVEDK YKCEKCRLVL 60
CNPKQTECGH RFCETCMAAL LSSSSPKCTA CQEGIIKDKV FKDNCCKREI LALQIYCRNE 120

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Nucleotide Sequence
(Fasta)

ATGGAGTCGA GTAAGAAGAT GGACTCCCCT GGCGCCCTGC AGACTAACCC GCCGCTAAAG 60
CTGCACCCTG ACCGCAGCAC CAGCACGGCA GTTTTCGTCC CTGAACAAGG AGGTTACAAA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027128--TRAF3
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042981--P:regulation of apoptotic process
GO:0050688--P:regulation of defense response to virus
GO:0032648--P:regulation of interferon-beta production
GO:0030162--P:regulation of proteolysis
GO:0008063--P:Toll signaling pathway
GO:0002224--P:toll-like receptor signaling pathway
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

KEGG

ecb:100055110

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002362	Ailuropoda melanoleuca	97.54	0.00e+00	1158.00
IUUC-Apl-004189	Anas platyrhynchos	88.38	0.00e+00	1065.00
IUUC-Aca-004540	Anolis carolinensis	85.04	0.00e+00	1025.00
IUUC-Ame-010645	Astyanax mexicanus	57.96	0.00e+00	649.00
IUUC-Bta-013140	Bos taurus	95.60	0.00e+00	1137.00
IUUC-Cja-019436	Callithrix jacchus	96.83	0.00e+00	1150.00
IUUC-Cfa-021072	Canis familiaris	97.36	0.00e+00	1159.00
IUUC-Cpo-022472	Cavia porcellus	95.42	0.00e+00	1130.00
IUUC-Csa-024217	Chlorocebus sabaeus	96.48	0.00e+00	1148.00
IUUC-Cho-025066	Choloepus hoffmanni	83.06	0.00e+00	840.00
IUUC-Cin-025234	Ciona intestinalis	29.39	2.00e-53	203.00
IUUC-Csv-026078	Ciona savignyi	68.54	7.00e-80	289.00
IUUC-Dre-028208	Danio rerio	55.23	2.00e-177	615.00
IUUC-Dno-028868	Dasypus novemcinctus	95.07	0.00e+00	1137.00
IUUC-Dor-031056	Dipodomys ordii	97.12	0.00e+00	986.00
IUUC-Ete-033005	Echinops telfairi	82.91	0.00e+00	796.00
IUUC-Eeu-035172	Erinaceus europaeus	85.45	0.00e+00	637.00
IUUC-Fca-035688	Felis catus	97.36	0.00e+00	1154.00
IUUC-Fal-037176	Ficedula albicollis	88.03	0.00e+00	1060.00
IUUC-Gmo-038931	Gadus morhua	56.24	1.00e-170	592.00
IUUC-Ggr-040084	Gaeumannomyces graminis	26.00	2.00e-11	63.90
IUUC-Gac-042019	Gasterosteus aculeatus	56.51	4.00e-179	620.00
IUUC-Ggo-044424	Gorilla gorilla	97.18	0.00e+00	1155.00
IUUC-Hsa-046957	Homo sapiens	96.83	0.00e+00	1151.00
IUUC-Itr-048352	Ictidomys tridecemlineatus	96.30	0.00e+00	1140.00
IUUC-Kpa-049340	Komagataella pastoris	19.33	1.00e-07	51.20
IUUC-Lch-050680	Latimeria chalumnae	68.84	0.00e+00	835.00
IUUC-Loc-052093	Lepisosteus oculatus	57.27	0.00e+00	691.00
IUUC-Laf-054573	Loxodonta africana	87.50	0.00e+00	1025.00
IUUC-Mcc-055049	Macaca mulatta	96.13	0.00e+00	1143.00
IUUC-Mor-057263	Magnaporthe oryzae	22.27	6.00e-15	75.50
IUUC-Mpo-057517	Magnaporthe poae	25.00	3.00e-10	60.10
IUUC-Mga-059244	Meleagris gallopavo	87.68	0.00e+00	1061.00
IUUC-Mmr-061469	Microcebus murinus	97.36	0.00e+00	1155.00
IUUC-Mdo-063049	Monodelphis domestica	92.78	0.00e+00	1103.00
IUUC-Mmu-063763	Mus musculus	95.77	0.00e+00	1136.00
IUUC-Mpu-065956	Mustela putorius furo	96.13	0.00e+00	1114.00
IUUC-Mlu-067482	Myotis lucifugus	93.84	0.00e+00	1122.00
IUUC-Nle-069941	Nomascus leucogenys	96.83	0.00e+00	1152.00
IUUC-Opr-071027	Ochotona princeps	82.04	0.00e+00	916.00
IUUC-Ont-071914	Oreochromis niloticus	57.35	0.00e+00	661.00
IUUC-Oan-072802	Ornithorhynchus anatinus	92.43	0.00e+00	1097.00
IUUC-Ocu-074075	Oryctolagus cuniculus	96.83	0.00e+00	1152.00
IUUC-Oga-088149	Otolemur garnettii	97.01	0.00e+00	1155.00
IUUC-Oar-089922	Ovis aries	91.43	0.00e+00	1077.00
IUUC-Ptr-091412	Pan troglodytes	97.01	0.00e+00	1153.00
IUUC-Pan-092789	Papio anubis	96.48	0.00e+00	1148.00
IUUC-Psi-093603	Pelodiscus sinensis	85.74	0.00e+00	1032.00
IUUC-Pma-094463	Petromyzon marinus	49.37	1.00e-140	492.00
IUUC-Pfo-096518	Poecilia formosa	55.79	0.00e+00	647.00
IUUC-Pab-097664	Pongo abelii	97.18	0.00e+00	1155.00
IUUC-Pca-100821	Procavia capensis	85.60	0.00e+00	856.00
IUUC-Pva-103201	Pteropus vampyrus	84.51	0.00e+00	987.00
IUUC-Rno-105505	Rattus norvegicus	95.42	0.00e+00	1133.00
IUUC-Sha-107416	Sarcophilus harrisii	92.61	0.00e+00	1099.00
IUUC-Sar-113438	Sorex araneus	94.62	1.00e-101	363.00
IUUC-Ssc-115351	Sus scrofa	96.65	0.00e+00	1147.00
IUUC-Tgu-116608	Taeniopygia guttata	90.35	0.00e+00	1057.00
IUUC-Tru-117964	Takifugu rubripes	57.33	0.00e+00	627.00
IUUC-Tni-120211	Tetraodon nigroviridis	55.99	0.00e+00	635.00
IUUC-Tbe-127700	Tupaia belangeri	79.06	2.00e-144	505.00
IUUC-Ttr-128450	Tursiops truncatus	92.50	1.00e-177	615.00
IUUC-Uma-129620	Ustilago maydis	26.60	1.00e-11	65.10
IUUC-Vda-129938	Verticillium dahliae	25.20	6.00e-20	92.00
IUUC-Vpa-130074	Vicugna pacos	98.41	0.00e+00	902.00
IUUC-Xtr-132563	Xenopus tropicalis	79.58	0.00e+00	967.00
IUUC-Xma-133628	Xiphophorus maculatus	55.79	0.00e+00	646.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence