iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000005655.4	ENSCAFT00000043542.2	ENSCAFP00000037748.1
ENSCAFG00000005655.4	ENSCAFT00000009108.4	ENSCAFP00000008447.3
ENSCAFG00000005655.4	ENSCAFT00000044666.2	ENSCAFP00000035963.1
ENSCAFG00000005655.4	ENSCAFT00000047262.1	ENSCAFP00000039203.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-26	91.8	330	365
UBD/Beta-Prp	1.40e-44	152.7	328	605

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f ++  ll++G+ D  i++W++  g+l
   Q: 330  HLSEVNAVCFgPNsSLLATGGADRLIHLWNVVGGRL 365
           99*********7779***************987765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v+f p++sllatg++d+ i +w+v  g l   ++l+g  + +t+v+f+p+g+  + +   +++++w +   +   tl+gh
   Q: 328  DAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLeaNQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGEAQSKETLSGH 416
           689999********************************88899******************9999999********************* PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t s+ +  + +v+ +    +++sG++D+++r+Wd++  ++ +      +++
   Q: 417  TDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TISVLSYCNDVVCGD---HVIISGHNDQKIRFWDSRVPCCTQVIP--VQGR 499
           ************************************9.666666555555555...5*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sl++++++ +l+s+s+d t+k+ dl+ +++ + +++       d++k   fsp+  + + gs Dg ++iWd+++g+l ++l +++ +
   Q: 500  VTSLNLSHDQLHLLSCSRDDTLKIIDLRVSNIRQVFRADGfrcgsDWTK-AVFSPDRSYALAGSWDGALYIWDVDTGKLEGSLRGPHCT 587
           ****************************888855555544445526666.8899*********************************76 PP
   S: 267  visvavlsfgdnvlvlgs 284
            +   +++++++++ +gs
   Q: 588  AVNAVAWCYSGSHVHSGS 605
           666666799999998887 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAGPGARWKR HIVRQLRQRD RTQKALFLEL VPAYNCLLEK AELLARISEK LQPKPNDVTP 60
ATLQGPWEEE SGPDSDLVPS SSTLRVKWQE KEEGLRLVCG EMAYQVVAKS AALGALESTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGATGGTGA GTGAAGGTCC CGATCTCTCC GGTCAGACTG GACTGCTGGC TCCTCCTTCT 60
CCCACCTGGA GCTGCGGAGC AGAGTCCGGG CGAGCCCTCC CATCCCAGCA GGGAAGCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005654--C:nucleoplasm
GO:0000045--P:autophagosome assembly
GO:0039689--P:negative stranded viral RNA replication

KEGG

cfa:485205

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	72.93	0.00e+00	814.00
IUUC-Aca-004664	Anolis carolinensis	70.87	2.00e-98	351.00
IUUC-Ame-011152	Astyanax mexicanus	43.22	2.00e-119	422.00
IUUC-Bta-013118	Bos taurus	82.92	0.00e+00	889.00
IUUC-Cja-020002	Callithrix jacchus	82.57	0.00e+00	889.00
IUUC-Cpo-022476	Cavia porcellus	79.47	0.00e+00	867.00
IUUC-Csa-024134	Chlorocebus sabaeus	82.28	0.00e+00	889.00
IUUC-Cho-024853	Choloepus hoffmanni	66.67	1.00e-166	579.00
IUUC-Dre-027949	Danio rerio	40.75	3.00e-125	442.00
IUUC-Dno-029683	Dasypus novemcinctus	80.65	0.00e+00	743.00
IUUC-Dor-030897	Dipodomys ordii	75.25	0.00e+00	867.00
IUUC-Ete-032957	Echinops telfairi	93.33	2.00e-124	439.00
IUUC-Eca-033303	Equus caballus	89.46	1.00e-156	545.00
IUUC-Eeu-035336	Erinaceus europaeus	72.77	2.00e-147	515.00
IUUC-Fca-036232	Felis catus	88.94	0.00e+00	1031.00
IUUC-Ggo-045130	Gorilla gorilla	74.79	0.00e+00	651.00
IUUC-Hsa-046359	Homo sapiens	83.86	0.00e+00	875.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	81.32	0.00e+00	896.00
IUUC-Lch-050669	Latimeria chalumnae	53.70	6.00e-91	327.00
IUUC-Loc-052789	Lepisosteus oculatus	42.64	9.00e-113	400.00
IUUC-Laf-053699	Loxodonta africana	81.82	0.00e+00	869.00
IUUC-Mcc-055657	Macaca mulatta	77.49	0.00e+00	798.00
IUUC-Meu-056639	Macropus eugenii	46.98	2.00e-102	366.00
IUUC-Mmr-061314	Microcebus murinus	76.81	0.00e+00	811.00
IUUC-Mdo-061841	Monodelphis domestica	61.37	0.00e+00	667.00
IUUC-Mmu-064065	Mus musculus	79.20	0.00e+00	891.00
IUUC-Mpu-066742	Mustela putorius furo	88.83	0.00e+00	947.00
IUUC-Mlu-067019	Myotis lucifugus	84.28	0.00e+00	790.00
IUUC-Nle-069037	Nomascus leucogenys	83.86	0.00e+00	913.00
IUUC-Opr-071039	Ochotona princeps	76.51	0.00e+00	827.00
IUUC-Oan-073431	Ornithorhynchus anatinus	71.66	4.00e-133	467.00
IUUC-Ocu-074772	Oryctolagus cuniculus	80.10	0.00e+00	769.00
IUUC-Oga-088188	Otolemur garnettii	82.28	0.00e+00	861.00
IUUC-Oar-090231	Ovis aries	77.67	0.00e+00	877.00
IUUC-Ptr-091434	Pan troglodytes	81.26	0.00e+00	835.00
IUUC-Pan-091868	Papio anubis	82.87	0.00e+00	884.00
IUUC-Psi-093652	Pelodiscus sinensis	60.32	1.00e-151	529.00
IUUC-Pfo-096960	Poecilia formosa	40.07	5.00e-95	341.00
IUUC-Pab-097776	Pongo abelii	83.19	0.00e+00	823.00
IUUC-Pca-100220	Procavia capensis	61.97	1.00e-163	569.00
IUUC-Pva-103135	Pteropus vampyrus	86.21	0.00e+00	843.00
IUUC-Rno-105529	Rattus norvegicus	78.87	0.00e+00	912.00
IUUC-Sha-107062	Sarcophilus harrisii	60.99	0.00e+00	688.00
IUUC-Sar-113109	Sorex araneus	59.00	2.00e-126	446.00
IUUC-Ssc-115271	Sus scrofa	84.43	0.00e+00	876.00
IUUC-Ttr-128267	Tursiops truncatus	86.34	0.00e+00	672.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence