iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013180

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02032446

Gene Name

TRAF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000010497.5	ENSBTAT00000013869.5	ENSBTAP00000013869.5

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	85.94	0.00e+00	891.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Protein Sequence
(Fasta)

AWAWWAAALM AAASVTPPGS LDLLQPGFSK TLLGTKLEDK YLCSACKNVL RRPFQAQCGH 60
RYCSFCLSSI LSSGPQSCAA CVHEGIYEEG VSILESSSAF PDNAARREVE SLPAVCPSEG 120

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Nucleotide Sequence
(Fasta)

GCGGCACCCG CAGCGGCTGG CTGGCAGGCA GTTCCGGGCG CGAGGCGACC GTTGGTGAGT 60
CCTGACGTCG GGGTCGGGGT CGCGGTGGGG TCGGGGGTCG GGGGTCGGGG TCTAGGGGCG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	87.09	0.00e+00	902.00
IUUC-Apl-004202	Anas platyrhynchos	71.27	0.00e+00	794.00
IUUC-Aca-005029	Anolis carolinensis	55.18	8.00e-140	489.00
IUUC-Ame-011841	Astyanax mexicanus	57.95	0.00e+00	674.00
IUUC-Cja-019813	Callithrix jacchus	84.99	0.00e+00	897.00
IUUC-Cfa-021205	Canis familiaris	87.50	0.00e+00	882.00
IUUC-Cpo-021346	Cavia porcellus	84.57	0.00e+00	887.00
IUUC-Csa-023809	Chlorocebus sabaeus	84.38	0.00e+00	786.00
IUUC-Dre-027669	Danio rerio	57.54	2.00e-174	605.00
IUUC-Dno-029458	Dasypus novemcinctus	82.39	0.00e+00	855.00
IUUC-Dor-030338	Dipodomys ordii	82.85	0.00e+00	810.00
IUUC-Eca-034401	Equus caballus	88.67	0.00e+00	931.00
IUUC-Eeu-034668	Erinaceus europaeus	94.08	2.00e-83	302.00
IUUC-Fca-036057	Felis catus	87.48	0.00e+00	911.00
IUUC-Fal-037560	Ficedula albicollis	69.79	0.00e+00	699.00
IUUC-Gmo-038964	Gadus morhua	60.16	0.00e+00	647.00
IUUC-Gga-040425	Gallus gallus	72.55	0.00e+00	792.00
IUUC-Gac-041908	Gasterosteus aculeatus	61.17	0.00e+00	652.00
IUUC-Ggo-044606	Gorilla gorilla	79.49	0.00e+00	809.00
IUUC-Hsa-046952	Homo sapiens	85.94	0.00e+00	896.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	71.35	0.00e+00	727.00
IUUC-Lch-049571	Latimeria chalumnae	54.33	0.00e+00	634.00
IUUC-Loc-051973	Lepisosteus oculatus	61.31	6.00e-178	617.00
IUUC-Laf-053815	Loxodonta africana	81.91	0.00e+00	819.00
IUUC-Mcc-054888	Macaca mulatta	86.13	0.00e+00	894.00
IUUC-Meu-056547	Macropus eugenii	68.43	2.00e-179	621.00
IUUC-Mga-059819	Meleagris gallopavo	71.29	0.00e+00	757.00
IUUC-Mdo-062570	Monodelphis domestica	78.43	0.00e+00	822.00
IUUC-Mmu-063133	Mus musculus	82.65	0.00e+00	848.00
IUUC-Mpu-065802	Mustela putorius furo	87.89	0.00e+00	905.00
IUUC-Nle-070155	Nomascus leucogenys	85.38	0.00e+00	902.00
IUUC-Opr-070856	Ochotona princeps	78.46	8.00e-105	374.00
IUUC-Ont-071930	Oreochromis niloticus	61.97	0.00e+00	687.00
IUUC-Ola-087397	Oryzias latipes	60.64	0.00e+00	669.00
IUUC-Oga-088109	Otolemur garnettii	84.80	0.00e+00	899.00
IUUC-Oar-090310	Ovis aries	85.55	0.00e+00	855.00
IUUC-Ptr-090643	Pan troglodytes	86.33	0.00e+00	900.00
IUUC-Pan-091933	Papio anubis	85.58	0.00e+00	896.00
IUUC-Psi-093681	Pelodiscus sinensis	72.58	0.00e+00	763.00
IUUC-Pfo-096148	Poecilia formosa	60.08	0.00e+00	672.00
IUUC-Pab-098631	Pongo abelii	86.33	0.00e+00	901.00
IUUC-Pca-100582	Procavia capensis	66.38	2.00e-81	296.00
IUUC-Pva-102396	Pteropus vampyrus	73.44	0.00e+00	729.00
IUUC-Rno-106120	Rattus norvegicus	78.91	0.00e+00	830.00
IUUC-Sha-106493	Sarcophilus harrisii	78.43	0.00e+00	842.00
IUUC-Sar-113570	Sorex araneus	93.37	2.00e-99	355.00
IUUC-Ssc-115843	Sus scrofa	87.98	0.00e+00	909.00
IUUC-Tgu-117144	Taeniopygia guttata	66.54	0.00e+00	672.00
IUUC-Tru-117853	Takifugu rubripes	60.80	0.00e+00	669.00
IUUC-Tni-120256	Tetraodon nigroviridis	63.09	0.00e+00	696.00
IUUC-Tbe-127943	Tupaia belangeri	62.66	6.00e-95	340.00
IUUC-Ttr-129246	Tursiops truncatus	90.04	0.00e+00	904.00
IUUC-Xtr-132279	Xenopus tropicalis	57.23	1.00e-167	583.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence