iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066211

Ensembl Protein ID

ENSMPUP00000013417.1

UniProt Accession

M3YQ09; M3YQ09_MUSPF

Genbank Protein ID

ENSMPUP00000013417

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01066093

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000013519.1	ENSMPUT00000013632.1	ENSMPUP00000013417.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.60e-06	26.0	193	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCle +   ++++v pC H fh++C+  w        ++ +CP Cr
   Q: 193  CAICLEKYidGEELRVIPCTHRFHRKCVDPW------LLQHHTCPHCR 234
           ********66334******************......9999******8 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MHPLGLCNNN DEEDLYEYGW VGVVKLEQPE LDPKPCLTVL GKAKRAVQRG ATAVIFDVSE 60
NPEAIDQLNQ GSEDPLKRPV VYVKGADAIK LMNIVNKQKV ARARIQHRPP RQPTEYFDMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAAGACACA CTTACAGGGT GGGTCTAGAA CCTCTGAGTC CTGTGTGTTG AAGCTTTCTT 60
TCTGTCTGCC TCCTAGATGC ACCCACTGGG CCTGTGTAAT AACAACGATG AAGAGGACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	86.88	0.00e+00	1288.00
IUUC-Apl-004188	Anas platyrhynchos	71.92	0.00e+00	1018.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	3.00e-15	73.90
IUUC-Ame-011764	Astyanax mexicanus	62.90	0.00e+00	726.00
IUUC-Bta-012478	Bos taurus	66.30	0.00e+00	684.00
IUUC-Bdi-014078	Brachypodium distachyon	62.79	2.00e-12	65.50
IUUC-Cja-019504	Callithrix jacchus	85.87	0.00e+00	1295.00
IUUC-Cfa-020048	Canis familiaris	88.82	0.00e+00	1347.00
IUUC-Cpo-021725	Cavia porcellus	80.12	0.00e+00	1175.00
IUUC-Csa-023586	Chlorocebus sabaeus	86.45	0.00e+00	1238.00
IUUC-Cho-024867	Choloepus hoffmanni	90.18	0.00e+00	671.00
IUUC-Cin-025569	Ciona intestinalis	47.11	2.00e-55	210.00
IUUC-Csv-025869	Ciona savignyi	45.04	5.00e-49	189.00
IUUC-Dre-027553	Danio rerio	64.64	0.00e+00	798.00
IUUC-Dno-029370	Dasypus novemcinctus	82.34	0.00e+00	1179.00
IUUC-Dor-030816	Dipodomys ordii	77.51	0.00e+00	1088.00
IUUC-Ete-033060	Echinops telfairi	74.22	0.00e+00	845.00
IUUC-Eca-034044	Equus caballus	87.70	0.00e+00	1321.00
IUUC-Eeu-034591	Erinaceus europaeus	67.27	8.00e-143	501.00
IUUC-Fca-036000	Felis catus	89.24	0.00e+00	1365.00
IUUC-Fal-037147	Ficedula albicollis	70.18	0.00e+00	1030.00
IUUC-Gmo-039099	Gadus morhua	49.83	2.00e-115	409.00
IUUC-Gga-041243	Gallus gallus	66.39	0.00e+00	798.00
IUUC-Gac-041340	Gasterosteus aculeatus	49.06	4.00e-112	398.00
IUUC-Gma-044387	Glycine max	50.00	9.00e-15	73.60
IUUC-Ggo-044953	Gorilla gorilla	86.79	0.00e+00	1275.00
IUUC-Hsa-046484	Homo sapiens	86.89	0.00e+00	1286.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	83.29	0.00e+00	1225.00
IUUC-Lch-050004	Latimeria chalumnae	58.62	0.00e+00	652.00
IUUC-Loc-051830	Lepisosteus oculatus	66.36	0.00e+00	776.00
IUUC-Laf-053975	Loxodonta africana	82.05	0.00e+00	1187.00
IUUC-Mcc-055302	Macaca mulatta	85.39	0.00e+00	1222.00
IUUC-Meu-056263	Macropus eugenii	74.88	0.00e+00	779.00
IUUC-Mtr-058744	Medicago truncatula	54.17	2.00e-13	68.20
IUUC-Mga-059706	Meleagris gallopavo	70.04	0.00e+00	1035.00
IUUC-Mmr-061372	Microcebus murinus	84.32	0.00e+00	1188.00
IUUC-Mdo-062651	Monodelphis domestica	64.65	0.00e+00	835.00
IUUC-Mmu-064339	Mus musculus	81.17	0.00e+00	1184.00
IUUC-Mac-065356	Musa acuminata	46.75	9.00e-13	67.80
IUUC-Mlu-067058	Myotis lucifugus	88.03	0.00e+00	1258.00
IUUC-Nle-069886	Nomascus leucogenys	86.52	0.00e+00	1251.00
IUUC-Opr-070218	Ochotona princeps	78.47	0.00e+00	1044.00
IUUC-Ont-072483	Oreochromis niloticus	60.87	0.00e+00	760.00
IUUC-Oan-073718	Ornithorhynchus anatinus	71.72	0.00e+00	900.00
IUUC-Ocu-073847	Oryctolagus cuniculus	77.90	0.00e+00	1013.00
IUUC-Oba-075528	Oryza barthii	43.64	5.00e-12	65.50
IUUC-Opu-083306	Oryza punctata	67.44	9.00e-13	66.60
IUUC-Oru-084953	Oryza rufipogon	53.06	3.00e-11	62.40
IUUC-Osa-085734	Oryza sativa	53.06	3.00e-11	62.40
IUUC-Ola-087358	Oryzias latipes	61.19	0.00e+00	764.00
IUUC-Oga-088362	Otolemur garnettii	83.03	0.00e+00	1266.00
IUUC-Oar-090197	Ovis aries	99.49	1.00e-96	347.00
IUUC-Ptr-091350	Pan troglodytes	86.65	0.00e+00	1283.00
IUUC-Pan-091700	Papio anubis	85.39	0.00e+00	1218.00
IUUC-Psi-093301	Pelodiscus sinensis	70.37	0.00e+00	959.00
IUUC-Pfo-096917	Poecilia formosa	61.57	0.00e+00	753.00
IUUC-Pab-097932	Pongo abelii	86.58	0.00e+00	1305.00
IUUC-Pop-099640	Populus trichocarpa	57.14	2.00e-14	72.40
IUUC-Pca-101054	Procavia capensis	89.90	0.00e+00	937.00
IUUC-Pva-102879	Pteropus vampyrus	87.29	0.00e+00	1313.00
IUUC-Pgr-103476	Puccinia graminis	41.27	4.00e-09	55.50
IUUC-Sha-106507	Sarcophilus harrisii	52.98	3.00e-158	551.00
IUUC-Sit-110656	Setaria italica	67.44	7.00e-13	66.60
IUUC-Stu-112500	Solanum tuberosum	62.79	8.00e-13	66.60
IUUC-Sar-113182	Sorex araneus	82.69	3.00e-112	399.00
IUUC-Sbi-114414	Sorghum bicolor	40.00	1.00e-12	65.50
IUUC-Ssc-115966	Sus scrofa	82.65	0.00e+00	1068.00
IUUC-Tgu-116864	Taeniopygia guttata	62.44	0.00e+00	662.00
IUUC-Tru-118502	Takifugu rubripes	60.26	0.00e+00	719.00
IUUC-Tsy-119210	Tarsius syrichta	83.73	0.00e+00	1230.00
IUUC-Tni-120344	Tetraodon nigroviridis	51.76	6.00e-119	421.00
IUUC-Tca-120966	Theobroma cacao	46.88	4.00e-13	68.90
IUUC-Tbe-127735	Tupaia belangeri	80.78	4.00e-128	452.00
IUUC-Ttr-128714	Tursiops truncatus	75.24	0.00e+00	1020.00
IUUC-Xtr-132280	Xenopus tropicalis	59.74	0.00e+00	686.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence