iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120168

UUCD1 version

UUC-TeN-00745

Ensembl Protein ID

ENSTNIP00000021422.1

UniProt Accession

H3DLM4; H3DLM4_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000018256.1	ENSTNIT00000021657.1	ENSTNIP00000021422.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.30e-117	391.5	523	823

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dl++rl+v f gEegld+gGv+re+++lls+e+ np+++lf+y  +d+++lq+np+s++ np+hlk+F+f+Gr++++al++g+++d+
   Q: 523  PQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYI-NPDHLKYFKFIGRFIAMALFHGKFIDT 610
           5899********************************************************9.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            +s +fyk++l+k+l l+dle++dpe+y+sl +ik+n   +iee++l++ fsv++eilge++++eLkp+G ni+Vt++NkeeY++lv+e
   Q: 611  GFSLPFYKRILNKPLALKDLESIDPEFYNSLIWIKDN---NIEECALEMFFSVDKEILGEVTTHELKPDGGNIQVTEKNKEEYIRLVAE 696
           ***********************************99...9************************************************ PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +rl +g++eq++af eGfnev+p++ l++F+++ele+++cG++eid+ d++++t y++ y ++s++i wFw++++e+++e+r ++LqFv
   Q: 697  WRLSRGVEEQTQAFFEGFNEVLPQQYLQYFDAKELEVMLCGMQEIDLMDWQRNTIYRH-YARSSKQILWFWQFVKEMDNEKRMRLLQFV 784
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirkdasddrlPssnT 303
           Tg++rlP+gGfa+l+    p++f+i+k +++++lP+s+T
   Q: 785  TGTCRLPVGGFADLMgsngPQKFCIEKVGKENWLPRSHT 823
           **************************************9 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MKAQLQVTVL SAKLRENKRN WFGPSPYVEV AVDGQSKRTD KCNNTYTPKW KQPLTVIVTP 60
VSKLVFRVWS HQTLKADILL GLATLDISET LKANNLKLCE VVHTLQLSSD RDPRGDVVGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGGCCC AATTGCAAGT CACAGGTAAG ATATATTTAA AAATATGTCA GCTGCAGTAA 60
ACTCTGTGCC AGTAAAAGGT CTGTAAATGT GGCAATATGA GTAATTTCAT AGCATTTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002302	Ailuropoda melanoleuca	73.56	0.00e+00	1244.00
IUUC-Apl-003752	Anas platyrhynchos	71.85	0.00e+00	1229.00
IUUC-Aca-005338	Anolis carolinensis	72.46	0.00e+00	1224.00
IUUC-Ame-010601	Astyanax mexicanus	92.34	0.00e+00	1115.00
IUUC-Bta-012782	Bos taurus	89.63	0.00e+00	1053.00
IUUC-Cja-018899	Callithrix jacchus	84.80	0.00e+00	1059.00
IUUC-Cfa-020648	Canis familiaris	72.73	0.00e+00	1231.00
IUUC-Cpo-022073	Cavia porcellus	72.99	0.00e+00	1245.00
IUUC-Csa-023252	Chlorocebus sabaeus	74.21	0.00e+00	1248.00
IUUC-Cho-024695	Choloepus hoffmanni	84.12	0.00e+00	1068.00
IUUC-Dre-028451	Danio rerio	80.36	0.00e+00	1329.00
IUUC-Dno-029884	Dasypus novemcinctus	73.32	0.00e+00	1260.00
IUUC-Eca-033793	Equus caballus	75.73	0.00e+00	1248.00
IUUC-Fca-035605	Felis catus	73.71	0.00e+00	1261.00
IUUC-Fal-037126	Ficedula albicollis	86.99	0.00e+00	1060.00
IUUC-Gmo-038596	Gadus morhua	74.64	0.00e+00	1190.00
IUUC-Gga-040832	Gallus gallus	87.46	0.00e+00	1059.00
IUUC-Gac-041520	Gasterosteus aculeatus	80.07	0.00e+00	1350.00
IUUC-Ggo-044535	Gorilla gorilla	71.55	0.00e+00	1220.00
IUUC-Hsa-046564	Homo sapiens	70.57	0.00e+00	1229.00
IUUC-Itr-048918	Ictidomys tridecemlineatus	85.17	0.00e+00	1058.00
IUUC-Lch-050454	Latimeria chalumnae	74.58	0.00e+00	1257.00
IUUC-Loc-052647	Lepisosteus oculatus	74.42	0.00e+00	1323.00
IUUC-Laf-054383	Loxodonta africana	72.75	0.00e+00	1247.00
IUUC-Mcc-055532	Macaca mulatta	74.21	0.00e+00	1247.00
IUUC-Mga-059661	Meleagris gallopavo	87.28	0.00e+00	1057.00
IUUC-Mmr-061135	Microcebus murinus	74.12	0.00e+00	1261.00
IUUC-Mdo-062505	Monodelphis domestica	74.19	0.00e+00	1249.00
IUUC-Mmu-063375	Mus musculus	85.51	0.00e+00	1061.00
IUUC-Mpu-066203	Mustela putorius furo	73.32	0.00e+00	1244.00
IUUC-Mlu-067837	Myotis lucifugus	73.68	0.00e+00	1247.00
IUUC-Nle-069244	Nomascus leucogenys	85.99	0.00e+00	1053.00
IUUC-Opr-070585	Ochotona princeps	86.17	0.00e+00	1050.00
IUUC-Ont-071798	Oreochromis niloticus	84.57	0.00e+00	1376.00
IUUC-Ocu-074298	Oryctolagus cuniculus	85.69	0.00e+00	1063.00
IUUC-Ola-086526	Oryzias latipes	88.11	0.00e+00	1090.00
IUUC-Oga-088167	Otolemur garnettii	68.11	0.00e+00	1145.00
IUUC-Ptr-090819	Pan troglodytes	69.54	0.00e+00	1179.00
IUUC-Pan-092454	Papio anubis	74.21	0.00e+00	1248.00
IUUC-Psi-093319	Pelodiscus sinensis	71.36	0.00e+00	1208.00
IUUC-Pfo-096937	Poecilia formosa	95.65	0.00e+00	1132.00
IUUC-Pab-097580	Pongo abelii	61.70	0.00e+00	1019.00
IUUC-Pca-100923	Procavia capensis	75.04	0.00e+00	927.00
IUUC-Pva-103209	Pteropus vampyrus	74.21	0.00e+00	1202.00
IUUC-Rno-104924	Rattus norvegicus	74.00	0.00e+00	1251.00
IUUC-Sha-107175	Sarcophilus harrisii	75.30	0.00e+00	1263.00
IUUC-Sar-113761	Sorex araneus	89.07	0.00e+00	1045.00
IUUC-Tgu-116632	Taeniopygia guttata	82.66	0.00e+00	966.00
IUUC-Tru-118658	Takifugu rubripes	83.69	0.00e+00	1456.00
IUUC-Tsy-119198	Tarsius syrichta	66.59	0.00e+00	1115.00
IUUC-Tbe-127756	Tupaia belangeri	73.37	0.00e+00	823.00
IUUC-Vpa-130103	Vicugna pacos	72.54	0.00e+00	878.00
IUUC-Xtr-132885	Xenopus tropicalis	85.71	0.00e+00	1063.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence