iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044987

UUCD1 version

UUC-GoG-00621

Ensembl Protein ID

ENSGGOP00000015500.2

UniProt Accession

G3RIJ4; G3RIJ4_GORGO

Protein Name

Uncharacterized protein

Gene Name

TRIM27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000015891.2	ENSGGOT00000015945.2	ENSGGOP00000015500.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	90.25	0.00e+00	875.00	IUUC-Hsa-046029
E3 activity/RING/RING	89.10	0.00e+00	866.00	IUUC-Mmu-064242

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

PLGEARCLRS PAPIQSQLGA QAQRAARPLQ AFGARARLGY GPGRRRPPSA RCLSGTANRR 60
ERRRVGLRAE LGAGAHARAP PQAGAMASGS VAECLQQETT CPVCLQYFAE PMMLDCGHNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCTTGGGG AGGCCAGGTG TTTGCGCTCC CCAGCACCTA TACAAAGCCA GCTTTCTTTT 60
TTTCGTTTCT TTTTTTTTTT TTTTTTTTGA GACAGAGTCT CCCTCTGTCC CGNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR020457--Znf_B-box_chordata
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01406--BBOXZNFINGER
PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0030904--C:retromer complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0034314--P:Arp2/3 complex-mediated actin nucleation
GO:0045087--P:innate immune response
GO:0072643--P:interferon-gamma secretion
GO:0002820--P:negative regulation of adaptive immune response
GO:0090281--P:negative regulation of calcium ion import
GO:0045814--P:negative regulation of gene expression, epigenetic
GO:1900041--P:negative regulation of interleukin-2 secretion
GO:0006469--P:negative regulation of protein kinase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032720--P:negative regulation of tumor necrosis factor production
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0051127--P:positive regulation of actin nucleation
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070534--P:protein K63-linked ubiquitination
GO:0070206--P:protein trimerization
GO:0042147--P:retrograde transport, endosome to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001890	Ailuropoda melanoleuca	88.95	0.00e+00	875.00
IUUC-Apl-003609	Anas platyrhynchos	39.26	4.00e-90	325.00
IUUC-Bta-013520	Bos taurus	89.87	0.00e+00	887.00
IUUC-Cja-019557	Callithrix jacchus	87.95	0.00e+00	868.00
IUUC-Cfa-020583	Canis familiaris	88.62	0.00e+00	826.00
IUUC-Cpo-021738	Cavia porcellus	81.07	0.00e+00	781.00
IUUC-Csa-023502	Chlorocebus sabaeus	90.44	0.00e+00	892.00
IUUC-Cho-024563	Choloepus hoffmanni	82.48	6.00e-150	523.00
IUUC-Dno-029747	Dasypus novemcinctus	86.81	0.00e+00	812.00
IUUC-Dor-030243	Dipodomys ordii	87.76	0.00e+00	850.00
IUUC-Ete-032749	Echinops telfairi	74.64	0.00e+00	698.00
IUUC-Eca-034246	Equus caballus	86.46	7.00e-171	593.00
IUUC-Eeu-034481	Erinaceus europaeus	79.16	0.00e+00	768.00
IUUC-Fca-036152	Felis catus	85.68	1.00e-169	588.00
IUUC-Gmo-038505	Gadus morhua	33.53	6.00e-70	258.00
IUUC-Gac-041323	Gasterosteus aculeatus	32.17	3.00e-68	252.00
IUUC-Hsa-046029	Homo sapiens	90.44	0.00e+00	892.00
IUUC-Itr-048438	Ictidomys tridecemlineatus	89.87	0.00e+00	863.00
IUUC-Laf-054488	Loxodonta africana	89.71	0.00e+00	891.00
IUUC-Mcc-055352	Macaca mulatta	90.44	0.00e+00	892.00
IUUC-Mmr-060883	Microcebus murinus	90.06	0.00e+00	887.00
IUUC-Mmu-064242	Mus musculus	89.29	0.00e+00	882.00
IUUC-Mpu-065958	Mustela putorius furo	89.35	0.00e+00	887.00
IUUC-Mlu-068005	Myotis lucifugus	74.21	7.00e-160	556.00
IUUC-Nle-069710	Nomascus leucogenys	85.99	5.00e-157	546.00
IUUC-Opr-071200	Ochotona princeps	89.48	0.00e+00	878.00
IUUC-Ocu-074081	Oryctolagus cuniculus	87.31	0.00e+00	749.00
IUUC-Ola-087166	Oryzias latipes	33.04	9.00e-71	261.00
IUUC-Oga-088784	Otolemur garnettii	90.06	0.00e+00	889.00
IUUC-Oar-089433	Ovis aries	89.87	0.00e+00	887.00
IUUC-Ptr-090595	Pan troglodytes	90.44	0.00e+00	892.00
IUUC-Pan-092027	Papio anubis	90.44	0.00e+00	892.00
IUUC-Pab-098331	Pongo abelii	90.44	0.00e+00	892.00
IUUC-Pca-101091	Procavia capensis	90.06	0.00e+00	887.00
IUUC-Pva-103141	Pteropus vampyrus	86.80	9.00e-178	615.00
IUUC-Rno-105507	Rattus norvegicus	88.91	0.00e+00	877.00
IUUC-Sar-113713	Sorex araneus	80.84	0.00e+00	799.00
IUUC-Ssc-115594	Sus scrofa	89.15	0.00e+00	890.00
IUUC-Tsy-119235	Tarsius syrichta	86.55	1.00e-173	602.00
IUUC-Tni-120295	Tetraodon nigroviridis	36.62	1.00e-72	267.00
IUUC-Tbe-127796	Tupaia belangeri	77.74	1.00e-122	433.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence