iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054270

UUCD1 version

UUC-LoA-00516

Ensembl Protein ID

ENSLAFP00000012378.3

UniProt Accession

G3TDU7; G3TDU7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

NSMCE2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000014786.3	ENSLAFT00000014784.3	ENSLAFP00000012378.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.30e-09	37.5	163	239

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlp.sGitydrssIekwlasggk.....tcPvtrqpl...teedlvPnltlrrliqawcee 71
             f+CpI+   M+ Pv  + +G+ty+ ++I + ++s++k      cP+ + +    + +dlv   +lrr i+++ ++
   Q: 163  TNFICPITQLEMKKPVKNKvCGHTYEEEAIVRMIESKHKrkkkaCCPKIGCSHtdvRMSDLVQDEALRRAIESHNKK 239
           57********************************9999999999888865544223789************998665 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MPGRSNSGSA GFISFSGVES ALCSLKSFQS CIGSGMDAAS SVALDLVETQ TEVSSEYSME 60
KAMVEFAVMD RELNHYVKAV QSVINRVKEE RPEKIPDLKL LVQKNFVALQ SKNSDADFQH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGGGGC GTTCAAATTC AGGGTCTGCT GGCTTCATCT CCTTCAGCGG TGTCGAATCT 60
GCTCTCTGCT CCTTAAAAAG CTTCCAGTCC TGCATCGGCT CTGGAATGGA CGCAGCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR026846--Nse2(Mms21)
IPR003613--Ubox_domain
IPR004181--Znf_MIZ
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51044--ZF_SP_RING

Pfam

PF11789--zf-Nse

SMART

SM00504--Ubox

Gene Ontology

GO:0000781--C:chromosome, telomeric region
GO:0016605--C:PML body
GO:0030915--C:Smc5-Smc6 complex
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0000724--P:double-strand break repair via homologous recombination
GO:0034184--P:positive regulation of maintenance of mitotic sister chromatid cohesion
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001627	Ailuropoda melanoleuca	84.00	5.00e-101	360.00
IUUC-Atr-002438	Amborella trichopoda	29.59	3.00e-06	45.40
IUUC-Apl-004091	Anas platyrhynchos	67.37	1.00e-31	127.00
IUUC-Aca-004433	Anolis carolinensis	48.93	6.00e-65	240.00
IUUC-Aly-006133	Arabidopsis lyrata	26.94	3.00e-08	52.00
IUUC-Ath-007424	Arabidopsis thaliana	28.50	3.00e-10	58.90
IUUC-Ago-007852	Ashbya gossypii	29.73	1.00e-06	46.20
IUUC-Acl-008011	Aspergillus clavatus	32.56	4.00e-03	36.20
IUUC-Afu-008893	Aspergillus fumigatus	32.56	1.00e-03	37.70
IUUC-Ani-009414	Aspergillus nidulans	30.61	5.00e-04	39.30
IUUC-Ate-010326	Aspergillus terreus	34.88	7.00e-03	36.60
IUUC-Ame-010902	Astyanax mexicanus	42.79	5.00e-46	177.00
IUUC-Bgr-012088	Blumeria graminis	25.81	9.00e-06	44.30
IUUC-Bta-013397	Bos taurus	85.47	1.00e-66	244.00
IUUC-Bci-013738	Botrytis cinerea	26.42	7.00e-06	45.10
IUUC-Bol-015454	Brassica oleracea	24.87	1.00e-07	49.70
IUUC-Cel-018588	Caenorhabditis elegans	32.26	1.40e-02	32.70
IUUC-Cja-019246	Callithrix jacchus	87.72	1.00e-106	379.00
IUUC-Cpo-021670	Cavia porcellus	86.03	2.00e-95	341.00
IUUC-Csa-023982	Chlorocebus sabaeus	82.02	1.00e-97	348.00
IUUC-Cin-025127	Ciona intestinalis	23.89	2.00e-16	79.00
IUUC-Cgl-026430	Colletotrichum gloeosporioides	33.90	3.00e-07	49.30
IUUC-Cne-026806	Cryptococcus neoformans	36.59	4.00e-08	52.00
IUUC-Cme-027175	Cyanidioschyzon merolae	29.58	4.00e-05	42.00
IUUC-Dre-028325	Danio rerio	37.67	1.00e-33	135.00
IUUC-Dno-029735	Dasypus novemcinctus	86.84	2.00e-117	414.00
IUUC-Dor-030454	Dipodomys ordii	69.06	1.00e-73	269.00
IUUC-Dme-031971	Drosophila melanogaster	25.00	3.00e-07	48.50
IUUC-Ete-032838	Echinops telfairi	63.87	2.00e-50	191.00
IUUC-Eca-034371	Equus caballus	81.38	5.00e-113	400.00
IUUC-Eeu-035258	Erinaceus europaeus	83.33	5.00e-80	290.00
IUUC-Fca-035576	Felis catus	84.89	9.00e-103	365.00
IUUC-Fal-037038	Ficedula albicollis	55.95	4.00e-73	267.00
IUUC-Fox-037843	Fusarium oxysporum	32.86	4.00e-06	45.40
IUUC-Fso-038272	Fusarium solani	31.25	7.00e-06	44.70
IUUC-Ggr-040059	Gaeumannomyces graminis	28.57	3.00e-06	46.20
IUUC-Gga-040737	Gallus gallus	45.56	1.00e-57	216.00
IUUC-Gac-042591	Gasterosteus aculeatus	42.49	2.00e-44	172.00
IUUC-Gma-043177	Glycine max	24.35	4.00e-07	48.50
IUUC-Ggo-045206	Gorilla gorilla	82.89	6.00e-102	363.00
IUUC-Hsa-046704	Homo sapiens	83.33	9.00e-103	365.00
IUUC-Itr-048972	Ictidomys tridecemlineatus	86.05	5.00e-45	172.00
IUUC-Kpa-049181	Komagataella pastoris	29.79	3.00e-10	58.50
IUUC-Loc-052687	Lepisosteus oculatus	40.95	2.00e-42	165.00
IUUC-Lma-053255	Leptosphaeria maculans	31.34	2.00e-05	44.30
IUUC-Mcc-054757	Macaca mulatta	81.82	2.00e-77	281.00
IUUC-Mor-057028	Magnaporthe oryzae	30.00	2.00e-06	46.60
IUUC-Mpo-057462	Magnaporthe poae	28.57	3.00e-07	49.70
IUUC-Mtr-058011	Medicago truncatula	27.27	2.00e-10	59.30
IUUC-Mga-059215	Meleagris gallopavo	69.51	8.00e-33	131.00
IUUC-Mvi-060511	Microbotryum violaceum	31.17	1.00e-06	47.40
IUUC-Mmr-061584	Microcebus murinus	83.81	2.00e-103	368.00
IUUC-Mdo-061863	Monodelphis domestica	55.23	1.00e-74	272.00
IUUC-Mmu-064413	Mus musculus	83.76	5.00e-107	380.00
IUUC-Mac-065639	Musa acuminata	28.71	3.00e-05	42.00
IUUC-Mpu-066092	Mustela putorius furo	71.54	1.00e-99	355.00
IUUC-Mlu-068198	Myotis lucifugus	86.67	3.00e-115	407.00
IUUC-Nfi-068508	Neosartorya fischeri	27.94	1.00e-03	37.70
IUUC-Ncr-068773	Neurospora crassa	29.06	6.00e-06	45.40
IUUC-Nle-070109	Nomascus leucogenys	84.21	3.00e-104	370.00
IUUC-Opr-070540	Ochotona princeps	59.91	2.00e-62	232.00
IUUC-Ont-071575	Oreochromis niloticus	42.74	2.00e-46	178.00
IUUC-Oan-072777	Ornithorhynchus anatinus	78.57	4.00e-24	102.00
IUUC-Ocu-074730	Oryctolagus cuniculus	87.56	2.00e-106	377.00
IUUC-Oga-087925	Otolemur garnettii	85.53	4.00e-97	347.00
IUUC-Oar-090138	Ovis aries	76.47	2.00e-92	331.00
IUUC-Ptr-091582	Pan troglodytes	83.33	9.00e-103	365.00
IUUC-Pan-092890	Papio anubis	82.02	1.00e-97	348.00
IUUC-Psi-093714	Pelodiscus sinensis	56.25	2.00e-74	271.00
IUUC-Pma-094198	Petromyzon marinus	29.20	2.00e-18	84.30
IUUC-Pno-094931	Phaeosphaeria nodorum	32.47	5.00e-05	42.40
IUUC-Pab-098005	Pongo abelii	82.89	1.00e-102	365.00
IUUC-Pop-099559	Populus trichocarpa	25.13	1.00e-07	50.10
IUUC-Pca-100368	Procavia capensis	70.18	1.00e-67	249.00
IUUC-Ppe-101873	Prunus persica	27.32	4.00e-11	61.60
IUUC-Pva-102951	Pteropus vampyrus	85.97	3.00e-107	380.00
IUUC-Pte-104390	Pyrenophora teres	38.57	1.00e-05	43.90
IUUC-Rno-105346	Rattus norvegicus	84.21	4.00e-113	400.00
IUUC-Sha-107586	Sarcophilus harrisii	70.54	1.00e-42	164.00
IUUC-Sja-107983	Schizosaccharomyces japonicus	32.98	6.00e-10	57.80
IUUC-Spo-108327	Schizosaccharomyces pombe	31.87	8.00e-05	40.40
IUUC-Ssl-108555	Sclerotinia sclerotiorum	30.93	2.00e-06	46.60
IUUC-Sit-109919	Setaria italica	27.44	5.00e-06	45.10
IUUC-Sly-111667	Solanum lycopersicum	30.30	7.00e-05	40.80
IUUC-Stu-112211	Solanum tuberosum	33.33	1.00e-05	43.10
IUUC-Sar-113609	Sorex araneus	83.33	3.00e-98	350.00
IUUC-Sre-115187	Sporisorium reilianum	30.68	1.00e-05	43.90
IUUC-Tgu-116472	Taeniopygia guttata	54.63	2.00e-70	258.00
IUUC-Tru-117771	Takifugu rubripes	41.25	9.00e-42	163.00
IUUC-Tni-119821	Tetraodon nigroviridis	39.09	6.00e-44	170.00
IUUC-Tca-121272	Theobroma cacao	27.59	7.00e-06	44.30
IUUC-Tre-122049	Trichoderma reesei	32.93	8.00e-09	54.70
IUUC-Tvi-122642	Trichoderma virens	30.49	2.00e-07	49.70
IUUC-Tme-126988	Tuber melanosporum	31.00	3.00e-07	49.30
IUUC-Tbe-127676	Tupaia belangeri	86.29	2.00e-89	320.00
IUUC-Ttr-128602	Tursiops truncatus	82.23	1.00e-102	365.00
IUUC-Uma-129520	Ustilago maydis	28.57	3.00e-04	39.30
IUUC-Vpa-130510	Vicugna pacos	86.22	3.00e-104	370.00
IUUC-Vvi-131486	Vitis vinifera	31.28	3.00e-11	62.00
IUUC-Yli-134676	Yarrowia lipolytica	30.88	4.00e-05	42.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence