iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005029

UUCD1 version

UUC-AnC-00186

Ensembl Protein ID

ENSACAP00000006987.3

UniProt Accession

H9GCC0; H9GCC0_ANOCA

Protein Name

Uncharacterized protein

Gene Name

TRAF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007135.3	ENSACAT00000007138.3	ENSACAP00000006987.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	58.47	2.00e-146	516.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MASAAAASAN VTPPGSLDED QVGFPKEILG TELEGKYLCS ECGNILRRPF QAQCGHRYCA 60
SCLQRLISSG PQKCGACIQE GIYEDGVSIL ETGSAFPDNA ARREVESLPA ICANEGCAWK 120

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Nucleotide Sequence
(Fasta)

GGTCGATGTT GTGGCACACA TGGCCTCCGC CGCCGCCGCC TCCGCCAACG TGACGCCACC 60
GGGGTCCCTG GACGAGGACC AGGTCGGGTT CCCGAAGGAG ATCCTGGGCA CGGAGCTAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	55.26	6.00e-143	500.00
IUUC-Apl-004202	Anas platyrhynchos	54.03	1.00e-139	489.00
IUUC-Bta-013180	Bos taurus	54.85	2.00e-139	488.00
IUUC-Cja-019813	Callithrix jacchus	58.47	9.00e-149	520.00
IUUC-Cfa-021205	Canis familiaris	57.77	6.00e-140	490.00
IUUC-Cpo-021346	Cavia porcellus	58.28	5.00e-146	510.00
IUUC-Csa-023809	Chlorocebus sabaeus	57.64	2.00e-123	435.00
IUUC-Dre-027669	Danio rerio	46.31	3.00e-113	401.00
IUUC-Dno-029458	Dasypus novemcinctus	55.88	3.00e-140	491.00
IUUC-Dor-030338	Dipodomys ordii	54.67	8.00e-127	446.00
IUUC-Eca-034401	Equus caballus	57.51	2.00e-145	509.00
IUUC-Eeu-034668	Erinaceus europaeus	73.17	3.00e-52	199.00
IUUC-Fca-036057	Felis catus	55.88	8.00e-144	503.00
IUUC-Fal-037560	Ficedula albicollis	54.67	3.00e-126	444.00
IUUC-Gmo-038964	Gadus morhua	50.23	3.00e-128	451.00
IUUC-Gga-040425	Gallus gallus	57.74	1.00e-150	526.00
IUUC-Gac-041908	Gasterosteus aculeatus	52.67	2.00e-127	449.00
IUUC-Ggo-044606	Gorilla gorilla	51.21	5.00e-121	427.00
IUUC-Hsa-046952	Homo sapiens	58.47	7.00e-148	516.00
IUUC-Lch-049571	Latimeria chalumnae	65.45	7.00e-90	324.00
IUUC-Lpe-051100	Leersia perrieri	34.92	7.00e-07	47.80
IUUC-Loc-051973	Lepisosteus oculatus	51.05	3.00e-116	412.00
IUUC-Laf-053815	Loxodonta africana	55.50	2.00e-140	491.00
IUUC-Mcc-054888	Macaca mulatta	59.16	4.00e-149	521.00
IUUC-Mga-059819	Meleagris gallopavo	57.34	2.00e-142	498.00
IUUC-Mdo-062570	Monodelphis domestica	58.39	5.00e-148	517.00
IUUC-Mmu-063133	Mus musculus	55.61	5.00e-140	491.00
IUUC-Mpu-065802	Mustela putorius furo	56.50	2.00e-144	505.00
IUUC-Nle-070155	Nomascus leucogenys	58.24	3.00e-148	518.00
IUUC-Opr-070856	Ochotona princeps	48.07	3.00e-56	212.00
IUUC-Ont-071930	Oreochromis niloticus	53.24	3.00e-137	481.00
IUUC-Ola-087397	Oryzias latipes	44.54	1.00e-101	363.00
IUUC-Oga-088109	Otolemur garnettii	57.54	2.00e-146	512.00
IUUC-Oar-090310	Ovis aries	64.84	2.00e-86	313.00
IUUC-Ptr-090643	Pan troglodytes	58.24	1.00e-147	515.00
IUUC-Pan-091933	Papio anubis	59.16	2.00e-149	521.00
IUUC-Psi-093681	Pelodiscus sinensis	55.91	4.00e-149	521.00
IUUC-Pfo-096148	Poecilia formosa	44.54	4.00e-102	365.00
IUUC-Pab-098631	Pongo abelii	58.24	6.00e-148	517.00
IUUC-Pca-100582	Procavia capensis	64.38	1.00e-55	210.00
IUUC-Pva-102396	Pteropus vampyrus	64.84	4.00e-85	308.00
IUUC-Rno-106120	Rattus norvegicus	55.06	9.00e-137	479.00
IUUC-Sha-106493	Sarcophilus harrisii	59.54	7.00e-150	523.00
IUUC-Sly-111800	Solanum lycopersicum	25.93	2.00e-05	45.40
IUUC-Ssc-115843	Sus scrofa	53.98	2.00e-140	492.00
IUUC-Tgu-117144	Taeniopygia guttata	51.71	2.00e-116	412.00
IUUC-Tru-117853	Takifugu rubripes	60.73	3.00e-84	305.00
IUUC-Tni-120256	Tetraodon nigroviridis	54.29	1.00e-138	486.00
IUUC-Ttr-129246	Tursiops truncatus	55.99	3.00e-139	488.00
IUUC-Xtr-132279	Xenopus tropicalis	47.07	5.00e-109	387.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence