iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
IID	iRefIndex	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/UBX	1.10e-10	42.3	391	463

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/UBX

   S: 6    atlqiRlpdGkr.lvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           ++l+i+ ++G++ +  ++++++t+ ++++ +++++ ++s  Fe++s+fP   + +++   tlq agLvp+++ll+
   Q: 391  SMLRIKSENGEQaFLLMMRPEDTIGDVRNLLAQARDMDSAAFEILSTFPPTVYRDDTV--TLQAAGLVPNATLLL 463
           79**********9*********************************************..*************97 PP

Organism

Rattus norvegicus

Functional Description
(View)

May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13.

Protein Sequence
(Fasta)

MSSPLASLSK TRKVPLESEP VNPGRRGIRI YGDEDEVDMV NDGQDSEEKI SLPSCYGGIG 60
RQGLMIHDSE LLTSMARKLQ ELEQQLKARN EEMLSKEQKI LALEDLVQTL QQHQSSTTRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCCGAGAC AACAAGATGG CGGCGCCGCG GGACGGCTCG CTGGCCCCGT GGTGAGTCCC 60
AGCTCCGGAT CTTTCTGCCC CTCTAAGTCT TCCGGCAGAC CGCGGCCCTC GTCCGGACTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR012989--SEP_domain
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS51399--SEP
PS50033--UBX

Pfam

PF08059--SEP
PF00789--UBX

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0043130--F:ubiquitin binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

rno:192207

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002106	Ailuropoda melanoleuca	74.47	0.00e+00	686.00
IUUC-Apl-004013	Anas platyrhynchos	44.25	1.00e-88	320.00
IUUC-Aca-004665	Anolis carolinensis	48.96	4.00e-58	217.00
IUUC-Aly-005847	Arabidopsis lyrata	30.77	4.00e-03	35.40
IUUC-Ath-006745	Arabidopsis thaliana	27.96	4.00e-03	35.00
IUUC-Ame-011360	Astyanax mexicanus	31.61	1.00e-46	180.00
IUUC-Bta-013401	Bos taurus	74.64	0.00e+00	718.00
IUUC-Bol-015349	Brassica oleracea	28.40	3.00e-03	35.80
IUUC-Cja-018782	Callithrix jacchus	75.78	0.00e+00	748.00
IUUC-Cfa-020771	Canis familiaris	70.59	0.00e+00	642.00
IUUC-Cpo-022096	Cavia porcellus	76.30	0.00e+00	684.00
IUUC-Cre-022692	Chlamydomonas reinhardtii	38.99	4.00e-20	92.40
IUUC-Csa-024247	Chlorocebus sabaeus	79.96	0.00e+00	741.00
IUUC-Cin-025602	Ciona intestinalis	38.61	6.00e-77	281.00
IUUC-Csv-026269	Ciona savignyi	37.66	3.00e-12	63.20
IUUC-Dre-027891	Danio rerio	35.57	5.00e-75	275.00
IUUC-Dno-029857	Dasypus novemcinctus	80.00	4.00e-132	464.00
IUUC-Dor-030412	Dipodomys ordii	77.87	4.00e-154	537.00
IUUC-Ete-032458	Echinops telfairi	70.42	8.00e-115	406.00
IUUC-Eca-033588	Equus caballus	65.76	9.00e-177	612.00
IUUC-Eeu-034987	Erinaceus europaeus	70.00	2.00e-55	209.00
IUUC-Fca-036191	Felis catus	77.16	0.00e+00	710.00
IUUC-Fal-036787	Ficedula albicollis	43.00	1.00e-68	253.00
IUUC-Gmo-039684	Gadus morhua	38.31	7.00e-63	234.00
IUUC-Ggo-045292	Gorilla gorilla	80.39	0.00e+00	760.00
IUUC-Hsa-046321	Homo sapiens	80.82	0.00e+00	763.00
IUUC-Itr-048346	Ictidomys tridecemlineatus	75.79	0.00e+00	709.00
IUUC-Lch-050451	Latimeria chalumnae	37.45	2.00e-87	316.00
IUUC-Loc-052426	Lepisosteus oculatus	45.28	6.00e-80	291.00
IUUC-Laf-054529	Loxodonta africana	74.74	0.00e+00	742.00
IUUC-Mcc-055816	Macaca mulatta	84.17	3.00e-139	488.00
IUUC-Meu-056554	Macropus eugenii	53.85	1.00e-62	233.00
IUUC-Mga-059465	Meleagris gallopavo	42.93	9.00e-86	310.00
IUUC-Mmr-061200	Microcebus murinus	81.65	0.00e+00	789.00
IUUC-Mdo-062251	Monodelphis domestica	49.03	3.00e-111	395.00
IUUC-Mmu-063748	Mus musculus	87.37	0.00e+00	815.00
IUUC-Mpu-065893	Mustela putorius furo	70.31	0.00e+00	706.00
IUUC-Mlu-067272	Myotis lucifugus	71.55	0.00e+00	645.00
IUUC-Nle-069502	Nomascus leucogenys	77.22	0.00e+00	742.00
IUUC-Opr-070633	Ochotona princeps	74.30	2.00e-113	401.00
IUUC-Ont-071974	Oreochromis niloticus	35.15	3.00e-77	282.00
IUUC-Ocu-073992	Oryctolagus cuniculus	78.28	0.00e+00	743.00
IUUC-Oga-088667	Otolemur garnettii	76.76	0.00e+00	760.00
IUUC-Oar-089434	Ovis aries	71.40	0.00e+00	647.00
IUUC-Ptr-090611	Pan troglodytes	80.39	0.00e+00	754.00
IUUC-Pan-092364	Papio anubis	79.32	0.00e+00	707.00
IUUC-Psi-093473	Pelodiscus sinensis	43.80	1.00e-104	373.00
IUUC-Pfo-096635	Poecilia formosa	33.00	2.00e-64	239.00
IUUC-Pab-097570	Pongo abelii	80.17	0.00e+00	761.00
IUUC-Pca-101026	Procavia capensis	73.04	5.00e-81	294.00
IUUC-Pva-102579	Pteropus vampyrus	67.92	6.00e-130	456.00
IUUC-Pte-104066	Pyrenophora teres	26.92	7.10e-01	30.80
IUUC-Sha-107615	Sarcophilus harrisii	47.97	8.00e-78	283.00
IUUC-Sar-113037	Sorex araneus	52.83	4.00e-113	401.00
IUUC-Tsy-119106	Tarsius syrichta	65.14	5.00e-99	354.00
IUUC-Ttr-128789	Tursiops truncatus	74.35	0.00e+00	672.00
IUUC-Xtr-131876	Xenopus tropicalis	40.80	8.00e-80	290.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence