iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034390

UUCD1 version

UUC-EqC-00304

Ensembl Protein ID

ENSECAP00000018610.1

UniProt Accession

F6URN2; F6URN2_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021066.1	ENSECAT00000022513.1	ENSECAP00000018610.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.30e-21	76.9	66	131
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.80e-07	28.6	167	195

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dvi++v+g+ef++h++vL+a+Ss+F+a+f ++ +es+ +  vei+++ +e+++ +l+++Ytgk+++
   Q: 66   TDVIICVEGKEFPCHRAVLSACSSYFRAMFCNDHKESR-EMLVEINGILAEAMECFLQYVYTGKVKI 131
           7************************************9.999**********************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 3    NclgilrfAdlydcpdLkdaaldfilkhF 31
           Nclgi rfAd++++  L  ++ +f+l+ F
   Q: 167  NCLGIQRFADTHSLKTLFTKCKNFALQTF 195
           *************************9977 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MVLILGRRLN REDLGVRDSP ATKRKVFEMD PKSLTGREFF DFSSGSSHAE NILQIFNEFR 60
DSRLFTDVII CVEGKEFPCH RAVLSACSSY FRAMFCNDHK ESREMLVEIN GILAEAMECF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCAGGGGT CGCTGACGCT CAGTGTTTTG GCCCCGACGG TCACATGTTT CCTTTGTTGT 60
GAGCTGCGGC AGAAACTGGT GGCCCGAGGA GACGCCGGCG CTGGAGAGAG CGCTGCGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030596--KLHL24
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:2000312--P:regulation of kainate selective glutamate receptor activity

KEGG

ecb:100058815

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001447	Ailuropoda melanoleuca	99.34	0.00e+00	1210.00
IUUC-Apl-003919	Anas platyrhynchos	55.21	0.00e+00	644.00
IUUC-Aca-004821	Anolis carolinensis	94.50	0.00e+00	1160.00
IUUC-Ame-010778	Astyanax mexicanus	84.47	0.00e+00	1088.00
IUUC-Bta-012622	Bos taurus	99.50	0.00e+00	1211.00
IUUC-Cja-018938	Callithrix jacchus	99.33	0.00e+00	1212.00
IUUC-Cfa-020831	Canis familiaris	99.67	0.00e+00	1215.00
IUUC-Cpo-021569	Cavia porcellus	98.67	0.00e+00	1204.00
IUUC-Csa-024070	Chlorocebus sabaeus	99.50	0.00e+00	1214.00
IUUC-Cin-025465	Ciona intestinalis	53.12	0.00e+00	646.00
IUUC-Csv-025878	Ciona savignyi	54.01	0.00e+00	635.00
IUUC-Dre-028103	Danio rerio	84.78	0.00e+00	1085.00
IUUC-Dno-029374	Dasypus novemcinctus	98.67	0.00e+00	1203.00
IUUC-Dor-030922	Dipodomys ordii	86.01	3.00e-143	501.00
IUUC-Dse-031370	Dothistroma septosporum	36.36	1.00e-05	43.10
IUUC-Ete-032909	Echinops telfairi	97.50	0.00e+00	1178.00
IUUC-Fca-036449	Felis catus	99.83	0.00e+00	1217.00
IUUC-Fal-036612	Ficedula albicollis	96.50	0.00e+00	1182.00
IUUC-Gmo-038760	Gadus morhua	81.14	0.00e+00	1033.00
IUUC-Gga-040779	Gallus gallus	96.48	0.00e+00	743.00
IUUC-Gac-042145	Gasterosteus aculeatus	82.38	0.00e+00	1058.00
IUUC-Ggo-045506	Gorilla gorilla	99.00	0.00e+00	1206.00
IUUC-Hsa-046510	Homo sapiens	99.50	0.00e+00	1214.00
IUUC-Itr-048255	Ictidomys tridecemlineatus	98.84	0.00e+00	1204.00
IUUC-Lch-049594	Latimeria chalumnae	86.74	0.00e+00	1097.00
IUUC-Loc-052147	Lepisosteus oculatus	86.12	0.00e+00	1084.00
IUUC-Laf-054224	Loxodonta africana	98.84	0.00e+00	1204.00
IUUC-Meu-056366	Macropus eugenii	96.74	2.00e-157	549.00
IUUC-Mga-059535	Meleagris gallopavo	96.33	0.00e+00	1165.00
IUUC-Mdo-063082	Monodelphis domestica	96.67	0.00e+00	1181.00
IUUC-Mmu-063152	Mus musculus	98.83	0.00e+00	1209.00
IUUC-Mpu-065928	Mustela putorius furo	99.67	0.00e+00	1215.00
IUUC-Mlu-068041	Myotis lucifugus	98.67	0.00e+00	1203.00
IUUC-Nle-069293	Nomascus leucogenys	99.50	0.00e+00	1214.00
IUUC-Opr-070368	Ochotona princeps	99.00	0.00e+00	1208.00
IUUC-Ont-071571	Oreochromis niloticus	81.97	0.00e+00	1032.00
IUUC-Oan-072849	Ornithorhynchus anatinus	97.17	0.00e+00	1189.00
IUUC-Ocu-073987	Oryctolagus cuniculus	98.84	0.00e+00	1204.00
IUUC-Ola-087513	Oryzias latipes	81.30	0.00e+00	1053.00
IUUC-Oga-088595	Otolemur garnettii	99.00	0.00e+00	1206.00
IUUC-Oar-089935	Ovis aries	99.50	0.00e+00	1211.00
IUUC-Ptr-091664	Pan troglodytes	99.17	0.00e+00	1203.00
IUUC-Pan-091881	Papio anubis	99.17	0.00e+00	1208.00
IUUC-Psi-092983	Pelodiscus sinensis	96.17	0.00e+00	1178.00
IUUC-Pfo-096218	Poecilia formosa	76.68	0.00e+00	982.00
IUUC-Pab-098487	Pongo abelii	99.50	0.00e+00	1214.00
IUUC-Pca-100916	Procavia capensis	98.17	0.00e+00	1198.00
IUUC-Pva-103010	Pteropus vampyrus	99.67	0.00e+00	1215.00
IUUC-Rno-105025	Rattus norvegicus	98.50	0.00e+00	1200.00
IUUC-Sha-106793	Sarcophilus harrisii	97.33	0.00e+00	1185.00
IUUC-Sar-113290	Sorex araneus	88.50	0.00e+00	1076.00
IUUC-Ssc-115631	Sus scrofa	99.50	0.00e+00	1212.00
IUUC-Tgu-116856	Taeniopygia guttata	96.67	0.00e+00	1185.00
IUUC-Tru-118210	Takifugu rubripes	82.17	0.00e+00	1031.00
IUUC-Tsy-118964	Tarsius syrichta	99.02	0.00e+00	628.00
IUUC-Tni-120462	Tetraodon nigroviridis	81.88	0.00e+00	1022.00
IUUC-Tbe-128114	Tupaia belangeri	98.69	3.00e-178	618.00
IUUC-Ttr-128565	Tursiops truncatus	99.50	0.00e+00	1214.00
IUUC-Vpa-130093	Vicugna pacos	89.67	0.00e+00	1071.00
IUUC-Xtr-132233	Xenopus tropicalis	90.33	0.00e+00	1122.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence