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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063718
UUCD1 version UUC-MuM-00687
Ensembl Protein ID ENSMUSP00000022623.6
UniProt Accession A0A0R4J031; A0A0R4J031_MOUSE
Genbank Protein ID EDL35999.1
Protein Name Tripartite motif-containing 35; Tripartite motif-containing protein 35
Genbank Nucleotide ID AC140329
Gene Name Trim35; mCG_2507
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000022043.18 ENSMUST00000022623.12 ENSMUSP00000022623.6
ENSMUSG00000022043.18 ENSMUST00000121006.1 ENSMUSP00000112877.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
HINT
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 1.30e-07 32.6 31 99
E3 activity/RING/RING 1.40e-06 29.9 36 76
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawce 70
            ee+lC++ ++++rd v+l +G+ + r+++  + + + + +cPv++++  + +l  n+tl +l++  + 
   Q: 31   KEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTpSCPVCKERAVPGELRTNHTLNNLVETLLR 99
           689******************************9888888**********************9987665 PP
   

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+C+++f+d  ++l+CgH f++ C+  +w     + +++ +CP+C+
   Q: 36   CAVCYDPFRD-AVTLRCGHNFCRRCVsGCW-----EVQTTPSCPVCK 76
           ********99.999************9999.....79999******7 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MKAATPVVVT AAAPAMEPGP SVSPGPSRSF KEELLCAVCY DPFRDAVTLR CGHNFCRRCV 60
SGCWEVQTTP SCPVCKERAV PGELRTNHTL NNLVETLLRE EAEGARWTGR RSPRPCRAHR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063718|E3,U-box;E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCCCAGATCT TCAGCAGGGA CAACGCCCGC AGGCTAGGCA TGAAGGCGGC GACACCGGTG 60
GTGGTGACGG CGGCTGCTCC TGCGATGGAG CCGGGCCCTT CTGTGTCCCC GGGGCCTTCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063718|E3,U-box;E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX
PRINTS

PR01407--BUTYPHLNCDUF
SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY
Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process
KEGG mmu:66854
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001788 Ailuropoda melanoleuca 80.00 0.00e+00 852.00
IUUC-Apl-003958 Anas platyrhynchos 49.49 8.00e-122 430.00
IUUC-Aca-005199 Anolis carolinensis 42.72 8.00e-116 410.00
IUUC-Bta-013359 Bos taurus 78.07 0.00e+00 810.00
IUUC-Cja-018900 Callithrix jacchus 69.04 0.00e+00 721.00
IUUC-Cfa-020685 Canis familiaris 80.20 0.00e+00 857.00
IUUC-Cpo-022253 Cavia porcellus 73.00 0.00e+00 727.00
IUUC-Csa-023777 Chlorocebus sabaeus 80.60 0.00e+00 852.00
IUUC-Dno-029065 Dasypus novemcinctus 75.29 0.00e+00 813.00
IUUC-Dor-030248 Dipodomys ordii 59.04 9.00e-95 339.00
IUUC-Ete-033183 Echinops telfairi 68.00 0.00e+00 677.00
IUUC-Eca-033263 Equus caballus 77.61 0.00e+00 728.00
IUUC-Eeu-034699 Erinaceus europaeus 73.58 1.00e-107 383.00
IUUC-Fca-036366 Felis catus 79.20 0.00e+00 843.00
IUUC-Fal-037257 Ficedula albicollis 52.57 5.00e-145 507.00
IUUC-Gmo-038512 Gadus morhua 35.17 1.00e-65 244.00
IUUC-Gga-041125 Gallus gallus 49.86 1.00e-98 352.00
IUUC-Ggo-045233 Gorilla gorilla 79.88 5.00e-157 546.00
IUUC-Hsa-046042 Homo sapiens 80.60 0.00e+00 853.00
IUUC-Itr-048751 Ictidomys tridecemlineatus 78.32 0.00e+00 816.00
IUUC-Laf-054322 Loxodonta africana 79.84 0.00e+00 827.00
IUUC-Mcc-055555 Macaca mulatta 78.66 0.00e+00 833.00
IUUC-Meu-055900 Macropus eugenii 71.07 0.00e+00 729.00
IUUC-Mga-059380 Meleagris gallopavo 52.23 2.00e-98 352.00
IUUC-Mmr-061296 Microcebus murinus 78.20 0.00e+00 822.00
IUUC-Mdo-062811 Monodelphis domestica 71.14 0.00e+00 738.00
IUUC-Mpu-066219 Mustela putorius furo 79.92 0.00e+00 829.00
IUUC-Mlu-067033 Myotis lucifugus 76.40 0.00e+00 814.00
IUUC-Nle-069806 Nomascus leucogenys 80.38 0.00e+00 795.00
IUUC-Opr-070248 Ochotona princeps 71.40 0.00e+00 708.00
IUUC-Ont-072047 Oreochromis niloticus 33.06 4.00e-66 245.00
IUUC-Oan-073364 Ornithorhynchus anatinus 61.34 4.00e-93 333.00
IUUC-Ocu-074572 Oryctolagus cuniculus 80.91 0.00e+00 872.00
IUUC-Oga-088378 Otolemur garnettii 78.80 0.00e+00 822.00
IUUC-Oar-089516 Ovis aries 77.62 0.00e+00 798.00
IUUC-Ptr-091313 Pan troglodytes 80.60 0.00e+00 853.00
IUUC-Pan-092877 Papio anubis 80.80 0.00e+00 853.00
IUUC-Psi-093928 Pelodiscus sinensis 54.90 1.00e-153 536.00
IUUC-Pfo-096690 Poecilia formosa 34.09 1.00e-68 253.00
IUUC-Pab-098624 Pongo abelii 80.20 0.00e+00 845.00
IUUC-Pca-100469 Procavia capensis 72.90 0.00e+00 753.00
IUUC-Pva-103227 Pteropus vampyrus 79.80 0.00e+00 849.00
IUUC-Rno-105778 Rattus norvegicus 98.97 0.00e+00 953.00
IUUC-Sha-107392 Sarcophilus harrisii 62.38 0.00e+00 637.00
IUUC-Sar-113297 Sorex araneus 72.09 4.00e-52 197.00
IUUC-Ssc-115739 Sus scrofa 78.69 0.00e+00 812.00
IUUC-Tru-117718 Takifugu rubripes 30.31 1.00e-60 227.00
IUUC-Tbe-127926 Tupaia belangeri 76.31 2.00e-123 436.00
IUUC-Ttr-129293 Tursiops truncatus 80.20 0.00e+00 843.00
IUUC-Vpa-130379 Vicugna pacos 78.76 3.00e-143 500.00
Created Date 25-Jun-2017

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