iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117780

UUCD1 version

UUC-TaR-00416

Ensembl Protein ID

ENSTRUP00000020405.1

UniProt Accession

H2T6W6; H2T6W6_TAKRU

Protein Name

Uncharacterized protein

Gene Name

KLHL4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000008161.1	ENSTRUT00000020490.1	ENSTRUP00000020405.1
ENSTRUG00000008161.1	ENSTRUT00000020491.1	ENSTRUP00000020406.1
ENSTRUG00000008161.1	ENSTRUT00000020492.1	ENSTRUP00000020407.1
ENSTRUG00000008161.1	ENSTRUT00000020493.1	ENSTRUP00000020408.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.80e-20	73.7	220	287
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.10e-06	27.9	319	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+l+vg+ +++ah++vL+a S++F a+f+++ +e k ++++++++v+pe++r l++F Ytg l+++e
   Q: 220  CDVLLIVGDHKIPAHRLVLSAVSDYFAAMFTSDVREAK-QEEIKMEGVDPEALRSLVHFAYTGVLELKE 287
           9************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++fAd+ +c dL  +a++++  hF
   Q: 319  PSNCLGIRSFADAQGCVDLLNVAHNYTMEHF 349
           89************************98777 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSVSGKKEFD VKQILRLRWR WFSHSSQGSA GSGGGGIGGV GGYIQQDGLD HRGTPVQGRL 60
KSHSRERGGL LSSYWTKAPL KSCMQPRSSS LSLQSSAADT MDHLGTARRP QHEAHYKQSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGTGT CGGGGAAGAA GGAATTTGAT GTGAAGCAGA TCCTCAGGCT CCGCTGGCGT 60
TGGTTCAGTC ACTCGTCCCA AGGTTCTGCC GGCAGCGGGG GCGGCGGCAT TGGAGGAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004156	Anas platyrhynchos	87.50	0.00e+00	1021.00
IUUC-Aca-004238	Anolis carolinensis	83.88	0.00e+00	998.00
IUUC-Afl-008653	Aspergillus flavus	33.82	2.30e-01	29.60
IUUC-Ame-011287	Astyanax mexicanus	72.15	0.00e+00	925.00
IUUC-Cja-018916	Callithrix jacchus	68.11	0.00e+00	959.00
IUUC-Csa-023849	Chlorocebus sabaeus	69.41	0.00e+00	1009.00
IUUC-Dno-029854	Dasypus novemcinctus	65.79	0.00e+00	911.00
IUUC-Dor-030708	Dipodomys ordii	64.72	0.00e+00	902.00
IUUC-Ete-033156	Echinops telfairi	60.36	2.00e-164	572.00
IUUC-Eca-033542	Equus caballus	80.14	0.00e+00	914.00
IUUC-Fca-035490	Felis catus	77.35	0.00e+00	891.00
IUUC-Fal-036999	Ficedula albicollis	88.28	0.00e+00	1021.00
IUUC-Gmo-039532	Gadus morhua	93.66	0.00e+00	1050.00
IUUC-Gga-040215	Gallus gallus	74.24	0.00e+00	1078.00
IUUC-Gac-041582	Gasterosteus aculeatus	95.77	0.00e+00	1093.00
IUUC-Ggo-045074	Gorilla gorilla	69.80	0.00e+00	1013.00
IUUC-Hsa-046486	Homo sapiens	68.98	0.00e+00	977.00
IUUC-Itr-048921	Ictidomys tridecemlineatus	66.27	0.00e+00	924.00
IUUC-Lch-050265	Latimeria chalumnae	87.87	0.00e+00	1034.00
IUUC-Loc-052015	Lepisosteus oculatus	78.50	0.00e+00	1118.00
IUUC-Laf-053627	Loxodonta africana	81.37	0.00e+00	949.00
IUUC-Mcc-055418	Macaca mulatta	69.54	0.00e+00	1013.00
IUUC-Mga-059582	Meleagris gallopavo	74.54	0.00e+00	1042.00
IUUC-Mmr-061648	Microcebus murinus	82.27	0.00e+00	950.00
IUUC-Mdo-062785	Monodelphis domestica	85.59	0.00e+00	977.00
IUUC-Mmu-063334	Mus musculus	66.67	0.00e+00	927.00
IUUC-Mlu-067981	Myotis lucifugus	68.16	0.00e+00	979.00
IUUC-Ncr-068856	Neurospora crassa	40.74	7.00e-05	41.20
IUUC-Nle-070033	Nomascus leucogenys	68.90	0.00e+00	975.00
IUUC-Ont-071932	Oreochromis niloticus	83.77	0.00e+00	1188.00
IUUC-Ocu-074469	Oryctolagus cuniculus	66.40	0.00e+00	925.00
IUUC-Olo-080536	Oryza longistaminata	32.54	5.00e-35	143.00
IUUC-Ola-087436	Oryzias latipes	95.26	0.00e+00	1091.00
IUUC-Oar-089952	Ovis aries	68.19	0.00e+00	987.00
IUUC-Pan-091798	Papio anubis	69.67	0.00e+00	1013.00
IUUC-Psi-093728	Pelodiscus sinensis	86.64	0.00e+00	1017.00
IUUC-Pfo-096954	Poecilia formosa	81.05	0.00e+00	1142.00
IUUC-Pab-098461	Pongo abelii	69.37	0.00e+00	1000.00
IUUC-Pva-103042	Pteropus vampyrus	73.82	0.00e+00	904.00
IUUC-Sha-107322	Sarcophilus harrisii	83.60	0.00e+00	968.00
IUUC-Ssc-116001	Sus scrofa	81.42	0.00e+00	944.00
IUUC-Tgu-116994	Taeniopygia guttata	87.74	0.00e+00	1016.00
IUUC-Tni-120794	Tetraodon nigroviridis	83.40	0.00e+00	1143.00
IUUC-Tbe-128118	Tupaia belangeri	64.48	1.00e-173	603.00
IUUC-Ttr-129024	Tursiops truncatus	66.10	0.00e+00	924.00
IUUC-Vpa-130515	Vicugna pacos	77.70	0.00e+00	900.00
IUUC-Xtr-132358	Xenopus tropicalis	72.40	0.00e+00	1039.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence