iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044481

UUCD1 version

UUC-GoG-00750

Ensembl Protein ID

ENSGGOP00000019419.1

UniProt Accession

G3RUE1; G3RUE1_GORGO

Protein Name

Uncharacterized protein

Gene Name

TRIM65

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000010533.2	ENSGGOT00000030275.1	ENSGGOP00000025656.1
ENSGGOG00000010533.2	ENSGGOT00000028213.1	ENSGGOP00000019419.1
ENSGGOG00000010533.2	ENSGGOT00000010577.2	ENSGGOP00000010274.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.40e-06	27.0	12	51
E3 activity/RING/U-box	3.30e-08	33.9	8	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl  ++d p++lpCgH f+  C+  w       ++++ CP Cr
   Q: 12   CAICLGLYQD-PVTLPCGHNFCGACIRDW----WDRCGKA-CPECR 51
           **********.9**************888....5556665.****8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           e + C+I l l +dPv+lp+G+ +  ++I+ w +++gk cP +r+p+ +
   Q: 8    EKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKACPECREPFPD 56
           5789******************************************954 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAAQLLEEKL TCAICLGLYQ DPVTLPCGHN FCGACIRDWW DRCGKACPEC REPFPDGAEL 60
RRNVALSGVL EVGGSVHPTG MCSPASDTGW VSEAARCLLD EQMLELFCQT KGCCVCSLCT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGCGC AGCTACTGGA GGAGAAGCTG ACCTGCGCCA TCTGCCTGGG GCTCTACCAG 60
GACCCAGTGA CGCTGCCCTG CGGCCACAAC TTCTGCGGCG CCTGCATCCG GGACTGGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR003877--SPRY_dom
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010508--P:positive regulation of autophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002422	Ailuropoda melanoleuca	71.16	3.00e-136	478.00
IUUC-Ame-011110	Astyanax mexicanus	29.06	4.00e-41	162.00
IUUC-Bta-012830	Bos taurus	70.60	4.00e-173	600.00
IUUC-Bol-016180	Brassica oleracea	38.81	2.00e-11	63.50
IUUC-Bra-017905	Brassica rapa	38.81	1.00e-11	63.50
IUUC-Cja-019398	Callithrix jacchus	91.20	5.00e-129	453.00
IUUC-Cfa-021033	Canis familiaris	72.05	2.00e-139	489.00
IUUC-Cpo-021359	Cavia porcellus	66.73	9.00e-156	543.00
IUUC-Csa-023706	Chlorocebus sabaeus	85.91	0.00e+00	820.00
IUUC-Dre-027965	Danio rerio	30.36	2.00e-47	183.00
IUUC-Dno-029551	Dasypus novemcinctus	54.44	1.00e-142	500.00
IUUC-Dor-030830	Dipodomys ordii	61.07	1.00e-140	493.00
IUUC-Eca-033217	Equus caballus	75.27	6.00e-134	470.00
IUUC-Fca-036403	Felis catus	69.77	3.00e-179	621.00
IUUC-Fal-037118	Ficedula albicollis	38.80	1.00e-77	284.00
IUUC-Gmo-039107	Gadus morhua	31.89	6.00e-50	191.00
IUUC-Gac-042501	Gasterosteus aculeatus	30.32	3.00e-47	182.00
IUUC-Gma-044332	Glycine max	41.79	4.00e-13	68.90
IUUC-Hsa-046113	Homo sapiens	89.96	0.00e+00	842.00
IUUC-Itr-049000	Ictidomys tridecemlineatus	63.95	7.00e-155	540.00
IUUC-Lch-050510	Latimeria chalumnae	24.77	4.00e-35	142.00
IUUC-Loc-052279	Lepisosteus oculatus	31.27	4.00e-49	189.00
IUUC-Laf-054143	Loxodonta africana	68.86	5.00e-170	590.00
IUUC-Mcc-055216	Macaca mulatta	84.36	0.00e+00	795.00
IUUC-Meu-056384	Macropus eugenii	44.89	9.00e-108	384.00
IUUC-Mtr-058007	Medicago truncatula	43.28	2.00e-13	69.70
IUUC-Mmr-061758	Microcebus murinus	76.37	0.00e+00	632.00
IUUC-Mdo-062422	Monodelphis domestica	42.52	1.00e-58	220.00
IUUC-Mmu-063753	Mus musculus	61.35	4.00e-150	524.00
IUUC-Mpu-065880	Mustela putorius furo	67.89	6.00e-163	567.00
IUUC-Mlu-067629	Myotis lucifugus	62.60	3.00e-80	291.00
IUUC-Nle-069604	Nomascus leucogenys	94.20	8.00e-174	602.00
IUUC-Opr-070884	Ochotona princeps	60.19	9.00e-154	536.00
IUUC-Oan-073697	Ornithorhynchus anatinus	55.11	1.00e-48	185.00
IUUC-Ocu-073936	Oryctolagus cuniculus	66.67	2.00e-172	598.00
IUUC-Ogu-078203	Oryza glumaepatula	38.81	4.00e-11	62.40
IUUC-Opu-083547	Oryza punctata	38.81	6.00e-11	61.60
IUUC-Ola-087079	Oryzias latipes	26.43	2.00e-38	153.00
IUUC-Oga-087916	Otolemur garnettii	70.04	4.00e-145	507.00
IUUC-Oar-090188	Ovis aries	69.36	4.00e-156	544.00
IUUC-Ptr-091364	Pan troglodytes	99.71	0.00e+00	639.00
IUUC-Pan-092240	Papio anubis	86.29	0.00e+00	821.00
IUUC-Psi-093439	Pelodiscus sinensis	45.89	7.00e-49	186.00
IUUC-Pfo-097460	Poecilia formosa	30.81	6.00e-47	181.00
IUUC-Pab-098661	Pongo abelii	80.12	0.00e+00	715.00
IUUC-Pop-099737	Populus trichocarpa	40.30	7.00e-11	63.20
IUUC-Pva-102208	Pteropus vampyrus	69.54	2.00e-173	601.00
IUUC-Rno-105456	Rattus norvegicus	60.34	2.00e-143	502.00
IUUC-Sha-107040	Sarcophilus harrisii	49.04	9.00e-110	390.00
IUUC-Sly-110934	Solanum lycopersicum	48.39	5.00e-14	72.00
IUUC-Stu-112446	Solanum tuberosum	47.54	2.00e-13	70.10
IUUC-Sar-113700	Sorex araneus	67.78	2.00e-66	246.00
IUUC-Ssc-115895	Sus scrofa	69.36	5.00e-180	624.00
IUUC-Tru-118244	Takifugu rubripes	28.74	3.00e-37	149.00
IUUC-Tca-121416	Theobroma cacao	41.79	3.00e-13	69.30
IUUC-Tbe-127865	Tupaia belangeri	65.65	5.00e-77	280.00
IUUC-Ttr-128578	Tursiops truncatus	71.76	3.00e-172	597.00
IUUC-Vvi-131424	Vitis vinifera	41.79	2.00e-12	66.60
IUUC-Xtr-131897	Xenopus tropicalis	32.54	7.00e-64	238.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence