iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090595

UUCD1 version

UUC-PaT-00572

Ensembl Protein ID

ENSPTRP00000030492.4

UniProt Accession

H2QSK5; H2QSK5_PANTR

Genbank Protein ID

JAA04095.1; JAA13874.1; JAA30606.1; JAA33243.1

Protein Name

Tripartite motif containing 27

Genbank Nucleotide ID

AACZ03050205; GABF01008271; GABD01002494; GABE01011496

Gene Name

TRIM27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000017883.5	ENSPTRT00000033008.4	ENSPTRP00000030492.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	100.00	0.00e+00	990.00	IUUC-Hsa-046029
E3 activity/RING/RING	98.83	0.00e+00	981.00	IUUC-Mmu-064242

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MASGSVAECL QQETTCPVCL QYFAEPMMLD CGHNICCACL ARCWGTAETN VSCPQCRETF 60
PQRHMRPNRH LANVTQLVKQ LRTERPSGPG GEMGVCEKHR EPLKLYCEED QMPICVVCDR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTTTACGC GGCCGCCGGG ATCCGCTAGG ACGCGGCCAC GTTGTCTTGC GCGGTTTGCC 60
CGCCTGGCCC TGGGACTCTG ACCCTCGGCT ACCCTTTGCT GCCCCACTAG CGTGGCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR020457--Znf_B-box_chordata
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01406--BBOXZNFINGER
PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0030904--C:retromer complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0034314--P:Arp2/3 complex-mediated actin nucleation
GO:0045087--P:innate immune response
GO:0072643--P:interferon-gamma secretion
GO:0002820--P:negative regulation of adaptive immune response
GO:0090281--P:negative regulation of calcium ion import
GO:0045814--P:negative regulation of gene expression, epigenetic
GO:1900041--P:negative regulation of interleukin-2 secretion
GO:0006469--P:negative regulation of protein kinase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032720--P:negative regulation of tumor necrosis factor production
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0051127--P:positive regulation of actin nucleation
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070534--P:protein K63-linked ubiquitination
GO:0070206--P:protein trimerization
GO:0042147--P:retrograde transport, endosome to Golgi

KEGG

ptr:739369

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001890	Ailuropoda melanoleuca	98.62	0.00e+00	971.00
IUUC-Apl-003609	Anas platyrhynchos	40.29	5.00e-97	347.00
IUUC-Ame-011639	Astyanax mexicanus	34.42	2.00e-69	256.00
IUUC-Bta-013520	Bos taurus	99.42	0.00e+00	985.00
IUUC-Cja-019557	Callithrix jacchus	97.47	0.00e+00	967.00
IUUC-Cfa-020583	Canis familiaris	98.57	0.00e+00	924.00
IUUC-Cpo-021738	Cavia porcellus	90.25	0.00e+00	879.00
IUUC-Csa-023502	Chlorocebus sabaeus	100.00	0.00e+00	990.00
IUUC-Cho-024563	Choloepus hoffmanni	95.84	3.00e-179	621.00
IUUC-Dno-029747	Dasypus novemcinctus	96.59	0.00e+00	910.00
IUUC-Dor-030243	Dipodomys ordii	96.88	0.00e+00	935.00
IUUC-Ete-032749	Echinops telfairi	84.55	0.00e+00	796.00
IUUC-Eca-034246	Equus caballus	99.47	0.00e+00	694.00
IUUC-Eeu-034481	Erinaceus europaeus	88.50	0.00e+00	867.00
IUUC-Fca-036152	Felis catus	98.66	0.00e+00	688.00
IUUC-Gac-042288	Gasterosteus aculeatus	37.58	2.00e-75	276.00
IUUC-Ggo-044987	Gorilla gorilla	90.25	0.00e+00	875.00
IUUC-Hsa-046029	Homo sapiens	100.00	0.00e+00	990.00
IUUC-Itr-048438	Ictidomys tridecemlineatus	99.42	0.00e+00	960.00
IUUC-Laf-054488	Loxodonta africana	99.61	0.00e+00	980.00
IUUC-Mcc-055352	Macaca mulatta	100.00	0.00e+00	990.00
IUUC-Mmr-060883	Microcebus murinus	99.61	0.00e+00	985.00
IUUC-Mmu-064242	Mus musculus	98.83	0.00e+00	981.00
IUUC-Mpu-065958	Mustela putorius furo	99.03	0.00e+00	982.00
IUUC-Mlu-068005	Myotis lucifugus	85.54	0.00e+00	654.00
IUUC-Nle-069710	Nomascus leucogenys	99.72	0.00e+00	644.00
IUUC-Opr-071200	Ochotona princeps	99.03	0.00e+00	976.00
IUUC-Ocu-074081	Oryctolagus cuniculus	98.02	0.00e+00	846.00
IUUC-Ola-087166	Oryzias latipes	33.58	4.00e-70	258.00
IUUC-Oga-088784	Otolemur garnettii	99.61	0.00e+00	986.00
IUUC-Oar-089433	Ovis aries	99.42	0.00e+00	985.00
IUUC-Pan-092027	Papio anubis	100.00	0.00e+00	990.00
IUUC-Psi-093179	Pelodiscus sinensis	47.36	3.00e-116	411.00
IUUC-Pfo-096858	Poecilia formosa	33.77	7.00e-69	254.00
IUUC-Pab-098331	Pongo abelii	100.00	0.00e+00	990.00
IUUC-Pca-101091	Procavia capensis	99.61	0.00e+00	986.00
IUUC-Pva-103141	Pteropus vampyrus	99.48	0.00e+00	715.00
IUUC-Rno-105507	Rattus norvegicus	98.44	0.00e+00	976.00
IUUC-Sar-113713	Sorex araneus	90.23	0.00e+00	897.00
IUUC-Ssc-115594	Sus scrofa	99.41	0.00e+00	983.00
IUUC-Tru-118630	Takifugu rubripes	34.27	7.00e-72	264.00
IUUC-Tsy-119235	Tarsius syrichta	99.22	0.00e+00	702.00
IUUC-Tni-120295	Tetraodon nigroviridis	37.37	6.00e-75	274.00
IUUC-Tbe-127796	Tupaia belangeri	88.64	5.00e-139	487.00
IUUC-Ttr-128738	Tursiops truncatus	99.46	0.00e+00	692.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence