iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072493

Ensembl Protein ID

ENSONIP00000026363.1

UniProt Accession

I3KZ16; I3KZ16_ORENI

Genbank Protein ID

ENSONIP00000026363

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01004908

Gene Name

hic1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000021060.1	ENSONIT00000026386.1	ENSONIP00000026363.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.40e-13	50.7	28	90

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgklden 68
           +Dvi+vv++  f+ahk +LaasS ++++l  +        + ++++ + v+p+vfr++l+++Ytg+l+e 
   Q: 28   CDVIIVVQNALFRAHKNILAASSLYLKSLVVH-------DNLINLDhEmVSPGVFRVILDYIYTGRLSEG 90
           9*****************************66.......5789999549******************985 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MLDAMEVPSH ARDLLLQLNS QRTKGFLCDV IIVVQNALFR AHKNILAASS LYLKSLVVHD 60
NLINLDHEMV SPGVFRVILD YIYTGRLSEG DPTSPNEPNL GAVLAAASYL QLLDLVALCK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGGATG CCATGGAAGT TCCAAGTCAT GCTAGGGATC TCCTCCTGCA GCTCAACAGC 60
CAACGCACCA AGGGCTTCCT GTGTGATGTT ATCATTGTGG TGCAGAACGC CCTCTTCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR028424--HIC1
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005622--C:intracellular
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	65.40	8.00e-78	285.00
IUUC-Aca-004680	Anolis carolinensis	80.30	2.00e-64	240.00
IUUC-Ame-010967	Astyanax mexicanus	71.13	0.00e+00	877.00
IUUC-Bta-013567	Bos taurus	66.52	4.00e-78	286.00
IUUC-Cja-019621	Callithrix jacchus	83.33	7.00e-39	152.00
IUUC-Cfa-020731	Canis familiaris	65.97	4.00e-80	292.00
IUUC-Cpo-021326	Cavia porcellus	66.53	7.00e-84	305.00
IUUC-Csa-023645	Chlorocebus sabaeus	65.69	3.00e-80	293.00
IUUC-Dre-028027	Danio rerio	65.21	0.00e+00	770.00
IUUC-Dno-028900	Dasypus novemcinctus	66.52	2.00e-82	300.00
IUUC-Fal-036980	Ficedula albicollis	54.57	6.00e-110	391.00
IUUC-Gga-040708	Gallus gallus	51.75	4.00e-173	601.00
IUUC-Gac-041742	Gasterosteus aculeatus	83.15	0.00e+00	969.00
IUUC-Ggo-044591	Gorilla gorilla	66.52	6.00e-79	288.00
IUUC-Hsa-046769	Homo sapiens	66.52	1.00e-78	288.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	65.97	6.00e-80	292.00
IUUC-Lch-049412	Latimeria chalumnae	54.52	0.00e+00	665.00
IUUC-Loc-051883	Lepisosteus oculatus	72.50	6.00e-132	464.00
IUUC-Laf-053358	Loxodonta africana	65.69	3.00e-80	292.00
IUUC-Mcc-054981	Macaca mulatta	65.69	3.00e-80	293.00
IUUC-Meu-056181	Macropus eugenii	53.57	1.00e-52	200.00
IUUC-Mga-059592	Meleagris gallopavo	64.69	2.00e-106	379.00
IUUC-Mmr-061560	Microcebus murinus	66.52	3.00e-82	299.00
IUUC-Mmu-064258	Mus musculus	57.10	2.00e-92	334.00
IUUC-Mpu-065911	Mustela putorius furo	65.97	4.00e-80	292.00
IUUC-Ola-086584	Oryzias latipes	79.89	0.00e+00	934.00
IUUC-Oga-088774	Otolemur garnettii	66.09	3.00e-78	286.00
IUUC-Ptr-090491	Pan troglodytes	65.97	6.00e-81	294.00
IUUC-Pma-094179	Petromyzon marinus	73.08	2.00e-32	129.00
IUUC-Pfo-096282	Poecilia formosa	86.68	0.00e+00	1113.00
IUUC-Pab-098488	Pongo abelii	66.52	7.00e-79	288.00
IUUC-Pca-100667	Procavia capensis	65.67	3.00e-82	299.00
IUUC-Pva-102421	Pteropus vampyrus	65.55	3.00e-84	306.00
IUUC-Rno-105528	Rattus norvegicus	66.96	3.00e-76	280.00
IUUC-Sar-113478	Sorex araneus	65.55	3.00e-80	293.00
IUUC-Ssc-115420	Sus scrofa	57.91	3.00e-97	349.00
IUUC-Tgu-116642	Taeniopygia guttata	53.96	3.00e-109	389.00
IUUC-Tru-118583	Takifugu rubripes	80.82	0.00e+00	997.00
IUUC-Xtr-132210	Xenopus tropicalis	53.91	0.00e+00	634.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence