iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098584

Ensembl Protein ID

ENSPPYP00000013285.2

UniProt Accession

H2P4N2; H2P4N2_PONAB

Genbank Protein ID

ENSPPYP00000013285

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01141651

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000011904.2	ENSPPYT00000013824.2	ENSPPYP00000013285.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.90e-16	59.9	319	375

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ + ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 319  RVRALYDYEGQEHDELSFKAGDELTKM-EDEDEQGWCKG-RLDNGQVGLYPANYVEAIQ 375
           799***********************9.9**********.59*************9885 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSVTYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD VEAAKKAHHA ACKEEKLAIS 60
REANSKADPS LNPEQLKKLQ DKIEKCKQDV LKTKEKYEKS LKELDQGTPQ YMENMEQVFE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGGAGCGG CGAGGGCGGT GCGGTCGCGG CTGGCGGCAG AAGCGGCCGC AGGGGGTCTG 60
GGCAGGGCTG GGCAGTGCTG CCGGAGCAAA AGCGGGAGCG GGAGCCGGGC CGCAGCTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	92.90	3.00e-172	597.00
IUUC-Cja-018756	Callithrix jacchus	97.79	2.00e-166	578.00
IUUC-Cfa-020545	Canis familiaris	93.52	3.00e-173	601.00
IUUC-Cpo-022000	Cavia porcellus	87.80	9.00e-173	599.00
IUUC-Csa-024030	Chlorocebus sabaeus	98.11	3.00e-168	584.00
IUUC-Csv-026244	Ciona savignyi	43.07	3.00e-54	204.00
IUUC-Eca-033367	Equus caballus	90.43	8.00e-166	576.00
IUUC-Eeu-034821	Erinaceus europaeus	80.30	7.00e-139	487.00
IUUC-Fca-036079	Felis catus	94.14	2.00e-174	605.00
IUUC-Ggo-044841	Gorilla gorilla	99.37	3.00e-169	588.00
IUUC-Hsa-046411	Homo sapiens	99.68	2.00e-169	588.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	94.32	2.00e-166	578.00
IUUC-Mcc-055783	Macaca mulatta	98.74	2.00e-168	585.00
IUUC-Mvi-060548	Microbotryum violaceum	41.51	6.00e-07	50.40
IUUC-Mmr-060827	Microcebus murinus	93.83	6.00e-174	603.00
IUUC-Mmu-064109	Mus musculus	92.59	2.00e-171	595.00
IUUC-Mpu-066591	Mustela putorius furo	93.83	2.00e-174	605.00
IUUC-Mlu-067826	Myotis lucifugus	91.67	3.00e-170	591.00
IUUC-Nle-069797	Nomascus leucogenys	99.37	5.00e-169	587.00
IUUC-Oan-073076	Ornithorhynchus anatinus	84.35	2.00e-153	535.00
IUUC-Ocu-074425	Oryctolagus cuniculus	93.38	7.00e-168	583.00
IUUC-Oga-089009	Otolemur garnettii	83.86	3.00e-154	538.00
IUUC-Ptr-091111	Pan troglodytes	99.05	2.00e-168	585.00
IUUC-Pan-091749	Papio anubis	98.74	2.00e-168	585.00
IUUC-Pva-102649	Pteropus vampyrus	90.85	8.00e-165	573.00
IUUC-Sar-113461	Sorex araneus	75.31	9.00e-132	463.00
IUUC-Ssc-115349	Sus scrofa	93.19	3.00e-163	567.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence