iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004324

UUCD1 version

UUC-AnC-00195

Ensembl Protein ID

ENSACAP00000003429.2

UniProt Accession

H9G7N0; H9G7N0_ANOCA

Protein Name

Uncharacterized protein

Gene Name

RNF19B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000003508.3	ENSACAT00000003514.3	ENSACAP00000003429.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.30e-49	169.4	148	348

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellv.eeelykryekllleevveadaalk 89
           C++Cl++++  +++ ll+C h+ C++Cl+qyl+++i e++ ++iscp  ec e+l++++i++ll  +++l+++ye++ll++++++d++++
   Q: 148  CPLCLVRQPSGNAPRLLSCPHRSCRACLRQYLRIEITESR-VHISCP--ECAERLDPADIRRLLRdSPQLVAKYEEFLLRRCLASDPDCR 234
           ****************************************.99****..89***********976257899******************* PP
   S: 90   wcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeek......eeaeskelleanskkCpkCkvyi 171
           wcpapdC ++v++  +a  +kl++e+e+c++efC++Ck++wH++++C+++++++a+t + +       ++ +++  ++++k+Cp+C++yi
   Q: 235  WCPAPDCGYAVIAYGCAscPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRtkhtsgLSYGQESGPADDIKPCPRCSAYI 324
           **************999899************************************99988888888888899999************** PP
   S: 172  ek..negCnhmtCakCkaefCwlC 193
           +k  +++CnhmtCa C++efCwlC
   Q: 325  IKmnDGSCNHMTCAVCGCEFCWLC 348
           *997889***************** PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MGSEKDSESP RSTSLPPQPA KCPGSGGGGN TNRRRRRLRL LSFQSVFSAA ASAASSSSGP 60
GVRRRKKAKA RPEPPIASKE EEAVAKEDEE EAKKAAEVGP PEEDAGAAAA PACEAPEEAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTTCGG AGAAGGACTC GGAGTCGCCG CGCTCGACCT CCCTCCCGCC TCAACCGGCC 60
AAATGCCCCG GAAGCGGCGG AGGCGGCAAC ACCAACCGCC GGCGTCGACG CCTCCGCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0044194--C:cytolytic granule
GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

acs:100560998

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002183	Ailuropoda melanoleuca	85.67	0.00e+00	944.00
IUUC-Apl-003468	Anas platyrhynchos	92.19	0.00e+00	867.00
IUUC-Ame-011813	Astyanax mexicanus	66.05	0.00e+00	696.00
IUUC-Bta-013135	Bos taurus	87.64	0.00e+00	987.00
IUUC-Cja-019264	Callithrix jacchus	78.97	0.00e+00	866.00
IUUC-Cpo-022502	Cavia porcellus	90.11	0.00e+00	882.00
IUUC-Cho-025032	Choloepus hoffmanni	70.96	0.00e+00	671.00
IUUC-Cin-025143	Ciona intestinalis	68.64	1.00e-45	176.00
IUUC-Dre-028769	Danio rerio	68.06	0.00e+00	744.00
IUUC-Dor-030551	Dipodomys ordii	94.97	5.00e-116	411.00
IUUC-Ete-033008	Echinops telfairi	75.43	0.00e+00	720.00
IUUC-Eca-033267	Equus caballus	88.78	0.00e+00	839.00
IUUC-Fca-035520	Felis catus	90.59	0.00e+00	838.00
IUUC-Fal-037090	Ficedula albicollis	91.56	0.00e+00	775.00
IUUC-Gga-041229	Gallus gallus	90.24	0.00e+00	757.00
IUUC-Gac-041619	Gasterosteus aculeatus	69.91	0.00e+00	736.00
IUUC-Hsa-045958	Homo sapiens	87.60	0.00e+00	996.00
IUUC-Itr-048425	Ictidomys tridecemlineatus	89.44	0.00e+00	885.00
IUUC-Lch-049552	Latimeria chalumnae	69.75	0.00e+00	914.00
IUUC-Loc-051738	Lepisosteus oculatus	67.61	0.00e+00	781.00
IUUC-Laf-054252	Loxodonta africana	85.71	0.00e+00	840.00
IUUC-Meu-055920	Macropus eugenii	91.36	0.00e+00	920.00
IUUC-Mga-059587	Meleagris gallopavo	89.68	0.00e+00	808.00
IUUC-Mdo-061985	Monodelphis domestica	88.42	0.00e+00	1024.00
IUUC-Mmu-064262	Mus musculus	87.64	0.00e+00	977.00
IUUC-Mpu-066101	Mustela putorius furo	87.54	0.00e+00	991.00
IUUC-Mlu-067347	Myotis lucifugus	88.74	0.00e+00	846.00
IUUC-Ont-071298	Oreochromis niloticus	68.86	0.00e+00	759.00
IUUC-Oan-073219	Ornithorhynchus anatinus	89.40	0.00e+00	855.00
IUUC-Ocu-073792	Oryctolagus cuniculus	88.58	0.00e+00	809.00
IUUC-Ola-086499	Oryzias latipes	69.97	0.00e+00	750.00
IUUC-Oga-088812	Otolemur garnettii	89.43	0.00e+00	948.00
IUUC-Oar-090353	Ovis aries	88.61	0.00e+00	886.00
IUUC-Psi-092988	Pelodiscus sinensis	92.94	0.00e+00	874.00
IUUC-Pfo-096268	Poecilia formosa	67.98	0.00e+00	763.00
IUUC-Pca-100597	Procavia capensis	90.16	0.00e+00	844.00
IUUC-Pva-102542	Pteropus vampyrus	77.09	0.00e+00	786.00
IUUC-Sha-106512	Sarcophilus harrisii	87.34	0.00e+00	988.00
IUUC-Sar-113233	Sorex araneus	87.83	0.00e+00	816.00
IUUC-Ssc-115781	Sus scrofa	87.58	0.00e+00	1013.00
IUUC-Tgu-117384	Taeniopygia guttata	97.95	0.00e+00	792.00
IUUC-Tru-117919	Takifugu rubripes	69.79	0.00e+00	746.00
IUUC-Tsy-119275	Tarsius syrichta	86.70	0.00e+00	826.00
IUUC-Tbe-127335	Tupaia belangeri	97.83	0.00e+00	664.00
IUUC-Ttr-128554	Tursiops truncatus	88.95	0.00e+00	835.00
IUUC-Vpa-130407	Vicugna pacos	82.31	0.00e+00	825.00
IUUC-Xtr-132325	Xenopus tropicalis	86.51	0.00e+00	734.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence