iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088738

Ensembl Protein ID

ENSOGAP00000004316.2

UniProt Accession

H0WQR5; H0WQR5_OTOGA

Genbank Protein ID

ENSOGAP00000004316

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03015726

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000004830.2	ENSOGAT00000004832.2	ENSOGAP00000004316.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.22	0.00e+00	897.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

VKMVDTESPI CPLSPLEADD LESPLSEEFL QEMGNIQEIS QSIGEDSSGS FSFTEYQHLG 60
SGPGSDGSVI TDTLSPASSP SSVTYPVVPG STDESPSGAL NIECRICGDK ASGYHYGVHA 120

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Nucleotide Sequence
(Fasta)

GTCAAGATGG TGGACACAGA AAGCCCGATC TGTCCCCTCT CCCCGCTGGA GGCCGATGAT 60
CTGGAAAGCC CATTATCTGA GGAATTCCTA CAGGAAATGG GAAACATTCA AGAGATCTCT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	94.70	0.00e+00	928.00
IUUC-Apl-003330	Anas platyrhynchos	89.03	0.00e+00	856.00
IUUC-Aca-004598	Anolis carolinensis	85.53	0.00e+00	828.00
IUUC-Acl-008339	Aspergillus clavatus	48.48	6.10e-02	30.80
IUUC-Ame-011508	Astyanax mexicanus	72.98	0.00e+00	697.00
IUUC-Bta-012621	Bos taurus	95.32	0.00e+00	899.00
IUUC-Cja-019688	Callithrix jacchus	96.37	0.00e+00	900.00
IUUC-Cfa-020859	Canis familiaris	94.87	0.00e+00	927.00
IUUC-Cpo-021607	Cavia porcellus	87.61	0.00e+00	828.00
IUUC-Csa-023313	Chlorocebus sabaeus	96.58	0.00e+00	899.00
IUUC-Cho-024741	Choloepus hoffmanni	83.97	0.00e+00	752.00
IUUC-Cgl-026615	Colletotrichum gloeosporioides	32.76	4.00e-01	27.30
IUUC-Dre-027446	Danio rerio	71.91	0.00e+00	683.00
IUUC-Dno-029173	Dasypus novemcinctus	93.19	0.00e+00	877.00
IUUC-Dor-030581	Dipodomys ordii	91.22	0.00e+00	818.00
IUUC-Dme-031794	Drosophila melanogaster	34.07	8.00e-56	212.00
IUUC-Ete-032330	Echinops telfairi	91.03	0.00e+00	879.00
IUUC-Eca-033712	Equus caballus	95.74	0.00e+00	887.00
IUUC-Fca-036555	Felis catus	95.74	0.00e+00	932.00
IUUC-Fal-036677	Ficedula albicollis	88.89	0.00e+00	852.00
IUUC-Gmo-039240	Gadus morhua	80.48	0.00e+00	637.00
IUUC-Gga-040473	Gallus gallus	89.74	0.00e+00	860.00
IUUC-Gac-041872	Gasterosteus aculeatus	71.67	0.00e+00	702.00
IUUC-Ggo-045226	Gorilla gorilla	97.22	0.00e+00	906.00
IUUC-Hsa-046893	Homo sapiens	97.22	0.00e+00	906.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	92.95	0.00e+00	874.00
IUUC-Lch-050116	Latimeria chalumnae	80.13	0.00e+00	774.00
IUUC-Loc-052131	Lepisosteus oculatus	82.00	0.00e+00	683.00
IUUC-Laf-054323	Loxodonta africana	95.30	0.00e+00	894.00
IUUC-Mcc-054841	Macaca mulatta	97.02	0.00e+00	904.00
IUUC-Meu-056833	Macropus eugenii	82.48	0.00e+00	750.00
IUUC-Mtr-058471	Medicago truncatula	29.82	1.90e-01	30.00
IUUC-Mga-059995	Meleagris gallopavo	80.30	0.00e+00	756.00
IUUC-Mdo-061954	Monodelphis domestica	88.60	0.00e+00	784.00
IUUC-Mmu-064295	Mus musculus	91.88	0.00e+00	835.00
IUUC-Mpu-066216	Mustela putorius furo	95.09	0.00e+00	927.00
IUUC-Nle-069970	Nomascus leucogenys	97.01	0.00e+00	904.00
IUUC-Ont-071594	Oreochromis niloticus	72.30	0.00e+00	692.00
IUUC-Oan-073501	Ornithorhynchus anatinus	91.20	0.00e+00	768.00
IUUC-Ocu-074634	Oryctolagus cuniculus	84.69	0.00e+00	833.00
IUUC-Oni-082926	Oryza nivara	29.41	1.10e-02	30.80
IUUC-Ola-086585	Oryzias latipes	78.31	0.00e+00	631.00
IUUC-Oar-090453	Ovis aries	94.89	0.00e+00	896.00
IUUC-Ptr-091518	Pan troglodytes	97.01	0.00e+00	900.00
IUUC-Pan-092006	Papio anubis	97.01	0.00e+00	900.00
IUUC-Psi-093352	Pelodiscus sinensis	87.71	0.00e+00	850.00
IUUC-Pfo-096060	Poecilia formosa	71.25	0.00e+00	682.00
IUUC-Pab-098602	Pongo abelii	90.51	0.00e+00	804.00
IUUC-Pva-102175	Pteropus vampyrus	89.53	0.00e+00	865.00
IUUC-Rno-105283	Rattus norvegicus	92.09	0.00e+00	835.00
IUUC-Sce-106436	Saccharomyces cerevisiae	27.42	1.30e-02	31.20
IUUC-Sha-106560	Sarcophilus harrisii	92.32	0.00e+00	870.00
IUUC-Smo-109075	Selaginella moellendorffii	30.00	1.30e-01	29.60
IUUC-Ssc-115266	Sus scrofa	94.66	0.00e+00	932.00
IUUC-Tgu-116778	Taeniopygia guttata	88.72	0.00e+00	856.00
IUUC-Tru-118436	Takifugu rubripes	71.25	0.00e+00	692.00
IUUC-Tsy-119642	Tarsius syrichta	83.76	0.00e+00	754.00
IUUC-Tni-119859	Tetraodon nigroviridis	71.04	0.00e+00	684.00
IUUC-Tvi-122624	Trichoderma virens	31.48	7.10e-02	29.60
IUUC-Tbe-127464	Tupaia belangeri	93.80	0.00e+00	916.00
IUUC-Ttr-129307	Tursiops truncatus	91.04	0.00e+00	838.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence