iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-042332

Ensembl Protein ID

ENSGACP00000014999.1

UniProt Accession

G3PBM5; G3PBM5_GASAC

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000011349.1	ENSGACT00000015028.1	ENSGACP00000014999.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.40e-13	48.5	89	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ +lydye+ +  +L+++kG+ ++++  ++++++W+ + + ++g +G +P+n+v+ 
   Q: 89   TFVALYDYESRTASDLSFRKGERLQIV--NNTEGDWWLARSLTTGESGYIPSNYVAP 143
           5789***********************..8999*********************975 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MGGSKSKPKD VGQRTRSLEG NLSSGGGVGG HLLSANQQSL TPNRSPTMEG GLGGNQPMTN 60
NAEMTLFGGV DNNTVTSPSR ITLAGGVTTF VALYDYESRT ASDLSFRKGE RLQIVNNTEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTGATTTCG GTGTGTTCCG GCACAGACGC CGACGGCCCG GGAGAAGGTC TCCGTGCGCG 60
ACTGGGCGTT CCGGCGTACT TTACTTTTTT TTTTTTTTAA TTCGATTCAT TCATACGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001713	Ailuropoda melanoleuca	80.59	0.00e+00	901.00
IUUC-Aca-004237	Anolis carolinensis	81.48	0.00e+00	905.00
IUUC-Bta-012982	Bos taurus	81.37	0.00e+00	902.00
IUUC-Cja-019995	Callithrix jacchus	80.59	0.00e+00	901.00
IUUC-Cfa-020060	Canis familiaris	81.67	0.00e+00	910.00
IUUC-Cpo-021557	Cavia porcellus	81.45	0.00e+00	902.00
IUUC-Csa-023711	Chlorocebus sabaeus	80.59	0.00e+00	899.00
IUUC-Cin-025390	Ciona intestinalis	69.51	0.00e+00	665.00
IUUC-Csv-026029	Ciona savignyi	62.76	0.00e+00	635.00
IUUC-Dre-028491	Danio rerio	88.13	0.00e+00	966.00
IUUC-Dno-029651	Dasypus novemcinctus	78.74	0.00e+00	885.00
IUUC-Eca-033970	Equus caballus	78.15	0.00e+00	871.00
IUUC-Fca-036113	Felis catus	81.67	0.00e+00	910.00
IUUC-Fal-036785	Ficedula albicollis	80.95	0.00e+00	903.00
IUUC-Gga-040899	Gallus gallus	81.30	0.00e+00	905.00
IUUC-Hsa-046192	Homo sapiens	80.59	0.00e+00	898.00
IUUC-Itr-049014	Ictidomys tridecemlineatus	80.40	0.00e+00	895.00
IUUC-Lch-049892	Latimeria chalumnae	80.86	0.00e+00	907.00
IUUC-Loc-052812	Lepisosteus oculatus	87.16	0.00e+00	969.00
IUUC-Laf-053977	Loxodonta africana	80.95	0.00e+00	908.00
IUUC-Mcc-055159	Macaca mulatta	78.99	0.00e+00	894.00
IUUC-Mga-060135	Meleagris gallopavo	80.22	0.00e+00	897.00
IUUC-Mmr-061168	Microcebus murinus	78.96	0.00e+00	899.00
IUUC-Mdo-063030	Monodelphis domestica	79.53	0.00e+00	898.00
IUUC-Mmu-063893	Mus musculus	80.22	0.00e+00	898.00
IUUC-Mac-064539	Musa acuminata	30.69	3.00e-19	90.50
IUUC-Mpu-066411	Mustela putorius furo	81.67	0.00e+00	910.00
IUUC-Mlu-068139	Myotis lucifugus	80.22	0.00e+00	894.00
IUUC-Nle-070178	Nomascus leucogenys	79.30	0.00e+00	860.00
IUUC-Ont-072666	Oreochromis niloticus	92.55	0.00e+00	986.00
IUUC-Ocu-074403	Oryctolagus cuniculus	80.29	0.00e+00	894.00
IUUC-Ola-086953	Oryzias latipes	91.34	0.00e+00	1000.00
IUUC-Oga-088493	Otolemur garnettii	80.40	0.00e+00	897.00
IUUC-Oar-090279	Ovis aries	81.33	0.00e+00	901.00
IUUC-Ptr-091050	Pan troglodytes	80.59	0.00e+00	898.00
IUUC-Pan-091862	Papio anubis	81.48	0.00e+00	905.00
IUUC-Psi-093071	Pelodiscus sinensis	81.11	0.00e+00	905.00
IUUC-Pab-097902	Pongo abelii	78.99	0.00e+00	893.00
IUUC-Pop-099554	Populus trichocarpa	32.59	1.00e-23	105.00
IUUC-Rno-105847	Rattus norvegicus	80.15	0.00e+00	899.00
IUUC-Sha-107539	Sarcophilus harrisii	81.48	0.00e+00	907.00
IUUC-Ssc-115762	Sus scrofa	80.47	0.00e+00	894.00
IUUC-Tru-117849	Takifugu rubripes	92.65	0.00e+00	994.00
IUUC-Ttr-128702	Tursiops truncatus	75.46	0.00e+00	825.00
IUUC-Vvi-131181	Vitis vinifera	32.31	1.00e-21	98.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence