iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091437

UUCD1 version

UUC-PaT-00671

Ensembl Protein ID

ENSPTRP00000026924.3

UniProt Accession

H2QNS5; H2QNS5_PANTR

Genbank Protein ID

JAA02763.1; JAA02764.1; JAA02765.1; JAA14259.1; JAA14260.1; JAA14261.1; JAA29403.1; JAA29404.1; JAA39412.1; JAA39413.1

Protein Name

Guanine nucleotide binding protein (G protein), beta polypeptide 4

Genbank Nucleotide ID

AACZ03022739; GABC01008574; GABC01008573; GABF01007886; GABF01007885; GABF01007884; GABD01003697; GABD01003696; GABE01005327; GABE01005326

Gene Name

GNB4; GNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000015646.3	ENSPTRT00000029174.3	ENSPTRP00000026924.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.20e-39	130.3	224	258
UBD/Beta-Prp	4.90e-52	176.9	46	269

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH +++++++f ++   +++GsdD t++++Dlr +
   Q: 224  GHVSDINAVSFfPNgYAFATGSDDATCRLFDLRAD 258
           8*********99885679**************987 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
            + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   +h++   ++ v+++++ psg++++ G+ d++  +++l+t++    
   Q: 46   RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR 134
           446899*****************************************************************************987776 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
               l gh+g  +c ++ + ++ +v++s D+t+ lWd++t++  +t+tg h ++v sls++++++ +vsg++d + klwd++ g c ++
   Q: 135  vsrELPGHTGYLSCCRFLD-DSQIVTSSGDTTCALWDIETAQQTTTFTG-HSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQS 221
           6779*************99.67789***********************9.*************************************** PP
   S: 218  lnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           ++gh + ++ v f+pn+  +++gs+D + r++dlr ++ l  +++   ++
   Q: 222  FTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHD--NI 269
           **************************************99988874..44 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MSELEQLRQE AEQLRNQIQD ARKACNDATL VQITSNMDSV GRIQMRTRRT LRGHLAKIYA 60
MHWGYDSRLL VSASQDGKLI IWDSYTTNKM HAIPLRSSWV MTCAYAPSGN YVACGGLDNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGTCCCCGC CGGGCCCGCG CGCCTCGTGC CTCGCGCCTC GCGCCTCCAG CCACGTACCC 60
GCCCCGGCTC CGGCGCGCCG CGGAGTTGGC TGCTGGGAGG TGCGGGACTG GGTGTGGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0007165--P:signal transduction
GO:0021762--P:substantia nigra development

KEGG

ptr:460862

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000161	Aegilops tauschii	50.19	4.00e-74	271.00
IUUC-Aml-001727	Ailuropoda melanoleuca	99.69	0.00e+00	667.00
IUUC-Atr-002610	Amborella trichopoda	46.88	4.00e-83	301.00
IUUC-Apl-003923	Anas platyrhynchos	94.75	8.00e-176	608.00
IUUC-Aca-004754	Anolis carolinensis	94.74	3.00e-176	610.00
IUUC-Acl-008154	Aspergillus clavatus	66.47	6.00e-137	480.00
IUUC-Afl-008568	Aspergillus flavus	66.47	2.00e-138	485.00
IUUC-Afu-008789	Aspergillus fumigatus	66.47	5.00e-137	480.00
IUUC-Ani-009213	Aspergillus nidulans	65.88	2.00e-136	478.00
IUUC-Ang-009836	Aspergillus niger	66.18	5.00e-138	483.00
IUUC-Aor-010165	Aspergillus oryzae	66.47	2.00e-138	485.00
IUUC-Ate-010520	Aspergillus terreus	61.76	5.00e-110	390.00
IUUC-Ame-011092	Astyanax mexicanus	90.88	0.00e+00	650.00
IUUC-Bta-013200	Bos taurus	99.69	0.00e+00	665.00
IUUC-Cja-019845	Callithrix jacchus	99.69	0.00e+00	666.00
IUUC-Cfa-020395	Canis familiaris	99.69	0.00e+00	667.00
IUUC-Cpo-021376	Cavia porcellus	99.07	0.00e+00	665.00
IUUC-Csa-023295	Chlorocebus sabaeus	100.00	0.00e+00	667.00
IUUC-Cho-024766	Choloepus hoffmanni	99.38	0.00e+00	668.00
IUUC-Dno-029802	Dasypus novemcinctus	99.34	0.00e+00	627.00
IUUC-Dse-031388	Dothistroma septosporum	66.76	2.00e-137	481.00
IUUC-Dme-031748	Drosophila melanogaster	81.47	5.00e-173	599.00
IUUC-Ete-032710	Echinops telfairi	96.75	6.00e-180	622.00
IUUC-Eca-033628	Equus caballus	99.38	0.00e+00	664.00
IUUC-Eeu-034978	Erinaceus europaeus	97.44	9.00e-158	548.00
IUUC-Fal-037616	Ficedula albicollis	95.05	6.00e-177	612.00
IUUC-Gmo-039556	Gadus morhua	92.57	0.00e+00	625.00
IUUC-Gga-040249	Gallus gallus	95.05	6.00e-177	612.00
IUUC-Gac-041805	Gasterosteus aculeatus	91.64	0.00e+00	625.00
IUUC-Ggo-044954	Gorilla gorilla	99.69	0.00e+00	666.00
IUUC-Hsa-046105	Homo sapiens	100.00	0.00e+00	667.00
IUUC-Itr-048623	Ictidomys tridecemlineatus	100.00	0.00e+00	664.00
IUUC-Kpa-049192	Komagataella pastoris	38.89	1.00e-62	233.00
IUUC-Lch-049422	Latimeria chalumnae	91.76	0.00e+00	626.00
IUUC-Lpe-051040	Leersia perrieri	50.00	3.00e-85	308.00
IUUC-Loc-052939	Lepisosteus oculatus	91.47	0.00e+00	652.00
IUUC-Mcc-055787	Macaca mulatta	100.00	0.00e+00	667.00
IUUC-Mga-060050	Meleagris gallopavo	94.75	8.00e-176	608.00
IUUC-Mmr-060931	Microcebus murinus	100.00	0.00e+00	667.00
IUUC-Mdo-063055	Monodelphis domestica	94.43	3.00e-176	610.00
IUUC-Mmu-064368	Mus musculus	96.59	0.00e+00	650.00
IUUC-Mac-064871	Musa acuminata	45.40	6.00e-82	297.00
IUUC-Mpu-066358	Mustela putorius furo	99.69	0.00e+00	667.00
IUUC-Mlu-067328	Myotis lucifugus	98.76	0.00e+00	660.00
IUUC-Nfi-068332	Neosartorya fischeri	66.47	1.00e-136	479.00
IUUC-Nle-069612	Nomascus leucogenys	100.00	0.00e+00	667.00
IUUC-Ont-071287	Oreochromis niloticus	92.57	0.00e+00	625.00
IUUC-Oan-072913	Ornithorhynchus anatinus	95.36	5.00e-178	616.00
IUUC-Ocu-074126	Oryctolagus cuniculus	99.38	0.00e+00	670.00
IUUC-Oba-075818	Oryza barthii	48.31	4.00e-82	298.00
IUUC-Oni-082161	Oryza nivara	50.00	3.00e-85	308.00
IUUC-Ola-087297	Oryzias latipes	92.31	0.00e+00	628.00
IUUC-Oar-089360	Ovis aries	99.69	0.00e+00	665.00
IUUC-Pan-092195	Papio anubis	99.69	0.00e+00	666.00
IUUC-Psi-093718	Pelodiscus sinensis	95.05	6.00e-177	612.00
IUUC-Pno-095135	Phaeosphaeria nodorum	65.49	3.00e-135	474.00
IUUC-Pfo-096251	Poecilia formosa	92.26	4.00e-180	623.00
IUUC-Pop-099273	Populus trichocarpa	48.61	3.00e-85	308.00
IUUC-Pte-104053	Pyrenophora teres	65.49	2.00e-135	475.00
IUUC-Sce-106298	Saccharomyces cerevisiae	37.40	2.00e-68	253.00
IUUC-Sha-106534	Sarcophilus harrisii	94.43	1.00e-176	611.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	35.48	8.00e-60	223.00
IUUC-Spo-108352	Schizosaccharomyces pombe	41.69	1.00e-69	256.00
IUUC-Smo-108835	Selaginella moellendorffii	43.58	2.00e-74	272.00
IUUC-Sit-110441	Setaria italica	50.32	1.00e-85	309.00
IUUC-Sly-111784	Solanum lycopersicum	48.71	1.00e-81	296.00
IUUC-Stu-112400	Solanum tuberosum	48.71	9.00e-82	296.00
IUUC-Sar-113642	Sorex araneus	99.26	3.00e-161	560.00
IUUC-Tgu-117198	Taeniopygia guttata	95.05	6.00e-177	612.00
IUUC-Tru-118399	Takifugu rubripes	91.95	1.00e-180	624.00
IUUC-Tsy-119354	Tarsius syrichta	96.59	0.00e+00	649.00
IUUC-Tni-120495	Tetraodon nigroviridis	90.88	0.00e+00	643.00
IUUC-Tme-126886	Tuber melanosporum	67.96	1.00e-134	472.00
IUUC-Ttr-129243	Tursiops truncatus	100.00	0.00e+00	667.00
IUUC-Xtr-131924	Xenopus tropicalis	95.05	6.00e-177	613.00
IUUC-Xma-133743	Xiphophorus maculatus	92.06	0.00e+00	654.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence