iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049459

Ensembl Protein ID

ENSLACP00000021681.1

UniProt Accession

H3BIG0; H3BIG0_LATCH

Genbank Protein ID

ENSLACP00000021681

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01002849

Gene Name

SOCS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000019050.1	ENSLACT00000021822.1	ENSLACP00000021681.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	57.08	5.00e-136	481.00	IUUC-Hsa-046322

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MSENKENTTR SVDVRPKTNR SRSADRRDGY AWSGKKRSWS NKNESFSDAE VLETVGKPGS 60
PLPRRERKHS SLTIDLAVEH SCGRKLSNRS LRQKLQDAMG QCFPIKAPGS RHAAVFTSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGAAA ATAAAGAAAA TACAACTAGA AGTGTGGACG TCAGACCAAA GACCAACAGA 60
AGCAGAAGCG CAGACAGACG GGATGGTTAC GCCTGGAGTG GAAAAAAACG TTCTTGGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028416--SOCS4
IPR022252--SOCS4/SOCS5_dom
IPR001496--SOCS_box

PROSITE

PS50225--SOCS

Pfam

PF12610--SOCS
PF07525--SOCS_box

SMART

SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001789	Ailuropoda melanoleuca	57.53	1.00e-129	456.00
IUUC-Apl-003839	Anas platyrhynchos	57.93	2.00e-124	438.00
IUUC-Aca-004840	Anolis carolinensis	56.68	3.00e-136	478.00
IUUC-Bta-012503	Bos taurus	57.99	2.00e-130	459.00
IUUC-Cja-019284	Callithrix jacchus	56.16	1.00e-129	456.00
IUUC-Cfa-020890	Canis familiaris	55.48	8.00e-128	450.00
IUUC-Cpo-022081	Cavia porcellus	54.69	4.00e-128	451.00
IUUC-Csa-023076	Chlorocebus sabaeus	56.62	5.00e-130	457.00
IUUC-Cho-024700	Choloepus hoffmanni	56.95	2.00e-137	482.00
IUUC-Dno-029961	Dasypus novemcinctus	56.95	2.00e-139	488.00
IUUC-Dor-030273	Dipodomys ordii	55.58	5.00e-129	454.00
IUUC-Eca-034289	Equus caballus	56.36	1.00e-130	459.00
IUUC-Eeu-035208	Erinaceus europaeus	55.30	8.00e-124	436.00
IUUC-Fal-036829	Ficedula albicollis	56.32	2.00e-120	425.00
IUUC-Gga-040725	Gallus gallus	57.70	4.00e-128	451.00
IUUC-Ggo-044886	Gorilla gorilla	56.39	9.00e-130	456.00
IUUC-Hsa-046322	Homo sapiens	56.16	2.00e-129	455.00
IUUC-Itr-048585	Ictidomys tridecemlineatus	56.25	2.00e-127	448.00
IUUC-Laf-053484	Loxodonta africana	56.68	5.00e-129	454.00
IUUC-Mcc-054890	Macaca mulatta	56.62	8.00e-130	456.00
IUUC-Meu-056532	Macropus eugenii	57.00	3.00e-114	404.00
IUUC-Mmr-061714	Microcebus murinus	57.08	4.00e-131	461.00
IUUC-Mmu-063161	Mus musculus	54.69	1.00e-120	426.00
IUUC-Mpu-066499	Mustela putorius furo	56.59	8.00e-137	479.00
IUUC-Mlu-066945	Myotis lucifugus	56.72	1.00e-126	446.00
IUUC-Nle-069976	Nomascus leucogenys	56.39	2.00e-129	455.00
IUUC-Opr-070255	Ochotona princeps	57.99	5.00e-129	454.00
IUUC-Ocu-074764	Oryctolagus cuniculus	56.01	1.00e-128	452.00
IUUC-Oga-088910	Otolemur garnettii	56.72	2.00e-131	461.00
IUUC-Oar-090330	Ovis aries	57.76	4.00e-130	457.00
IUUC-Ptr-090709	Pan troglodytes	56.39	9.00e-130	456.00
IUUC-Pan-092540	Papio anubis	56.62	5.00e-130	457.00
IUUC-Psi-093678	Pelodiscus sinensis	57.89	1.00e-143	503.00
IUUC-Pab-097970	Pongo abelii	53.72	6.00e-102	363.00
IUUC-Pca-100211	Procavia capensis	51.25	3.00e-111	395.00
IUUC-Rno-106014	Rattus norvegicus	54.00	4.00e-121	427.00
IUUC-Sha-106822	Sarcophilus harrisii	57.37	2.00e-130	458.00
IUUC-Ssc-115821	Sus scrofa	57.40	6.00e-132	463.00
IUUC-Tgu-117117	Taeniopygia guttata	56.78	2.00e-120	426.00
IUUC-Vpa-130626	Vicugna pacos	56.72	5.00e-130	457.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence