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Tag Content
UUCD2 ID IUUC-Oan-072945
UUCD1 version UUC-OrA-00440
Ensembl Protein ID ENSOANP00000009850.3
UniProt Accession F7BRS4; F7BRS4_ORNAN
Protein Name Histone-lysine N-methyltransferase
Gene Name KMT2C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOANG00000006160.3 ENSOANT00000009852.3 ENSOANP00000009850.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 3.00e-32 110.8 1089 1140
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
            C+vC +++++e+ +++C++C++w+H+ C +l+ eee++n  +  + C+ Cr
   Q: 1089 TCPVCYRNYREEELILQCRQCDRWMHAICQNLNTEEEVENIADigFDCTMCR 1140
           6****************************************9999******8 PP
   
Organism Ornithorhynchus anatinus
Protein Sequence
(Fasta)
MSSEEDKSVE PPPPEEPGAP APSPAAADKR PRGRPRKDGA SPFQRARKKP RSRGKTAVED 60
EGSMDGLEAA ETENTVETEV KEQSAEEDAE TEVDSHKQLT PVLQRSVSEE SASSTASVGV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oan-072945|E3,PHD|Ornithorhynchus anatinus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNGTGGTG GATTCGTACC TGCCGCCCGG 60
ACCTGCGGGA AATGCGAGAG GCCGAGCTGA GCGGCCCCAG ACGCAGCCGG AGCCGGAGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oan-072945|E3,PHD|Ornithorhynchus anatinus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR000637--HMGI/Y_DNA-bd_CS
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS00354--HMGI_Y
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002314 Ailuropoda melanoleuca 72.86 0.00e+00 4446.00
IUUC-Atr-002455 Amborella trichopoda 35.25 8.00e-32 132.00
IUUC-Apl-003311 Anas platyrhynchos 73.10 0.00e+00 4431.00
IUUC-Aca-004705 Anolis carolinensis 65.47 0.00e+00 3935.00
IUUC-Aly-006293 Arabidopsis lyrata 36.41 5.00e-32 132.00
IUUC-Ath-006690 Arabidopsis thaliana 44.37 1.00e-30 128.00
IUUC-Ame-010612 Astyanax mexicanus 70.89 0.00e+00 890.00
IUUC-Bta-012322 Bos taurus 72.61 0.00e+00 3352.00
IUUC-Bol-016540 Brassica oleracea 36.70 7.00e-31 129.00
IUUC-Bra-017422 Brassica rapa 33.51 4.00e-28 119.00
IUUC-Cel-018354 Caenorhabditis elegans 35.67 2.00e-64 241.00
IUUC-Cja-019983 Callithrix jacchus 72.90 0.00e+00 4638.00
IUUC-Cfa-020903 Canis familiaris 71.47 0.00e+00 4424.00
IUUC-Cpo-021732 Cavia porcellus 69.01 0.00e+00 4193.00
IUUC-Cre-022891 Chlamydomonas reinhardtii 45.31 4.00e-30 127.00
IUUC-Csa-023083 Chlorocebus sabaeus 77.03 0.00e+00 6495.00
IUUC-Cho-024469 Choloepus hoffmanni 69.57 0.00e+00 1875.00
IUUC-Cme-027224 Cyanidioschyzon merolae 36.71 6.00e-12 65.90
IUUC-Dre-028110 Danio rerio 57.08 0.00e+00 1684.00
IUUC-Dor-030569 Dipodomys ordii 66.59 0.00e+00 2290.00
IUUC-Dme-031590 Drosophila melanogaster 33.54 1.00e-67 251.00
IUUC-Eca-033945 Equus caballus 74.73 0.00e+00 4387.00
IUUC-Eeu-034848 Erinaceus europaeus 39.16 2.00e-142 501.00
IUUC-Fca-035922 Felis catus 71.46 0.00e+00 4249.00
IUUC-Fal-037179 Ficedula albicollis 74.34 0.00e+00 889.00
IUUC-Gmo-039403 Gadus morhua 53.98 0.00e+00 1215.00
IUUC-Gac-041896 Gasterosteus aculeatus 45.76 0.00e+00 1872.00
IUUC-Gma-044380 Glycine max 42.51 2.00e-33 137.00
IUUC-Ggo-044812 Gorilla gorilla 70.72 0.00e+00 4379.00
IUUC-Hsa-046595 Homo sapiens 72.73 0.00e+00 4649.00
IUUC-Itr-048303 Ictidomys tridecemlineatus 71.35 0.00e+00 4291.00
IUUC-Lch-050086 Latimeria chalumnae 57.54 0.00e+00 3296.00
IUUC-Loc-052891 Lepisosteus oculatus 58.84 0.00e+00 3815.00
IUUC-Laf-054348 Loxodonta africana 73.41 0.00e+00 2662.00
IUUC-Mcc-054868 Macaca mulatta 72.94 0.00e+00 4547.00
IUUC-Meu-056322 Macropus eugenii 69.13 0.00e+00 1284.00
IUUC-Mtr-058327 Medicago truncatula 40.62 5.00e-30 126.00
IUUC-Mga-059541 Meleagris gallopavo 72.93 0.00e+00 4489.00
IUUC-Mmr-061092 Microcebus murinus 75.81 0.00e+00 6412.00
IUUC-Mdo-062610 Monodelphis domestica 77.52 0.00e+00 2184.00
IUUC-Mmu-063666 Mus musculus 70.35 0.00e+00 4274.00
IUUC-Mac-064935 Musa acuminata 33.16 1.00e-28 121.00
IUUC-Mpu-066366 Mustela putorius furo 70.97 0.00e+00 4003.00
IUUC-Mlu-068201 Myotis lucifugus 71.40 0.00e+00 3553.00
IUUC-Nle-069232 Nomascus leucogenys 76.60 0.00e+00 6397.00
IUUC-Opr-070625 Ochotona princeps 63.23 0.00e+00 1074.00
IUUC-Ont-072401 Oreochromis niloticus 53.07 0.00e+00 1168.00
IUUC-Ocu-074920 Oryctolagus cuniculus 75.53 0.00e+00 6251.00
IUUC-Oba-075647 Oryza barthii 32.91 2.00e-31 130.00
IUUC-Olo-080577 Oryza longistaminata 44.00 8.00e-30 125.00
IUUC-Ome-081214 Oryza meridionalis 32.91 2.00e-31 130.00
IUUC-Oni-083000 Oryza nivara 32.91 2.00e-31 130.00
IUUC-Opu-083842 Oryza punctata 33.76 1.00e-31 131.00
IUUC-Oru-084361 Oryza rufipogon 32.91 2.00e-31 130.00
IUUC-Ola-086436 Oryzias latipes 43.85 0.00e+00 1817.00
IUUC-Olu-087718 Ostreococcus lucimarinus 32.54 2.00e-25 111.00
IUUC-Oga-088637 Otolemur garnettii 70.75 0.00e+00 3497.00
IUUC-Oar-089363 Ovis aries 68.68 0.00e+00 3142.00
IUUC-Ptr-091527 Pan troglodytes 72.97 0.00e+00 4621.00
IUUC-Pan-092102 Papio anubis 70.05 0.00e+00 4267.00
IUUC-Pma-094252 Petromyzon marinus 42.66 5.00e-166 578.00
IUUC-Ppa-095221 Physcomitrella patens 32.30 8.00e-28 118.00
IUUC-Pfo-096288 Poecilia formosa 48.24 0.00e+00 1486.00
IUUC-Pab-098241 Pongo abelii 70.63 0.00e+00 2325.00
IUUC-Pop-099585 Populus trichocarpa 31.94 3.00e-26 113.00
IUUC-Pca-100103 Procavia capensis 91.29 0.00e+00 1384.00
IUUC-Ppe-101920 Prunus persica 32.14 2.00e-25 110.00
IUUC-Pva-102238 Pteropus vampyrus 69.45 0.00e+00 2201.00
IUUC-Sha-106550 Sarcophilus harrisii 78.10 0.00e+00 6456.00
IUUC-Smo-109164 Selaginella moellendorffii 38.06 9.00e-27 115.00
IUUC-Sly-111158 Solanum lycopersicum 35.98 1.00e-30 128.00
IUUC-Stu-112529 Solanum tuberosum 38.46 4.00e-33 135.00
IUUC-Sar-113183 Sorex araneus 62.91 0.00e+00 644.00
IUUC-Tgu-116677 Taeniopygia guttata 72.24 0.00e+00 3396.00
IUUC-Tru-118037 Takifugu rubripes 47.89 0.00e+00 1454.00
IUUC-Tsy-118932 Tarsius syrichta 72.70 0.00e+00 2773.00
IUUC-Tni-119970 Tetraodon nigroviridis 47.11 0.00e+00 1409.00
IUUC-Tca-121624 Theobroma cacao 32.46 6.00e-26 112.00
IUUC-Ttr-129051 Tursiops truncatus 71.26 0.00e+00 4185.00
IUUC-Vda-129876 Verticillium dahliae 52.08 8.00e-09 55.10
IUUC-Vpa-130236 Vicugna pacos 69.22 0.00e+00 1558.00
IUUC-Vvi-131476 Vitis vinifera 33.88 2.00e-31 131.00
IUUC-Xtr-132455 Xenopus tropicalis 51.71 0.00e+00 925.00
Created Date 25-Jun-2017

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