iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000019253.8	ENSRNOT00000041815.6	ENSRNOP00000039940.4
ENSRNOG00000019253.8	ENSRNOT00000058891.4	ENSRNOP00000055678.4

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.40e-11	42.4	102	152

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeq.degWlkgvkelegkrGlfPen 57
            ++lyd  a++ deL+++kGd+++v+e ++q   gW+ +   l+g++G++P n
   Q: 102  AKALYDNVAESPDELSFRKGDIMTVLERDTQgLDGWWLC--SLHGRQGIVPGN 152
           689***********************55555168*****..9*********98 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MKYLVSVGAG PARRAGGLED VSWGPRVSRR PQSYRAARHV NESLPRSAFR VPAAHGASVT 60
PSAALGSGLP ETQPEAVCRG TEKPRFAEGC KPAASRDKNV LAKALYDNVA ESPDELSFRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACGCGGGT AGCACGGCCT CTGGCCGTGG AGCACCATGA AGTACCTGGT GAGTGTGGGC 60
GCGGGGCCGG CCAGGCGGGC GGGCGGTCTG GAGGACGTTT CCTGGGGGCC CCGAGTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR028848--BCAR1
IPR021901--CAS_DUF3513
IPR014928--Serine_rich
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3
IPR015224--Talin_cent

PROSITE

PS50002--SH3

Pfam

PF12026--DUF3513
PF08824--Serine_rich
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA

SMART

SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005737--C:cytoplasm
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0004871--F:signal transducer activity
GO:0007015--P:actin filament organization
GO:0050853--P:B cell receptor signaling pathway
GO:0060326--P:cell chemotaxis
GO:0035729--P:cellular response to hepatocyte growth factor stimulus
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0048012--P:hepatocyte growth factor receptor signaling pathway
GO:0007229--P:integrin-mediated signaling pathway
GO:0048008--P:platelet-derived growth factor receptor signaling pathway
GO:0010595--P:positive regulation of endothelial cell migration
GO:0048010--P:vascular endothelial growth factor receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001208	Ailuropoda melanoleuca	88.51	0.00e+00	1157.00
IUUC-Apl-003391	Anas platyrhynchos	37.70	9.00e-138	484.00
IUUC-Aca-004548	Anolis carolinensis	39.30	8.00e-142	497.00
IUUC-Bta-013197	Bos taurus	81.72	0.00e+00	1134.00
IUUC-Cja-018921	Callithrix jacchus	90.80	0.00e+00	1332.00
IUUC-Cfa-020772	Canis familiaris	90.70	0.00e+00	1259.00
IUUC-Cpo-022455	Cavia porcellus	90.34	0.00e+00	1285.00
IUUC-Csa-023660	Chlorocebus sabaeus	91.15	0.00e+00	1331.00
IUUC-Cin-025595	Ciona intestinalis	27.25	3.00e-44	173.00
IUUC-Dre-028389	Danio rerio	53.54	0.00e+00	824.00
IUUC-Dno-028907	Dasypus novemcinctus	86.44	0.00e+00	1152.00
IUUC-Dor-030300	Dipodomys ordii	95.29	9.00e-169	587.00
IUUC-Dme-031580	Drosophila melanogaster	28.43	9.00e-39	155.00
IUUC-Ete-032641	Echinops telfairi	93.48	5.00e-128	452.00
IUUC-Eca-033297	Equus caballus	91.62	0.00e+00	1299.00
IUUC-Eeu-035356	Erinaceus europaeus	84.85	0.00e+00	915.00
IUUC-Fca-036302	Felis catus	89.78	0.00e+00	1199.00
IUUC-Fal-036729	Ficedula albicollis	64.50	0.00e+00	1061.00
IUUC-Gga-040285	Gallus gallus	62.63	0.00e+00	1003.00
IUUC-Ggo-045534	Gorilla gorilla	91.15	0.00e+00	1315.00
IUUC-Hsa-046672	Homo sapiens	91.26	0.00e+00	1318.00
IUUC-Itr-048045	Ictidomys tridecemlineatus	92.42	0.00e+00	1318.00
IUUC-Lch-049837	Latimeria chalumnae	60.02	0.00e+00	914.00
IUUC-Loc-052010	Lepisosteus oculatus	54.99	0.00e+00	835.00
IUUC-Laf-053978	Loxodonta africana	89.22	0.00e+00	1209.00
IUUC-Mcc-055551	Macaca mulatta	90.69	0.00e+00	1301.00
IUUC-Meu-056006	Macropus eugenii	65.14	0.00e+00	878.00
IUUC-Mga-060136	Meleagris gallopavo	39.96	8.00e-147	514.00
IUUC-Mmr-061269	Microcebus murinus	90.22	0.00e+00	1342.00
IUUC-Mmu-063741	Mus musculus	97.13	0.00e+00	1416.00
IUUC-Mpu-066694	Mustela putorius furo	88.85	0.00e+00	1192.00
IUUC-Mlu-067377	Myotis lucifugus	88.06	0.00e+00	1229.00
IUUC-Nle-069243	Nomascus leucogenys	88.76	0.00e+00	697.00
IUUC-Opr-070611	Ochotona princeps	84.25	0.00e+00	1156.00
IUUC-Ont-071724	Oreochromis niloticus	51.18	0.00e+00	756.00
IUUC-Oan-073477	Ornithorhynchus anatinus	51.64	4.00e-46	176.00
IUUC-Ocu-074436	Oryctolagus cuniculus	91.70	0.00e+00	1054.00
IUUC-Ola-086487	Oryzias latipes	48.54	0.00e+00	703.00
IUUC-Oga-088966	Otolemur garnettii	91.50	0.00e+00	1358.00
IUUC-Oar-089394	Ovis aries	76.80	2.00e-128	453.00
IUUC-Ptr-090896	Pan troglodytes	91.49	0.00e+00	1351.00
IUUC-Pan-092021	Papio anubis	90.92	0.00e+00	1303.00
IUUC-Pfo-096333	Poecilia formosa	48.46	4.00e-31	130.00
IUUC-Pab-098732	Pongo abelii	86.45	0.00e+00	1199.00
IUUC-Pca-100841	Procavia capensis	88.81	2.00e-177	616.00
IUUC-Pva-102291	Pteropus vampyrus	83.43	0.00e+00	847.00
IUUC-Sha-106605	Sarcophilus harrisii	62.99	2.00e-88	320.00
IUUC-Spo-108375	Schizosaccharomyces pombe	40.58	8.00e-09	57.00
IUUC-Ssc-116113	Sus scrofa	87.05	0.00e+00	1189.00
IUUC-Tgu-117420	Taeniopygia guttata	38.23	9.00e-141	494.00
IUUC-Tru-118044	Takifugu rubripes	48.20	5.00e-32	132.00
IUUC-Ttr-128533	Tursiops truncatus	87.82	0.00e+00	1198.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence