iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013200

Ensembl Protein ID

ENSBTAP00000003589.5

UniProt Accession

A5PKD6; A5PKD6_BOVIN

Genbank Protein ID

AAI42450.1

Protein Name

GNB4 protein

Genbank Nucleotide ID

DAAA02001960

Gene Name

GNB4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000002767.5	ENSBTAT00000003589.5	ENSBTAP00000003589.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-39	130.5	224	258
UBD/Beta-Prp	2.50e-51	174.8	46	267

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH +++++++f ++   +++GsdD t++++Dlr +
   Q: 224  GHVSDINAVSFfPNgYAFATGSDDATCRLFDLRAD 258
           8*********99885679**************987 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
            + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   +h++   ++ v+++++ psg++++ G+ d++  +++l+t++    
   Q: 46   RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR 134
           446899*****************************************************************************987776 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
               l gh+g  +c ++ + ++ +v++s D+t+ lWd++t++  + +tg h ++v sls++++++ +vsg++d + klwd++ g c ++
   Q: 135  vsrELPGHTGYLSCCRFLD-DSQIVTSSGDTTCALWDIETAQQTTAFTG-HSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQS 221
           6779*************99.67789***********************9.*************************************** PP
   S: 218  lnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           ++gh + ++ v f+pn+  +++gs+D + r++dlr ++ l  +++ 
   Q: 222  FTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHD 267
           **************************************99888874 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MSELEQLRQE AEQLRNQIQD ARKACNDATL VQITSNMDSV GRIQMRTRRT LRGHLAKIYA 60
MHWGYDSRLL VSASQDGKLI IWDSYTTNKM HAIPLRSSWV MTCAYAPSGN YVACGGLDNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTGAGC TGGAACAACT GAGGCAGGAA GCCGAGCAGC TACGGAATCA GATCCAGGTA 60
AGAGCAAACT TTTTCATTTT GAAATTTTAT TAACACTTTT ATGAACTACT AGTGATGAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0007165--P:signal transduction
GO:0021762--P:substantia nigra development

KEGG

bta:525962

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001727	Ailuropoda melanoleuca	99.38	0.00e+00	664.00
IUUC-Apl-003923	Anas platyrhynchos	94.44	1.00e-175	608.00
IUUC-Aca-004754	Anolis carolinensis	94.43	3.00e-176	610.00
IUUC-Ate-010520	Aspergillus terreus	61.76	4.00e-110	390.00
IUUC-Cja-019845	Callithrix jacchus	99.38	0.00e+00	664.00
IUUC-Cfa-020395	Canis familiaris	99.38	0.00e+00	664.00
IUUC-Cpo-021376	Cavia porcellus	98.76	0.00e+00	662.00
IUUC-Csa-023295	Chlorocebus sabaeus	99.69	0.00e+00	665.00
IUUC-Cho-024766	Choloepus hoffmanni	99.08	0.00e+00	666.00
IUUC-Dno-029802	Dasypus novemcinctus	99.01	0.00e+00	625.00
IUUC-Dse-031388	Dothistroma septosporum	66.76	3.00e-137	481.00
IUUC-Dme-031748	Drosophila melanogaster	81.47	5.00e-173	599.00
IUUC-Ete-032710	Echinops telfairi	96.43	2.00e-179	620.00
IUUC-Eca-033628	Equus caballus	99.38	0.00e+00	664.00
IUUC-Eeu-034978	Erinaceus europaeus	97.07	4.00e-157	546.00
IUUC-Fal-037616	Ficedula albicollis	94.74	6.00e-177	612.00
IUUC-Gmo-039556	Gadus morhua	92.57	0.00e+00	625.00
IUUC-Gga-040249	Gallus gallus	94.74	6.00e-177	612.00
IUUC-Gac-041805	Gasterosteus aculeatus	91.64	0.00e+00	625.00
IUUC-Ggo-044954	Gorilla gorilla	99.38	0.00e+00	664.00
IUUC-Hsa-046105	Homo sapiens	99.69	0.00e+00	665.00
IUUC-Itr-048623	Ictidomys tridecemlineatus	99.69	0.00e+00	662.00
IUUC-Mcc-055787	Macaca mulatta	99.69	0.00e+00	665.00
IUUC-Mga-060050	Meleagris gallopavo	94.44	1.00e-175	608.00
IUUC-Mmr-060931	Microcebus murinus	99.69	0.00e+00	665.00
IUUC-Mdo-063055	Monodelphis domestica	94.12	3.00e-176	610.00
IUUC-Mmu-064368	Mus musculus	96.28	0.00e+00	649.00
IUUC-Mpu-066358	Mustela putorius furo	99.38	0.00e+00	664.00
IUUC-Mlu-067328	Myotis lucifugus	98.45	0.00e+00	658.00
IUUC-Nle-069612	Nomascus leucogenys	99.69	0.00e+00	665.00
IUUC-Ont-071287	Oreochromis niloticus	92.26	3.00e-180	624.00
IUUC-Oan-072913	Ornithorhynchus anatinus	95.05	6.00e-178	616.00
IUUC-Ocu-074126	Oryctolagus cuniculus	99.07	0.00e+00	668.00
IUUC-Ola-087297	Oryzias latipes	92.31	0.00e+00	628.00
IUUC-Oar-089360	Ovis aries	99.38	0.00e+00	663.00
IUUC-Ptr-091437	Pan troglodytes	99.69	0.00e+00	665.00
IUUC-Pan-092195	Papio anubis	99.38	0.00e+00	664.00
IUUC-Psi-093718	Pelodiscus sinensis	94.74	6.00e-177	612.00
IUUC-Pfo-096251	Poecilia formosa	92.26	3.00e-180	623.00
IUUC-Sce-106298	Saccharomyces cerevisiae	37.40	2.00e-68	253.00
IUUC-Sha-106534	Sarcophilus harrisii	94.12	1.00e-176	611.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	35.16	3.00e-59	221.00
IUUC-Spo-108352	Schizosaccharomyces pombe	41.69	1.00e-69	256.00
IUUC-Smo-108835	Selaginella moellendorffii	43.58	2.00e-74	272.00
IUUC-Sar-113642	Sorex araneus	98.90	8.00e-161	559.00
IUUC-Tgu-117198	Taeniopygia guttata	94.74	6.00e-177	612.00
IUUC-Tru-118399	Takifugu rubripes	91.64	5.00e-180	623.00
IUUC-Tsy-119354	Tarsius syrichta	96.28	0.00e+00	647.00
IUUC-Ttr-129243	Tursiops truncatus	99.69	0.00e+00	665.00
IUUC-Xtr-131924	Xenopus tropicalis	94.74	6.00e-177	613.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence