iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036990

Ensembl Protein ID

ENSFALP00000012538.1

UniProt Accession

U3KBY4; U3KBY4_FICAL

Genbank Protein ID

ENSFALP00000012538

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01002349

Gene Name

RACK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000012004.1	ENSFALT00000012588.1	ENSFALP00000012538.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-28	96.0	143	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf....sdtllvsGsdDgtikvWDlrt 32
           H+++v+c++f    s++++vs+++D+ +kvW+l  
   Q: 143  HSEWVSCVRFspnsSNPIIVSCGWDKLVKVWNLAN 177
           9**********98544****************865 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTI IMWKLTRDET NYGIPQRALR 60
PPPPPSGGCG VSSGGCGVSP GGCGVSSGGF GVSSGGLGFR GLGSVPLGLG SVLVLGSVPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGAGC AGATGACCCT GCGCGGGACC CTGAAGGGCC ACAACGGCTG GGTGACGCAG 60
ATCGCCACCA CGCCGCAGTT CCCCGACATG ATCCTGTCGG CCTCGCGCGG TGCGCGCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0070062--C:extracellular exosome
GO:1990630--C:IRE1-RACK1-PP2A complex
GO:0030496--C:midbody
GO:0005739--C:mitochondrion
GO:0043025--C:neuronal cell body
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0001891--C:phagocytic cup
GO:0008656--F:cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0008200--F:ion channel inhibitor activity
GO:0030292--F:protein tyrosine kinase inhibitor activity
GO:0003723--F:RNA binding
GO:0035591--F:signaling adaptor activity
GO:0071333--P:cellular response to glucose stimulus
GO:0071363--P:cellular response to growth factor stimulus
GO:0030308--P:negative regulation of cell growth
GO:0010629--P:negative regulation of gene expression
GO:1903208--P:negative regulation of hydrogen peroxide-induced neuron death
GO:0033137--P:negative regulation of peptidyl-serine phosphorylation
GO:0050765--P:negative regulation of phagocytosis
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0043473--P:pigmentation
GO:0030822--P:positive regulation of cAMP catabolic process
GO:0030335--P:positive regulation of cell migration
GO:0051343--P:positive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0042998--P:positive regulation of Golgi to plasma membrane protein transport
GO:0043547--P:positive regulation of GTPase activity
GO:2001244--P:positive regulation of intrinsic apoptotic signaling pathway
GO:0051901--P:positive regulation of mitochondrial depolarization
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032464--P:positive regulation of protein homooligomerization
GO:0001934--P:positive regulation of protein phosphorylation
GO:0051726--P:regulation of cell cycle
GO:0006412--P:translation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000096	Aegilops tauschii	65.06	3.00e-60	226.00
IUUC-Aml-001935	Ailuropoda melanoleuca	77.92	1.00e-134	472.00
IUUC-Atr-002694	Amborella trichopoda	48.56	9.00e-77	280.00
IUUC-Apl-003918	Anas platyrhynchos	75.09	1.00e-112	398.00
IUUC-Aca-004869	Anolis carolinensis	77.92	1.00e-134	472.00
IUUC-Aly-005832	Arabidopsis lyrata	46.44	9.00e-75	273.00
IUUC-Ath-007105	Arabidopsis thaliana	47.99	1.00e-76	279.00
IUUC-Ago-007720	Ashbya gossypii	56.80	3.00e-52	198.00
IUUC-Acl-008156	Aspergillus clavatus	56.73	2.00e-92	332.00
IUUC-Afl-008684	Aspergillus flavus	55.77	1.00e-91	329.00
IUUC-Afu-008867	Aspergillus fumigatus	57.37	5.00e-94	337.00
IUUC-Ani-009221	Aspergillus nidulans	57.05	1.00e-92	332.00
IUUC-Ang-009843	Aspergillus niger	56.09	6.00e-91	327.00
IUUC-Aor-010193	Aspergillus oryzae	55.77	1.00e-91	329.00
IUUC-Ate-010420	Aspergillus terreus	56.18	1.00e-79	289.00
IUUC-Ame-011199	Astyanax mexicanus	74.45	2.00e-131	461.00
IUUC-Bgr-012064	Blumeria graminis	53.21	4.00e-88	317.00
IUUC-Bta-013357	Bos taurus	77.92	1.00e-134	472.00
IUUC-Bci-013862	Botrytis cinerea	54.49	8.00e-91	326.00
IUUC-Bdi-014690	Brachypodium distachyon	44.95	3.00e-65	241.00
IUUC-Bol-016231	Brassica oleracea	48.61	9.00e-79	286.00
IUUC-Bra-017170	Brassica rapa	48.30	3.00e-79	288.00
IUUC-Cel-018335	Caenorhabditis elegans	51.88	4.00e-76	277.00
IUUC-Cja-019914	Callithrix jacchus	77.92	1.00e-134	472.00
IUUC-Cfa-020755	Canis familiaris	77.92	1.00e-134	472.00
IUUC-Cpo-022377	Cavia porcellus	77.92	8.00e-135	473.00
IUUC-Cre-022909	Chlamydomonas reinhardtii	55.87	2.00e-87	315.00
IUUC-Csa-023025	Chlorocebus sabaeus	77.92	2.00e-133	468.00
IUUC-Cin-025647	Ciona intestinalis	59.68	3.00e-98	350.00
IUUC-Csv-026027	Ciona savignyi	59.37	1.00e-95	342.00
IUUC-Cgl-026718	Colletotrichum gloeosporioides	55.83	1.00e-82	299.00
IUUC-Cne-026930	Cryptococcus neoformans	54.17	9.00e-90	323.00
IUUC-Cme-027251	Cyanidioschyzon merolae	47.44	5.00e-76	277.00
IUUC-Dre-028669	Danio rerio	74.45	7.00e-131	459.00
IUUC-Dno-029470	Dasypus novemcinctus	97.22	7.00e-103	366.00
IUUC-Dor-031098	Dipodomys ordii	71.29	2.00e-118	418.00
IUUC-Dse-031255	Dothistroma septosporum	54.49	9.00e-91	326.00
IUUC-Dme-032118	Drosophila melanogaster	59.37	5.00e-100	357.00
IUUC-Ete-033182	Echinops telfairi	76.67	2.00e-77	281.00
IUUC-Eca-033296	Equus caballus	96.40	1.00e-77	281.00
IUUC-Eeu-034771	Erinaceus europaeus	72.56	3.00e-122	431.00
IUUC-Fca-036315	Felis catus	77.92	1.00e-134	472.00
IUUC-Fox-037702	Fusarium oxysporum	55.77	1.00e-92	332.00
IUUC-Fso-038384	Fusarium solani	55.77	8.00e-93	333.00
IUUC-Gmo-039630	Gadus morhua	73.05	2.00e-123	434.00
IUUC-Ggr-039985	Gaeumannomyces graminis	55.45	9.00e-93	332.00
IUUC-Gga-040540	Gallus gallus	77.92	1.00e-134	472.00
IUUC-Gac-041316	Gasterosteus aculeatus	71.15	4.00e-122	430.00
IUUC-Gma-042872	Glycine max	48.14	5.00e-78	283.00
IUUC-Ggo-045253	Gorilla gorilla	77.92	1.00e-134	472.00
IUUC-Hsa-046809	Homo sapiens	77.92	1.00e-134	472.00
IUUC-Hvu-047683	Hordeum vulgare	45.90	2.00e-66	245.00
IUUC-Itr-048025	Ictidomys tridecemlineatus	77.92	1.00e-134	472.00
IUUC-Kpa-049214	Komagataella pastoris	59.52	5.00e-53	201.00
IUUC-Lch-049634	Latimeria chalumnae	74.76	9.00e-131	459.00
IUUC-Lpe-050762	Leersia perrieri	45.71	1.00e-65	242.00
IUUC-Loc-052163	Lepisosteus oculatus	76.03	1.00e-132	465.00
IUUC-Lma-053113	Leptosphaeria maculans	56.09	1.00e-92	332.00
IUUC-Laf-054422	Loxodonta africana	77.92	1.00e-134	472.00
IUUC-Mcc-055348	Macaca mulatta	77.92	1.00e-133	469.00
IUUC-Meu-056543	Macropus eugenii	77.92	2.00e-134	471.00
IUUC-Mor-057107	Magnaporthe oryzae	55.77	9.00e-94	336.00
IUUC-Mpo-057487	Magnaporthe poae	55.77	3.00e-93	334.00
IUUC-Mtr-058808	Medicago truncatula	48.45	1.00e-78	285.00
IUUC-Mla-058909	Melampsora laricipopulina	54.63	5.00e-90	323.00
IUUC-Mga-059387	Meleagris gallopavo	77.92	1.00e-134	472.00
IUUC-Mvi-060392	Microbotryum violaceum	51.60	1.00e-85	309.00
IUUC-Mmr-061141	Microcebus murinus	72.57	2.00e-107	381.00
IUUC-Mdo-062932	Monodelphis domestica	77.92	1.00e-134	472.00
IUUC-Mmu-064132	Mus musculus	77.92	1.00e-134	472.00
IUUC-Mac-065422	Musa acuminata	42.37	2.00e-53	202.00
IUUC-Mpu-066721	Mustela putorius furo	76.97	4.00e-131	460.00
IUUC-Mlu-068221	Myotis lucifugus	77.92	1.00e-133	468.00
IUUC-Nfi-068344	Neosartorya fischeri	57.37	6.00e-94	337.00
IUUC-Ncr-068722	Neurospora crassa	55.13	5.00e-91	327.00
IUUC-Nle-069865	Nomascus leucogenys	77.92	6.00e-134	470.00
IUUC-Opr-071100	Ochotona princeps	63.09	1.00e-98	352.00
IUUC-Ont-072287	Oreochromis niloticus	74.13	6.00e-130	456.00
IUUC-Oan-072788	Ornithorhynchus anatinus	77.92	1.00e-134	472.00
IUUC-Ocu-073844	Oryctolagus cuniculus	75.39	6.00e-128	449.00
IUUC-Oba-075981	Oryza barthii	65.85	2.00e-60	225.00
IUUC-Obr-076099	Oryza brachyantha	44.34	4.00e-64	238.00
IUUC-Ogl-077804	Oryza glaberrima	44.95	3.00e-66	244.00
IUUC-Ogu-078682	Oryza glumaepatula	65.85	3.00e-61	228.00
IUUC-Oin-079327	Oryza indica	46.15	8.00e-66	243.00
IUUC-Olo-081084	Oryza longistaminata	46.15	8.00e-66	243.00
IUUC-Ome-081366	Oryza meridionalis	45.26	1.00e-66	246.00
IUUC-Oni-082682	Oryza nivara	45.26	1.00e-66	246.00
IUUC-Opu-084010	Oryza punctata	44.95	8.00e-67	246.00
IUUC-Oru-084358	Oryza rufipogon	45.26	1.00e-66	246.00
IUUC-Osa-085296	Oryza sativa	45.26	1.00e-66	246.00
IUUC-Ola-086400	Oryzias latipes	73.82	2.00e-129	454.00
IUUC-Olu-087817	Ostreococcus lucimarinus	55.35	5.00e-91	327.00
IUUC-Oga-088811	Otolemur garnettii	77.92	1.00e-134	472.00
IUUC-Oar-089962	Ovis aries	77.92	1.00e-134	472.00
IUUC-Ptr-091340	Pan troglodytes	77.92	1.00e-134	472.00
IUUC-Pan-091946	Papio anubis	77.92	1.00e-133	469.00
IUUC-Pma-094535	Petromyzon marinus	73.19	4.00e-128	450.00
IUUC-Pno-095100	Phaeosphaeria nodorum	50.47	1.00e-50	192.00
IUUC-Ppa-095752	Physcomitrella patens	54.95	5.00e-89	320.00
IUUC-Pfo-097311	Poecilia formosa	73.82	2.00e-129	454.00
IUUC-Pab-097863	Pongo abelii	77.92	2.00e-134	471.00
IUUC-Pop-099345	Populus trichocarpa	50.15	6.00e-81	293.00
IUUC-Pca-100594	Procavia capensis	77.92	5.00e-134	470.00
IUUC-Ppe-101743	Prunus persica	47.53	5.00e-76	277.00
IUUC-Pva-102746	Pteropus vampyrus	98.28	9.00e-97	346.00
IUUC-Pgr-103375	Puccinia graminis	74.69	5.00e-69	253.00
IUUC-Ptt-103839	Puccinia triticina	54.95	6.00e-89	320.00
IUUC-Pte-104026	Pyrenophora teres	56.09	1.00e-92	332.00
IUUC-Pyt-104584	Pyrenophora triticirepentis	56.09	1.00e-92	332.00
IUUC-Rno-104964	Rattus norvegicus	77.92	1.00e-134	472.00
IUUC-Sce-106224	Saccharomyces cerevisiae	52.94	3.00e-48	185.00
IUUC-Sha-107409	Sarcophilus harrisii	77.92	1.00e-134	472.00
IUUC-Sja-107971	Schizosaccharomyces japonicus	51.12	2.00e-84	305.00
IUUC-Spo-108297	Schizosaccharomyces pombe	49.52	2.00e-81	295.00
IUUC-Ssl-108479	Sclerotinia sclerotiorum	54.49	8.00e-91	326.00
IUUC-Smo-109017	Selaginella moellendorffii	50.32	8.00e-80	290.00
IUUC-Sit-110060	Setaria italica	45.23	1.00e-67	249.00
IUUC-Sly-111496	Solanum lycopersicum	50.31	2.00e-79	289.00
IUUC-Stu-112757	Solanum tuberosum	49.06	1.00e-75	276.00
IUUC-Sar-113173	Sorex araneus	77.92	1.00e-134	472.00
IUUC-Sbi-114681	Sorghum bicolor	45.54	4.00e-68	251.00
IUUC-Sre-115107	Sporisorium reilianum	53.21	5.00e-90	323.00
IUUC-Ssc-116218	Sus scrofa	73.50	1.00e-126	445.00
IUUC-Tru-118202	Takifugu rubripes	72.56	5.00e-127	446.00
IUUC-Tni-120260	Tetraodon nigroviridis	73.19	6.00e-127	446.00
IUUC-Tca-120951	Theobroma cacao	48.45	3.00e-80	291.00
IUUC-Tre-121961	Trichoderma reesei	56.09	6.00e-94	337.00
IUUC-Tvi-122447	Trichoderma virens	55.77	7.00e-93	333.00
IUUC-Tae-125375	Triticum aestivum	45.29	1.00e-65	243.00
IUUC-Tur-126335	Triticum urartu	65.06	3.00e-60	224.00
IUUC-Tme-127105	Tuber melanosporum	51.78	6.00e-80	290.00
IUUC-Tbe-128021	Tupaia belangeri	99.30	5.00e-81	293.00
IUUC-Ttr-128637	Tursiops truncatus	66.25	5.00e-108	384.00
IUUC-Uma-129634	Ustilago maydis	53.53	1.00e-90	325.00
IUUC-Vda-129923	Verticillium dahliae	55.77	3.00e-92	331.00
IUUC-Vpa-130410	Vicugna pacos	95.90	8.00e-69	253.00
IUUC-Vvi-131115	Vitis vinifera	48.46	2.00e-79	288.00
IUUC-Xtr-132105	Xenopus tropicalis	75.08	7.00e-132	462.00
IUUC-Xma-133875	Xiphophorus maculatus	73.82	1.00e-129	455.00
IUUC-Yli-134624	Yarrowia lipolytica	46.73	1.00e-77	282.00
IUUC-Zma-134711	Zea mays	45.54	2.00e-66	245.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence