• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063412
Ensembl Protein ID ENSMUSP00000062593.4
UniProt Accession Q9QXV3; B2RWH0; Q9QUP8; Q9QXV4; Q9QZX3; ING1_MOUSE
Genbank Protein ID AAF16911.1; AAF16908.1; AAF16909.1; AAF16910.1; AAF09183.1; AAH16573.1; AAI47771.1; AAI47785.1
Protein Name Inhibitor of growth protein 1
Genbank Nucleotide ID AF177753; AF177755; AF177756; AF177757; AF149820; BC016573; BC147770; BC147784
Gene Name Ing1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000045969.8 ENSMUST00000054399.5 ENSMUSP00000062593.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDiRefIndexMentha
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.10e-08 36.3 211 258
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Isoform 1 inhibits p53-dependent transcriptional activation and may function as an oncoprotein. Isoform 2 acts as a negative growth regulator by cooperating with p53 in transcriptional activation of p53-responsive genes and may act as a tumor suppressor.
 Isoform 1 inhibits p53-dependent transcriptional activation and may function as an oncoprotein. Isoform 2 acts as a negative growth regulator by cooperating with p53 in transcriptional activation of p53-responsive genes and may act as a tumor suppressor.
Protein Sequence
(Fasta)
MLSPANGEQI HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDDYYEKFKR 60
ETDGTQKRRV LHCIQRALIR SQELGDEKIQ IVSQMVELVE NRSRQVDSHV ELFEAHQDIS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063412|E3,PHD|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGCGGCAGG GAGGGGAAGA GCTAGTTAGG ATCAGAGAAG AGCTGCTCCC GCCAGCCCGC 60
CCACCGTAGA TCTCCGCGCT GAAAAGAGCA CCCCTCGGGG GCCCCTTTGT CTCCAGGCCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063412|E3,PHD|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0131--Cell cycle
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0043--Tumor suppressor
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF12998--ING
SMART

SM01408--ING
SM00249--PHD
Gene Ontology

GO:0005634--C:nucleus
GO:0035064--F:methylated histone binding
GO:0008270--F:zinc ion binding
GO:0007049--P:cell cycle
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death
KEGG mmu:26356
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001945 Ailuropoda melanoleuca 94.98 1.00e-131 462.00
IUUC-Apl-003910 Anas platyrhynchos 92.45 3.00e-126 444.00
IUUC-Aca-004874 Anolis carolinensis 91.43 6.00e-124 436.00
IUUC-Aly-005815 Arabidopsis lyrata 80.00 2.00e-28 119.00
IUUC-Acl-008091 Aspergillus clavatus 52.11 8.00e-19 89.00
IUUC-Ate-010297 Aspergillus terreus 52.11 7.00e-19 89.40
IUUC-Ame-011262 Astyanax mexicanus 67.24 1.00e-96 345.00
IUUC-Bta-013507 Bos taurus 90.17 4.00e-94 337.00
IUUC-Cja-018925 Callithrix jacchus 89.96 7.00e-124 436.00
IUUC-Cfa-020947 Canis familiaris 94.62 3.00e-130 457.00
IUUC-Cpo-022286 Cavia porcellus 91.53 9.00e-101 360.00
IUUC-Csa-023825 Chlorocebus sabaeus 89.61 2.00e-123 434.00
IUUC-Cho-024577 Choloepus hoffmanni 94.85 8.00e-103 365.00
IUUC-Cne-027005 Cryptococcus neoformans 45.95 4.00e-16 79.00
IUUC-Dno-029834 Dasypus novemcinctus 94.98 1.00e-130 459.00
IUUC-Dor-030315 Dipodomys ordii 93.16 4.00e-113 401.00
IUUC-Ete-032408 Echinops telfairi 90.21 5.00e-96 344.00
IUUC-Eca-034244 Equus caballus 94.44 8.00e-105 372.00
IUUC-Fca-035391 Felis catus 89.19 8.00e-111 392.00
IUUC-Fal-036838 Ficedula albicollis 91.40 3.00e-125 441.00
IUUC-Fox-037925 Fusarium oxysporum 64.71 9.00e-20 91.30
IUUC-Gga-040619 Gallus gallus 92.47 4.00e-126 443.00
IUUC-Gac-041996 Gasterosteus aculeatus 64.18 4.00e-95 340.00
IUUC-Ggo-045481 Gorilla gorilla 87.71 5.00e-97 348.00
IUUC-Hsa-046170 Homo sapiens 87.71 4.00e-97 348.00
IUUC-Itr-048440 Ictidomys tridecemlineatus 94.87 4.00e-104 370.00
IUUC-Lch-050397 Latimeria chalumnae 88.89 7.00e-123 432.00
IUUC-Loc-052038 Lepisosteus oculatus 80.62 2.00e-99 354.00
IUUC-Laf-054126 Loxodonta africana 96.42 8.00e-133 466.00
IUUC-Mcc-055031 Macaca mulatta 87.23 9.00e-96 343.00
IUUC-Meu-056248 Macropus eugenii 90.76 2.00e-99 355.00
IUUC-Mga-059217 Meleagris gallopavo 91.42 3.00e-98 350.00
IUUC-Mmr-061581 Microcebus murinus 95.88 3.00e-111 394.00
IUUC-Mdo-062452 Monodelphis domestica 93.55 8.00e-128 449.00
IUUC-Mpu-066479 Mustela putorius furo 94.02 5.00e-104 370.00
IUUC-Mlu-067586 Myotis lucifugus 80.43 1.00e-119 422.00
IUUC-Nle-069122 Nomascus leucogenys 89.96 1.00e-123 436.00
IUUC-Opr-070835 Ochotona princeps 84.98 1.00e-86 312.00
IUUC-Oan-073023 Ornithorhynchus anatinus 91.40 8.00e-124 436.00
IUUC-Ocu-073779 Oryctolagus cuniculus 91.25 2.00e-97 348.00
IUUC-Ola-086891 Oryzias latipes 65.36 2.00e-95 342.00
IUUC-Oga-087954 Otolemur garnettii 95.34 2.00e-132 465.00
IUUC-Oar-090006 Ovis aries 92.11 4.00e-127 447.00
IUUC-Ptr-090589 Pan troglodytes 90.32 2.00e-124 438.00
IUUC-Pan-091896 Papio anubis 87.23 6.00e-96 344.00
IUUC-Psi-093266 Pelodiscus sinensis 93.19 5.00e-128 450.00
IUUC-Pma-094265 Petromyzon marinus 73.97 5.00e-33 133.00
IUUC-Pfo-097531 Poecilia formosa 61.04 9.00e-93 333.00
IUUC-Pab-098253 Pongo abelii 90.32 3.00e-124 437.00
IUUC-Pva-102753 Pteropus vampyrus 83.01 6.00e-92 330.00
IUUC-Rno-105964 Rattus norvegicus 99.15 2.00e-96 345.00
IUUC-Sha-107270 Sarcophilus harrisii 92.83 3.00e-126 444.00
IUUC-Tgu-116822 Taeniopygia guttata 92.47 1.00e-126 446.00
IUUC-Tni-119980 Tetraodon nigroviridis 57.00 1.00e-81 296.00
IUUC-Tre-121950 Trichoderma reesei 64.29 2.00e-19 91.30
IUUC-Tvi-122341 Trichoderma virens 62.50 4.00e-16 77.00
IUUC-Ttr-128672 Tursiops truncatus 92.34 3.00e-102 364.00
IUUC-Xtr-132200 Xenopus tropicalis 85.30 2.00e-116 411.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved