iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066742

Ensembl Protein ID

ENSMPUP00000009703.1

UniProt Accession

M3YEE6; M3YEE6_MUSPF

Genbank Protein ID

ENSMPUP00000009703

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01069183

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000009778.1	ENSMPUT00000009860.1	ENSMPUP00000009703.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-26	91.7	336	371
UBD/Beta-Prp	5.30e-46	157.1	334	619

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f ++  ll++G+ D  i++W++  g+l
   Q: 336  HLSEVNAVCFgPSsSLLATGGADRLIQLWNVVGGRL 371
           99*********6669***************987765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v+f p++sllatg++d+ i++w+v  g l   ++l+g  + +t+v+f+p+g+  + +   +++++w +   +   tl+gh
   Q: 334  DAHLSEVNAVCFGPSSSLLATGGADRLIQLWNVVGGRLeaNQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQIWKVGEVQSKETLSGH 422
           789999********************************88899******************9999999********************* PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++  ++ +      +++
   Q: 423  TDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TINVLS---YCNDVVCGDHVIISGHYDQKIRFWDSRVPCCTQVIP--VQGR 505
           ************************************9.666665...4555555556*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sl++++++ +l+s+s+d t+k+ dl+ +++ + +++       d++k   fsp+  + + gs Dg ++iW++++g+l ++l +++ +
   Q: 506  VTSLNLSYDQLHLLSCSRDDTLKVIDLRVSNIRQVFRADGfrcgsDWTK-AVFSPDRSYALAGSWDGALYIWNVDTGKLEGSLRGPHCT 593
           ****************************888855555544445526666.8899*********************************88 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            i   +++ +++++v++++  kv +w
   Q: 594  AINAVAWCASGSHVVSVDQARKVVLW 619
           8888888************9999999 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAGSGPLGVP NARWKRHIVR QLRQRDRAQK ALFLELVPAY NRLLEKAELL AWISEKLQPE 60
PNDVTPTTLQ GPWEEDSGPD SDEIPSPTTL RVKWQEEEEG LRRVCGEMAY QVVEKSAALG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGGT CCGGGCCCCT CGGCGTGCCG AACGCCCGCT GGAAACGCCA CATAGTGCGG 60
CAGCTTCGGC AGCGGGACCG CGCGCAGAAG GCCCTCTTCC TGGAGCTGGT GCCGGCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	73.53	0.00e+00	847.00
IUUC-Aca-004664	Anolis carolinensis	71.30	1.00e-99	355.00
IUUC-Ame-011152	Astyanax mexicanus	43.47	2.00e-122	432.00
IUUC-Bta-013118	Bos taurus	83.84	0.00e+00	931.00
IUUC-Cja-020002	Callithrix jacchus	82.61	0.00e+00	909.00
IUUC-Cfa-020878	Canis familiaris	88.83	0.00e+00	1002.00
IUUC-Cpo-022476	Cavia porcellus	81.05	0.00e+00	895.00
IUUC-Csa-024134	Chlorocebus sabaeus	82.77	0.00e+00	914.00
IUUC-Cho-024853	Choloepus hoffmanni	68.81	1.00e-174	605.00
IUUC-Dre-027949	Danio rerio	42.83	2.00e-133	469.00
IUUC-Dno-029683	Dasypus novemcinctus	82.39	0.00e+00	772.00
IUUC-Dor-030897	Dipodomys ordii	77.26	0.00e+00	910.00
IUUC-Ete-032957	Echinops telfairi	92.80	2.00e-128	452.00
IUUC-Eca-033303	Equus caballus	89.51	2.00e-163	567.00
IUUC-Eeu-035336	Erinaceus europaeus	72.52	8.00e-150	523.00
IUUC-Fca-036232	Felis catus	88.85	0.00e+00	1054.00
IUUC-Gmo-038880	Gadus morhua	50.00	3.00e-71	262.00
IUUC-Gac-042500	Gasterosteus aculeatus	39.59	5.00e-93	335.00
IUUC-Ggo-045130	Gorilla gorilla	85.30	0.00e+00	665.00
IUUC-Hsa-046359	Homo sapiens	84.21	0.00e+00	895.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	82.35	0.00e+00	931.00
IUUC-Lch-050669	Latimeria chalumnae	53.75	2.00e-95	342.00
IUUC-Loc-052789	Lepisosteus oculatus	44.16	5.00e-123	434.00
IUUC-Laf-053699	Loxodonta africana	83.65	0.00e+00	916.00
IUUC-Mcc-055657	Macaca mulatta	78.51	0.00e+00	828.00
IUUC-Meu-056639	Macropus eugenii	49.80	3.00e-113	402.00
IUUC-Mmr-061314	Microcebus murinus	78.16	0.00e+00	837.00
IUUC-Mdo-061841	Monodelphis domestica	64.95	0.00e+00	700.00
IUUC-Mmu-064065	Mus musculus	80.36	0.00e+00	927.00
IUUC-Mlu-067019	Myotis lucifugus	85.20	0.00e+00	821.00
IUUC-Nle-069037	Nomascus leucogenys	84.21	0.00e+00	934.00
IUUC-Opr-071039	Ochotona princeps	79.16	0.00e+00	872.00
IUUC-Oan-073431	Ornithorhynchus anatinus	72.22	3.00e-139	487.00
IUUC-Ocu-074772	Oryctolagus cuniculus	82.53	0.00e+00	816.00
IUUC-Ola-086964	Oryzias latipes	52.61	2.00e-84	305.00
IUUC-Oga-088188	Otolemur garnettii	82.71	0.00e+00	888.00
IUUC-Oar-090231	Ovis aries	77.83	0.00e+00	910.00
IUUC-Ptr-091434	Pan troglodytes	81.64	0.00e+00	855.00
IUUC-Pan-091868	Papio anubis	83.84	0.00e+00	914.00
IUUC-Psi-093652	Pelodiscus sinensis	62.04	3.00e-159	554.00
IUUC-Pfo-096960	Poecilia formosa	41.87	2.00e-105	376.00
IUUC-Pab-097776	Pongo abelii	83.39	0.00e+00	844.00
IUUC-Pca-100220	Procavia capensis	63.99	2.00e-173	602.00
IUUC-Pva-103135	Pteropus vampyrus	86.63	0.00e+00	876.00
IUUC-Rno-105529	Rattus norvegicus	78.46	0.00e+00	943.00
IUUC-Sha-107062	Sarcophilus harrisii	64.59	0.00e+00	736.00
IUUC-Sar-113109	Sorex araneus	65.80	5.00e-133	467.00
IUUC-Ssc-115271	Sus scrofa	85.32	0.00e+00	911.00
IUUC-Ttr-128267	Tursiops truncatus	81.58	0.00e+00	877.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence