iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033633

UUCD1 version

UUC-EqC-00315

Ensembl Protein ID

ENSECAP00000006399.1

UniProt Accession

F6V286; F6V286_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRIM68

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000008318.1	ENSECAT00000008532.1	ENSECAP00000006399.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.50e-09	36.1	16	61
E3 activity/RING/U-box	6.10e-06	26.4	10	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw..pglknssskefrCPlCr 46
           C+iC++ +++ p++ +CgH f+++Cl   w  pg    + +  +CPlCr
   Q: 16   CPICMTFLRE-PVSIDCGHSFCHSCLsGLWevPGEL--QDQGYTCPLCR 61
           ********88.***************8778656665..9999******8 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwl......asggktcPvtrqplteedlvPnltlrrliq 66
           + ee  CpI ++  r+Pv + +G+++  s++          +++g tcP++r+p+++++l Pn  l ++++
   Q: 10   IVEEVACPICMTFLREPVSIDCGHSFCHSCLSGLWevpgelQDQGYTCPLCRAPVQPRNLRPNWQLASVVE 80
           67999**************************9865444444444449****************99988776 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MDPAALVEAI VEEVACPICM TFLREPVSID CGHSFCHSCL SGLWEVPGEL QDQGYTCPLC 60
RAPVQPRNLR PNWQLASVVE KVRLLELHAG VGLKGDVCEL HSKQLKMFCR EDGLVMCEAC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCTGGTTTT CTCCATGTTT TGAGGAGGGT GTGAGAAGGA CCATGGATCC TGCAGCACTA 60
GTGGAAGCCA TTGTGGAAGA AGTGGCCTGT CCCATCTGCA TGACCTTCCT GAGGGAGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005730--C:nucleolus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0051865--P:protein autoubiquitination
GO:0060765--P:regulation of androgen receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002078	Ailuropoda melanoleuca	84.27	0.00e+00	735.00
IUUC-Apl-003968	Anas platyrhynchos	39.65	1.00e-80	293.00
IUUC-Bta-012800	Bos taurus	79.54	0.00e+00	746.00
IUUC-Cja-019382	Callithrix jacchus	81.47	0.00e+00	723.00
IUUC-Cfa-020686	Canis familiaris	81.20	1.00e-161	562.00
IUUC-Csa-023952	Chlorocebus sabaeus	81.90	0.00e+00	716.00
IUUC-Cho-024811	Choloepus hoffmanni	72.62	6.00e-178	616.00
IUUC-Dre-028631	Danio rerio	30.38	2.00e-52	200.00
IUUC-Dno-029361	Dasypus novemcinctus	79.96	0.00e+00	701.00
IUUC-Dor-030703	Dipodomys ordii	76.29	0.00e+00	670.00
IUUC-Ete-033159	Echinops telfairi	88.72	2.00e-103	369.00
IUUC-Eeu-034686	Erinaceus europaeus	72.14	0.00e+00	649.00
IUUC-Fca-035750	Felis catus	85.24	0.00e+00	741.00
IUUC-Gga-040491	Gallus gallus	40.95	6.00e-89	321.00
IUUC-Gac-042288	Gasterosteus aculeatus	36.38	5.00e-69	254.00
IUUC-Ggo-045524	Gorilla gorilla	81.03	0.00e+00	711.00
IUUC-Hsa-046031	Homo sapiens	80.82	0.00e+00	738.00
IUUC-Itr-048898	Ictidomys tridecemlineatus	77.80	0.00e+00	677.00
IUUC-Laf-054264	Loxodonta africana	83.04	0.00e+00	757.00
IUUC-Mcc-055388	Macaca mulatta	81.90	0.00e+00	716.00
IUUC-Mmr-060612	Microcebus murinus	76.72	0.00e+00	668.00
IUUC-Mmu-063761	Mus musculus	73.71	0.00e+00	705.00
IUUC-Mpu-066319	Mustela putorius furo	84.70	0.00e+00	741.00
IUUC-Mlu-067368	Myotis lucifugus	80.13	0.00e+00	703.00
IUUC-Nle-069702	Nomascus leucogenys	80.82	0.00e+00	709.00
IUUC-Opr-070810	Ochotona princeps	69.61	6.00e-167	580.00
IUUC-Ont-072259	Oreochromis niloticus	32.87	2.00e-64	239.00
IUUC-Oga-088935	Otolemur garnettii	78.45	0.00e+00	689.00
IUUC-Oar-089940	Ovis aries	82.76	0.00e+00	728.00
IUUC-Ptr-091056	Pan troglodytes	81.25	0.00e+00	712.00
IUUC-Pan-092165	Papio anubis	81.68	0.00e+00	711.00
IUUC-Pfo-096858	Poecilia formosa	33.33	2.00e-65	243.00
IUUC-Pab-098415	Pongo abelii	79.67	1.00e-131	462.00
IUUC-Pca-100470	Procavia capensis	74.62	0.00e+00	696.00
IUUC-Pva-102603	Pteropus vampyrus	77.11	0.00e+00	659.00
IUUC-Rno-105709	Rattus norvegicus	71.33	0.00e+00	671.00
IUUC-Sar-113101	Sorex araneus	72.36	5.00e-129	453.00
IUUC-Ssc-115920	Sus scrofa	80.17	0.00e+00	704.00
IUUC-Tgu-116998	Taeniopygia guttata	42.61	6.00e-81	294.00
IUUC-Tni-120295	Tetraodon nigroviridis	34.60	6.00e-64	238.00
IUUC-Tbe-127512	Tupaia belangeri	72.16	4.00e-146	510.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence