iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052181

Ensembl Protein ID

ENSLOCP00000004893.1

UniProt Accession

W5M934; W5M934_LEPOC

Genbank Protein ID

ENSLOCP00000004893

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AHAT01024182

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000004045.1	ENSLOCT00000004900.1	ENSLOCP00000004893.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.00e-22	77.5	1761	1814

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedek.slveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           +C+vCg++++++k +l+eC+kCr+ +Hp+Cl+++  +++p+++k  wiC+kC ++
   Q: 1761 FCHVCGRQHQKTKqQLLECNKCRNSYHPECLGPN-HPTRPTKKKriWICTKCVRC 1814
           8*********9989********************.*******99********876 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MAHSCRWRFP ARPGGSSNAG SGRRAGRIRV TASLRTGSGP QPNASGLGPG FDAALQVSAA 60
IGNNLQKFRD VFGEASGSSS GEEETFLGFG THHENRRIHS SARSPTVKSR QERKPRGRPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTTATGTA ATGGTTGCTT GGTGAATACA CAGGTTCGGG GCCGCGCCCC CTCAGCACCC 60
TGATCTTAGG GCAAGCAGGC AGAGTGTAAA ATGGCGCACA GCTGTCGGTG GCGGTTCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR016569--MeTrfase_trithorax
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50014--BROMODOMAIN_2
PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0021782--P:glial cell development
GO:0048823--P:nucleate erythrocyte development
GO:0048339--P:paraxial mesoderm development
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002274	Ailuropoda melanoleuca	77.10	0.00e+00	1282.00
IUUC-Atr-002455	Amborella trichopoda	40.41	1.00e-39	158.00
IUUC-Apl-003478	Anas platyrhynchos	77.14	0.00e+00	1258.00
IUUC-Aca-005086	Anolis carolinensis	73.82	0.00e+00	1286.00
IUUC-Aly-006448	Arabidopsis lyrata	48.73	5.00e-40	160.00
IUUC-Ath-006690	Arabidopsis thaliana	36.96	3.00e-37	150.00
IUUC-Ame-011195	Astyanax mexicanus	54.31	0.00e+00	1860.00
IUUC-Bta-012974	Bos taurus	76.77	0.00e+00	1277.00
IUUC-Bdi-014882	Brachypodium distachyon	33.50	3.00e-26	113.00
IUUC-Bol-016540	Brassica oleracea	48.05	1.00e-37	152.00
IUUC-Bra-017404	Brassica rapa	34.01	1.00e-24	108.00
IUUC-Cja-019226	Callithrix jacchus	77.48	0.00e+00	1278.00
IUUC-Cfa-021049	Canis familiaris	76.44	0.00e+00	1281.00
IUUC-Cpo-021459	Cavia porcellus	76.64	0.00e+00	1258.00
IUUC-Cre-022891	Chlamydomonas reinhardtii	51.56	1.00e-38	156.00
IUUC-Csa-023434	Chlorocebus sabaeus	77.12	0.00e+00	1275.00
IUUC-Cho-024652	Choloepus hoffmanni	76.82	0.00e+00	1055.00
IUUC-Cin-025724	Ciona intestinalis	55.10	1.00e-95	345.00
IUUC-Csv-026268	Ciona savignyi	36.47	8.00e-130	458.00
IUUC-Cme-027224	Cyanidioschyzon merolae	36.71	1.00e-12	68.90
IUUC-Dre-028180	Danio rerio	59.27	0.00e+00	3106.00
IUUC-Dno-029068	Dasypus novemcinctus	48.31	0.00e+00	1130.00
IUUC-Dor-030550	Dipodomys ordii	69.28	0.00e+00	1042.00
IUUC-Dme-032023	Drosophila melanogaster	47.97	2.00e-90	329.00
IUUC-Ete-032834	Echinops telfairi	48.72	0.00e+00	1013.00
IUUC-Eca-033615	Equus caballus	76.50	0.00e+00	1267.00
IUUC-Eeu-035136	Erinaceus europaeus	66.08	0.00e+00	859.00
IUUC-Fal-037256	Ficedula albicollis	78.66	0.00e+00	1312.00
IUUC-Gmo-038641	Gadus morhua	73.99	0.00e+00	1179.00
IUUC-Gga-040828	Gallus gallus	77.14	0.00e+00	1285.00
IUUC-Gac-041452	Gasterosteus aculeatus	75.59	0.00e+00	1256.00
IUUC-Gma-043554	Glycine max	49.02	2.00e-38	154.00
IUUC-Ggo-045124	Gorilla gorilla	73.80	0.00e+00	1063.00
IUUC-Hsa-046143	Homo sapiens	77.00	0.00e+00	1275.00
IUUC-Hvu-047762	Hordeum vulgare	34.85	1.00e-18	87.80
IUUC-Itr-049024	Ictidomys tridecemlineatus	66.15	0.00e+00	1566.00
IUUC-Lch-049704	Latimeria chalumnae	75.96	0.00e+00	1244.00
IUUC-Lpe-051476	Leersia perrieri	30.88	1.00e-22	101.00
IUUC-Laf-053946	Loxodonta africana	76.50	0.00e+00	1268.00
IUUC-Mcc-055508	Macaca mulatta	76.73	0.00e+00	1269.00
IUUC-Mtr-058327	Medicago truncatula	49.67	1.00e-37	152.00
IUUC-Mga-059943	Meleagris gallopavo	77.58	0.00e+00	1273.00
IUUC-Mmr-061178	Microcebus murinus	76.98	0.00e+00	1278.00
IUUC-Mdo-063031	Monodelphis domestica	76.98	0.00e+00	1286.00
IUUC-Mmu-063650	Mus musculus	76.22	0.00e+00	1255.00
IUUC-Mpu-066495	Mustela putorius furo	76.98	0.00e+00	1271.00
IUUC-Mlu-068045	Myotis lucifugus	76.01	0.00e+00	1253.00
IUUC-Nle-069064	Nomascus leucogenys	76.73	0.00e+00	1271.00
IUUC-Opr-071043	Ochotona princeps	72.63	0.00e+00	1148.00
IUUC-Ont-072556	Oreochromis niloticus	65.38	0.00e+00	1248.00
IUUC-Oan-073324	Ornithorhynchus anatinus	71.55	0.00e+00	1162.00
IUUC-Ocu-074190	Oryctolagus cuniculus	77.31	0.00e+00	1270.00
IUUC-Oba-075647	Oryza barthii	49.36	4.00e-38	153.00
IUUC-Obr-076458	Oryza brachyantha	33.50	3.00e-26	113.00
IUUC-Ogl-077851	Oryza glaberrima	33.50	3.00e-25	110.00
IUUC-Ogu-078706	Oryza glumaepatula	32.67	5.00e-26	113.00
IUUC-Olo-080577	Oryza longistaminata	47.71	9.00e-36	145.00
IUUC-Ome-081214	Oryza meridionalis	49.36	4.00e-38	153.00
IUUC-Oni-083000	Oryza nivara	49.36	5.00e-38	153.00
IUUC-Opu-083842	Oryza punctata	49.36	4.00e-38	153.00
IUUC-Oru-084361	Oryza rufipogon	49.36	4.00e-38	153.00
IUUC-Ola-087176	Oryzias latipes	68.39	0.00e+00	1237.00
IUUC-Oga-088208	Otolemur garnettii	76.59	0.00e+00	1268.00
IUUC-Oar-090152	Ovis aries	76.50	0.00e+00	1274.00
IUUC-Ptr-091127	Pan troglodytes	77.00	0.00e+00	1274.00
IUUC-Pan-092679	Papio anubis	77.00	0.00e+00	1269.00
IUUC-Psi-094059	Pelodiscus sinensis	76.07	0.00e+00	1253.00
IUUC-Pma-094258	Petromyzon marinus	57.91	0.00e+00	640.00
IUUC-Pfo-096536	Poecilia formosa	73.69	0.00e+00	1223.00
IUUC-Pab-098262	Pongo abelii	77.00	0.00e+00	1275.00
IUUC-Pca-100358	Procavia capensis	70.26	0.00e+00	1094.00
IUUC-Ppe-101920	Prunus persica	35.56	1.00e-26	114.00
IUUC-Pva-102522	Pteropus vampyrus	67.89	0.00e+00	1057.00
IUUC-Rno-105200	Rattus norvegicus	74.91	0.00e+00	1244.00
IUUC-Sha-107174	Sarcophilus harrisii	77.88	0.00e+00	1305.00
IUUC-Smo-109164	Selaginella moellendorffii	50.65	2.00e-40	161.00
IUUC-Sit-110552	Setaria italica	32.50	2.00e-26	114.00
IUUC-Sly-111158	Solanum lycopersicum	39.01	2.00e-36	147.00
IUUC-Stu-112529	Solanum tuberosum	43.65	5.00e-38	152.00
IUUC-Sar-113503	Sorex araneus	73.45	0.00e+00	672.00
IUUC-Tgu-117047	Taeniopygia guttata	78.78	0.00e+00	1323.00
IUUC-Tru-118328	Takifugu rubripes	60.45	0.00e+00	1795.00
IUUC-Tsy-118953	Tarsius syrichta	48.11	0.00e+00	929.00
IUUC-Tni-120837	Tetraodon nigroviridis	68.42	0.00e+00	1237.00
IUUC-Tca-121624	Theobroma cacao	33.49	2.00e-26	114.00
IUUC-Tae-125629	Triticum aestivum	34.85	1.00e-18	88.20
IUUC-Tbe-127950	Tupaia belangeri	49.64	0.00e+00	1128.00
IUUC-Ttr-128643	Tursiops truncatus	71.90	0.00e+00	1198.00
IUUC-Vpa-130660	Vicugna pacos	77.10	0.00e+00	1038.00
IUUC-Vvi-131476	Vitis vinifera	48.73	2.00e-39	158.00
IUUC-Xtr-132869	Xenopus tropicalis	67.00	0.00e+00	1184.00
IUUC-Xma-133393	Xiphophorus maculatus	55.77	0.00e+00	1188.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence